Catalog No.
PMC10501
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse HSPB1/HSP27 (Ala76-Pro174).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Heat shock protein beta-1, HspB1, Growth-related 25 kDa protein, Heat shock 25 kDa protein, HSP 25, Heat shock 27 kDa protein, HSP 27, p25, Hspb1, Hsp25, Hsp27
Purification
Purified by antigen affinity column.
Accession
P14602
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Luminex-based pilot study identifies novel serum autoantibodies associated with disease activity in patients with lupus nephritis., PMID:40500568
Evidence that extracellular HSPB1 contributes to inflammation in alcohol-associated hepatitis., PMID:39281760
crVDAC3 alleviates ferroptosis by impeding HSPB1 ubiquitination and confers trastuzumab deruxtecan resistance in HER2-low breast cancer., PMID:39243601
Heat shock protein 27 in the pathogenesis of COVID-19 and non-COVID acute respiratory distress syndrome., PMID:37966617
FYN/TOPK/HSPB1 axis facilitates the proliferation and metastasis of gastric cancer., PMID:37016377
Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338
Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP., PMID:35235182
Physical activity level (PAL) and risk factors of cardiovascular disease in the MASHAD study cohort., PMID:34739910
Quaternary Structure and Hetero-Oligomerization of Recombinant Human Small Heat Shock Protein HspB7 (cvHsp)., PMID:34360542
Are IgG antibodies to heat shock proteins HSP27 and HSP60 useful markers in endometrial cancer and cervical cancer?, PMID:33914318
HSP25 Vaccination Attenuates Atherogenesis via Upregulation of LDLR Expression, Lowering of PCSK9 Levels and Curbing of Inflammation., PMID:33792343
Synergistic effect of collagen and CXCL12 in the low doses on human platelet activation., PMID:33119719
Evaluation of ABO blood group in subjects with CVD risk factors in a population sample from northeastern Iran., PMID:32905941
Serum levels of anti-heat shock protein 27 antibodies in patients with chronic liver disease., PMID:32895883
Prognostic Factors Associating with Pro-oxidant-antioxidant Balance; Neutrophils to Lymphocytes Ratio, Vitamin D, Heat Shock Protein 27, and Red Cell Distribution Width., PMID:32111498
Damage-Associated Molecular Patterns and Myeloid-Derived Suppressor Cells in Bronchoalveolar Lavage Fluid in Chronic Obstructive Pulmonary Disease Patients., PMID:31355298
Biophysical analyses and functional implications of the interaction between Heat Shock Protein 27 and antibodies to HSP27., PMID:31136785
Depression in adolescent girls: Relationship to serum vitamins a and E, immune response to heat shock protein 27 and systemic inflammation., PMID:30981058
Hsp-27 and NF-κB pathway is associated with AR/AR-V7 expression in prostate cancer cells., PMID:30807779
Is the small heat shock protein HspB1 (Hsp27) a real and predominant target of methylglyoxal modification?, PMID:30756294
Significance of serum antibodies against HPV E7, Hsp27, Hsp20 and Hp91 in Iranian HPV-exposed women., PMID:30755156
Anemia is associated with cognitive impairment in adolescent girls: A cross-sectional survey., PMID:30661397
Calcineurin/P38MAPK/HSP27-dependent pathways are involved in the attenuation of postischemic mitochondrial injury afforded by sodium bicarbonate co-transporter (NBCe1) inhibition., PMID:30615862
Downregulation of heat shock factor 4 transcription activity via MAPKinase phosphorylation at Serine 299., PMID:30316871
Comparative proteomic analysis reveals different responses in porcine lymph nodes to virulent and attenuated homologous African swine fever virus strains., PMID:30208957
The Effects of Curcumin on Serum Heat Shock Protein 27 Antibody Titers in Patients with Metabolic Syndrome., PMID:29958053
Chemokine CC-motif ligand 2 participates in platelet function and arterial thrombosis by regulating PKCα-P38MAPK-HSP27 pathway., PMID:29864522
Small heat shock protein speciation: novel non-canonical 44 kDa HspB5-related protein species in rat and human tissues., PMID:29542021
HSP27-Mediated Extracellular and Intracellular Signaling Pathways Synergistically Confer Chemoresistance in Squamous Cell Carcinoma of Tongue., PMID:29246940
Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function., PMID:28915917
Effect of Crocin on Antibody Titers to Heat-Shock Protein 27 in Subjects with Metabolic Syndrome., PMID:28486907
Relationship between serum anti-heat shock protein 27 antibody levels and obesity., PMID:28237841
Heat shock protein 27 is a potential indicator for response to YangZheng XiaoJi and chemotherapy agents in cancer cells., PMID:27600495
Course of serum autoantibodies in patients after acute angle-closure glaucoma attack., PMID:27758063
Expression of Heat Shock Protein 27 in Melanoma Metastases Is Associated with Overall Response to Bevacizumab Monotherapy: Analyses of Predictive Markers in a Clinical Phase II Study., PMID:27166673
Dp71Δ78-79 dystrophin mutant stimulates neurite outgrowth in PC12 cells via upregulation and phosphorylation of HspB1., PMID:26936078
Distinct and Synergistic Contributions of Epithelial Stress and Adaptive Immunity to Functions of Intraepithelial Killer Cells and Active Celiac Disease., PMID:26001928
Identification of heat shock protein 27 as a novel autoantigen of Behçet's disease., PMID:25529454
The effects of wet cupping on serum high-sensitivity C-reactive protein and heat shock protein 27 antibody titers in patients with metabolic syndrome., PMID:25146067
Barberry treatment reduces serum anti-heat shock protein 27 and 60 antibody titres and high-sensitivity c-reactive protein in patients with metabolic syndrome: a double-blind, randomized placebo-controlled trial., PMID:24536039
Lysine deacetylase inhibition promotes relaxation of arterial tone and C-terminal acetylation of HSPB6 (Hsp20) in vascular smooth muscle cells., PMID:24400135
Synergistic effect of lung tumor-associated dendritic cell-derived HB-EGF and CXCL5 on cancer progression., PMID:24346967
The role of estrogen receptor-α in estrogen-mediated regulation of basal and exercise-induced Hsp70 and Hsp27 expression in rat soleus., PMID:24303535
Expression of Hsp27 correlated with rat detrusor contraction after acute urinary retention., PMID:23740515
Effect of zinc supplementation on serum antibody titers to heat shock protein 27 in patients with thalassemia major., PMID:23683800
O-GlcNAcylation of αB-crystallin regulates its stress-induced translocation and cytoprotection., PMID:23543138
Netrin-1 protects hypoxia-induced mitochondrial apoptosis through HSP27 expression via DCC- and integrin α6β4-dependent Akt, GSK-3β, and HSF-1 in mesenchymal stem cells., PMID:23538444
Curcuminoids modulate pro-oxidant-antioxidant balance but not the immune response to heat shock protein 27 and oxidized LDL in obese individuals., PMID:23494802
Antioxidants reduce TGF-beta2-induced gene expressions in human optic nerve head astrocytes., PMID:23280001
Enhanced cell survival and diminished apoptotic response to simulated ischemia-reperfusion in H9c2 cells by magnetic field preconditioning., PMID:22960730
For research use only. Not for human or drug use.
