Catalog No.
PHN49701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MXRA8 (His23-Glu293).
Applications
ELISA, IHC, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:4000-1:8000, IHC: 1:50-1:300, WB: 1:500-1:2000 |
Target
Matrix remodeling-associated protein 8, Limitrin, MXRA8
Concentration
1 mg/ml
Purification
Purified by antigen affinity column.
Accession
Q9BRK3
Form
Liquid
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
Limitrin, a novel immunoglobulin superfamily protein localized to glia limitans formed by astrocyte endfeet., PMID:14603461
Limitin, an interferon-like cytokine, transduces inhibitory signals on B-cell growth through activation of Tyk2, but not Stat1, followed by induction and nuclear translocation of Daxx., PMID:14662340
Mxra8 is a receptor for multiple arthritogenic alphaviruses., PMID:29769725
Dermal and muscle fibroblasts and skeletal myofibers survive chikungunya virus infection and harbor persistent RNA., PMID:31465513
Expression of the Mxra8 Receptor Promotes Alphavirus Infection and Pathogenesis in Mice and Drosophila., PMID:31484075
An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis., PMID:32075743
Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease., PMID:32365139
Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site., PMID:32783883
Structural basis of Chikungunya virus inhibition by monoclonal antibodies., PMID:33087569
Cryo-EM structure of the mature and infective Mayaro virus at 4.4 Å resolution reveals features of arthritogenic alphaviruses., PMID:34031424
Protective Role of Limitrin in Experimental Autoimmune Optic Neuritis., PMID:34232258
Chikungunya and arthritis: An overview., PMID:34563686
Structure of Venezuelan equine encephalitis virus in complex with the LDLRAD3 receptor., PMID:34646020
Matrix remodeling-associated protein 8 is a marker of a subset of cancer-associated fibroblasts in pancreatic cancer., PMID:35020975
Identification of the receptor of oncolytic virus M1 as a therapeutic predictor for multiple solid tumors., PMID:35393389
Elevated Expression of miR-200c/141 in MDA-MB-231 Cells Suppresses MXRA8 Levels and Impairs Breast Cancer Growth and Metastasis In Vivo., PMID:35456497
The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito., PMID:37018377
Role of MXRA8 in Ross River Virus Disease Pathogenesis., PMID:37036079
Chikungunya virus cell-to-cell transmission is mediated by intercellular extensions in vitro and in vivo., PMID:37591996
Loss of MXRA8 Delays Mammary Tumor Development and Impairs Metastasis., PMID:37762032
Single-cell RNA combined with bulk RNA analysis to explore oxidative stress and energy metabolism factors and found a new prostate cancer oncogene MXRA8., PMID:38441550
For research use only. Not for human or drug use.
