Catalog No.
PMC14601
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse ISG15 (Met1-Arg151).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Ubiquitin-like protein ISG15, Interferon-induced 15 kDa protein, Interferon-induced 17 kDa protein, IP17, Ubiquitin cross-reactive protein, Isg15, G1p2, Ucrp
Purification
Purified by antigen affinity column.
Accession
Q64339
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Type I IFN receptor blockade alleviates liver fibrosis through macrophage-derived STAT3 signaling., PMID:40260261
Identification of aberrant interferon-stimulated gene associated host responses potentially linked to poor prognosis in COVID-19 during the Omicron wave., PMID:40155905
Comparative analysis of immunogenicity for viral hemorrhagic septicemia virus (VHSV) vaccines inactivated by different methods., PMID:39986583
Proteomics and transcriptomics combined reveal specific immunological markers in autoimmune thyroid disease., PMID:39872521
B and T Cell Bi-Cistronic Multiepitopic Vaccine Induces Broad Immunogenicity and Provides Protection Against SARS-CoV-2., PMID:39591118
Overcoming Irinotecan Resistance by Targeting Its Downstream Signaling Pathways in Colon Cancer., PMID:39456585
Interferon-responsive neutrophils and macrophages extricate SARS-CoV-2 Omicron critical patients from the nasty fate of sepsis., PMID:39206862
Profiling of Early Immune Responses to Vaccination Using THP-1-Derived Dendritic Cells., PMID:38791547
Antagonism of regulatory ISGs enhances the anti-melanoma efficacy of STING agonists., PMID:38312842
Differential expression of Type I interferon and inflammatory genes in SARS-CoV-2-infected patients treated with monoclonal antibodies., PMID:37904704
First Identification and Pathogenicity Evaluation of an EV-G17 Strain Carrying a Torovirus Papain-like Cysteine Protease (PLCP) Gene in China., PMID:37632087
Antibody-dependent enhancement of porcine reproductive and respiratory syndrome virus infection downregulates the levels of interferon-gamma/lambdas in porcine alveolar macrophages in vitro., PMID:37008366
Type I interferon induced by polyinosinic-polycytidylic acid does not contribute to the efficacy of a formalin-killed cell vaccine against Edwardsiella piscicida in the Japanese flounder (Paralichthys olivaceus)., PMID:36914103
Engineered antibody cytokine chimera synergizes with DNA-launched nanoparticle vaccines to potentiate melanoma suppression in vivo., PMID:36911698
Endemic Burkitt lymphoma avatar mouse models for exploring inter-patient tumor variation and testing targeted therapies., PMID:36878637
IFNAR signaling of neuroectodermal cells is essential for the survival of C57BL/6 mice infected with Theiler's murine encephalomyelitis virus., PMID:36872323
Coxsackievirus A6 Infection Causes Neurogenic Pathogenesis in a Neonatal Murine Model., PMID:36851724
Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis., PMID:36812347
A Mass Spectrometry-Based Strategy for Mapping Modification Sites for the Ubiquitin-Like Modifier NEDD8., PMID:36446972
IFN-β mediates the anti-osteoclastic effect of bisphosphonates and dexamethasone., PMID:36386129
Single-cell profiling reveals distinct adaptive immune hallmarks in MDA5+ dermatomyositis with therapeutic implications., PMID:36309526
Species-specific transcriptomic changes upon respiratory syncytial virus infection in cotton rats., PMID:36195733
Functional analyses of two interferon-stimulated gene 15 (ISG15) copies in large yellow croaker, Larimichthys crocea., PMID:36007829
Assembly of ordered DNA-curli fibril complexes during Salmonella biofilm formation correlates with strengths of the type I interferon and autoimmune responses., PMID:35972973
Targeting MUC1-C Suppresses Chronic Activation of Cytosolic Nucleotide Receptors and STING in Triple-Negative Breast Cancer., PMID:35681561
mRNA-1273 vaccination protects against SARS-CoV-2-elicited lung inflammation in nonhuman primates., PMID:35653196
Association between interferon-I producing plasmacytoid dendritic cells and thrombotic antiphospholipid syndrome., PMID:35612283
In situ imaging for tumor microbiome interactions via imaging mass cytometry on single-cell level., PMID:35301803
Expression of Ki-67, Cornulin and ISG15 in non-involved mucosal surgical margins as predictive markers for relapse in oral squamous cell carcinoma (OSCC)., PMID:34941961
Maturation trajectories and transcriptional landscape of plasmablasts and autoreactive B cells in COVID-19., PMID:34723157
Neutrophil Extracellular Traps Contribute to COVID-19 Hyperinflammation and Humoral Autoimmunity., PMID:34685525
Proteome Modulation in Peripheral Blood Mononuclear Cells of Peste des Petits Ruminants Vaccinated Goats and Sheep., PMID:34631844
A QP509L/QP383R-Deleted African Swine Fever Virus Is Highly Attenuated in Swine but Does Not Confer Protection against Parental Virus Challenge., PMID:34613824
Novel DNA methylation markers of PRRSV-specific antibodies and their intergenerational transmission from pregnant sows to piglets., PMID:34274485
Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies., PMID:34270554
Comparative Analysis on Abnormal Methylome of Differentially Expressed Genes and Disease Pathways in the Immune Cells of RA and SLE., PMID:34079550
Investigation of type I interferon responses in ANCA-associated vasculitis., PMID:33859290
Shared inflammatory and skin-specific gene signatures reveal common drivers of discoid lupus erythematosus in canines, humans and mice., PMID:35492392
Proteomic Analysis of ISGylation in Immortalized Porcine Alveolar Macrophage Cell Lines Induced by Type I Interferon., PMID:33671165
Tumor Cell-Secreted ISG15 Promotes Tumor Cell Migration and Immune Suppression by Inducing the Macrophage M2-Like Phenotype., PMID:33424843
Restriction Factor Expression in Vertically Infected Children Living With HIV-1., PMID:33395209
From Diagnosis to Prognosis: Revisiting the Meaning of Muscle ISG15 Overexpression in Juvenile Inflammatory Myopathies., PMID:33314705
Asymptomatic Infection of Marburg Virus Reservoir Bats Is Explained by a Strategy of Immunoprotective Disease Tolerance., PMID:33157026
IFN-γ Mediates the Development of Systemic Lupus Erythematosus., PMID:33123584
Enhancement of HIV-1 Env-Specific CD8 T Cell Responses Using Interferon-Stimulated Gene 15 as an Immune Adjuvant., PMID:33115866
Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model., PMID:33072095
Transcriptome Profiling of Human Monocyte-Derived Macrophages Upon CCL2 Neutralization Reveals an Association Between Activation of Innate Immune Pathways and Restriction of HIV-1 Gene Expression., PMID:33072075
Host gene expression modulated by Zika virus infection of human-293 cells., PMID:33059318
PRRSV Vaccine Strain-Induced Secretion of Extracellular ISG15 Stimulates Porcine Alveolar Macrophage Antiviral Response against PRRSV., PMID:32927637
Interferon-stimulated genes inhibit caprine parainfluenza virus type 3 replication in Madin-Darby bovine kidney cells., PMID:31928705
For research use only. Not for human or drug use.
