Catalog No.
PHJ17401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PDPN/Podoplanin (Ala23-Leu131).
Applications
ELISA, IHC, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000 |
Target
Podoplanin, Aggrus, Glycoprotein 36, Gp36, PA2.26 antigen, T1-alpha, T1A, 29kDa cytosolic podoplanin intracellular domain, PICD, PDPN, GP36, PSEC0003, PSEC0025
Purification
Purified by antigen affinity column.
Accession
Q86YL7
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
Encapsulating Peritoneal Sclerosis in Systemic Lupus Erythematosus, Rheumatoid Arthritis, and Systemic Sclerosis., PMID:36288993
Utility of a Highly Specific and Sensitive Podoplanin/D2-40, Calretinin, Thyroid Transcription Factor-1, and Carcinoembryonic Antigen/CD66e Immunohistochemical Panel in Differentiating Malignant Pleural Mesothelioma from Metastatic Adenocarcinoma: An Egyptian Experience., PMID:39507645
[Research progress on the mechanism of role of podoplanin in sepsis]., PMID:36377457
Development of a new histological identification method of human sinoatrial node suitable for immunohistochemical study., PMID:36422826
Expression of Claudin-4 and D2-40 and their significance in prostatic adenocarcinoma., PMID:38384059
Chondrosarcoma with Target-Like Chondrocytes: Update on Molecular Profiling and Specific Morphological Features., PMID:36689318
PDPN positive CAFs contribute to HER2 positive breast cancer resistance to trastuzumab by inhibiting antibody-dependent NK cell-mediated cytotoxicity., PMID:36812747
Lymph Node Transfer and Neolymphangiogenesis: From Theory to Evidence., PMID:36940155
Cancer-associated fibroblasts promote venous thrombosis through podoplanin/CLEC-2 interaction in podoplanin-negative lung cancer mouse model., PMID:37473844
Podoplanin Drives Amoeboid Invasion in Canine and Human Mucosal Melanoma., PMID:37493578
Podoplanin promotes cell proliferation, survival, and migration of canine non-tonsillar squamous cell carcinoma., PMID:37544715
The role of blood podoplanin in patients with viral myocarditis., PMID:37669599
Prognostic Nomogram for Lymph-Node Metastasis in Oral Squamous Cell Carcinoma (OSCC) Using Immunohistochemical Marker D2-40., PMID:37674659
CSF-1 and Notch signaling cooperate in macrophage instruction and tissue repair during peripheral limb ischemia., PMID:37691936
A Humanized and Defucosylated Antibody against Podoplanin (humLpMab-23-f) Exerts Antitumor Activities in Human Lung Cancer and Glioblastoma Xenograft Models., PMID:37894446
The Usefulness of Elastin Staining to Detect Vascular Invasion in Cancer., PMID:37894944
The role of podoplanin inhibitors in controlling oral cancer progression., PMID:37952507
Potential significance of podoplanin immunohistochemical expression in papillary thyroid carcinoma., PMID:37955536
Antipodoplanin antibody enhances the antitumor effects of CTLA-4 blockade against malignant mesothelioma by natural killer cells., PMID:38148492
PMab-301: An Anti-Giraffe Podoplanin Monoclonal Antibody for Immunohistochemistry., PMID:38150189
Epitope Mapping of an Anti-ferret Podoplanin Monoclonal Antibody Using the PA Tag-Substituted Analysis., PMID:38156889
Near-infrared-II Ag2S quantum dot probes targeting podoplanin enhance immunotherapy in oral squamous cell carcinoma., PMID:38157644
A novel PDPN antagonist peptide CY12-RP2 inhibits melanoma growth via Wnt/β-catenin and modulates the immune cells., PMID:38167452
Abnormalities in C-type lectin-like receptor 2 in a patient with Gorham-Stout disease: the first case report., PMID:38187828
Tumor Suppression by Anti-Fibroblast Activation Protein Near-Infrared Photoimmunotherapy Targeting Cancer-Associated Fibroblasts., PMID:38275890
[Novel Therapy Targeting the Cancer Microenvironment Using Near-Infrared Photoimmunotherapy Leading to Tumor Immune Activation]., PMID:38303275
Isolation and In Vitro Culture of Germ Cells and Sertoli Cells from Human Fetal Testis., PMID:38351447
Interaction between NSCLC Cells, CD8+ T-Cells and Immune Checkpoint Inhibitors Potentiates Coagulation and Promotes Metabolic Remodeling-New Cues on CAT-VTE., PMID:38391918
Evaluation of immuno-histochemical markers in oral squamous cell carcinoma., PMID:38415034
C-type lectin-like receptor 2: roles and drug target., PMID:38504248
A novel therapy for fracture healing by increasing lymphatic drainage., PMID:38511124
PMab-314: An Anti-Giant Panda Podoplanin Monoclonal Antibody., PMID:38593441
Tumor-matched and unmatched cancer associated fibroblasts exhibit differential effect on proliferation and FMOD and MMP9 gene expression in head and neck squamous cell carcinoma cells when cocultured in spheroids., PMID:38822309
CAFs-Associated Genes (CAFGs) in Pancreatic Ductal Adenocarcinoma (PDAC) and Novel Therapeutic Strategy., PMID:38892190
Morphofunctional Characteristics of the Vessels of the Subareolar Lymphatic Plexus in Breast Cancer with Metastasis to the Lymph Nodes of the Axillary Lymphatic Collector., PMID:39138790
Cancer-Associated Fibroblast Proteins as Potential Targets against Colorectal Cancers., PMID:39335130
The prognostic implications of podoplanin in cancer-associated fibroblasts and PD-L1 expression in high-grade neuroendocrine carcinoma of the lung., PMID:39487962
Benzo (A) pyrene exposure alters alveolar epithelial and macrophage cells diversity and induces antioxidant responses in lungs., PMID:39506978
Decoding lymphangiogenesis in oral squamous cell carcinoma: Emphasis on clinical and histopathological determinants of regional metastasis., PMID:39541328
Exploring the Interplay Between Senescent Osteocytes and Bone Remodeling in Young Rodents., PMID:39583064
A Cancer-Specific Anti-Podoplanin Monoclonal Antibody, PMab-117-mG2a Exerts Antitumor Activities in Human Tumor Xenograft Models., PMID:39594582
ROLE OF IMMUNOHISTOCHEMICAL EXPRESSION OF D2-40 MARKER IN HIGH-GRADE DYSPLASIA, MICROINVASIVE AND FRANKLY INVASIVE ORAL SQUAMOUS CELL CARCINOMA., PMID:39623817
PDPN+ cancer-associated fibroblasts enhance gastric cancer angiogenesis via AKT/NF-κB activation and the CCL2-ACKR1 axis., PMID:39764562
Lymphangioinvasion detection using the monoclonal antibody D2-40 (Podoplanin)as a clinical predictor of axillary lymph node metastasis in breast cancer patients., PMID:39988774
A proteogenomic tool uncovers protein markers for human microglial states., PMID:40236015
Lymphangiogenesis in the Deepest Invasive Areas of Human Early-Stage Colorectal Cancer., PMID:40243510
VEGF-C and Lymphatic Vessel Density in Tumor Tissue of Gastric Cancer: Correlations with Pathoclinical Features and Prognosis., PMID:40361332
Treatment of Pancreatic Cancer Using Near-Infrared Photoimmunotherapy Targeting Cancer-Associated Fibroblasts in Combination with Anticancer Chemotherapeutic Drug., PMID:40361512
Antitumor Activities by a Humanized Cancer-Specific Anti-Podoplanin Monoclonal Antibody humPMab-117 Against Human Tumors., PMID:40393461
HIV-associated preeclampsia: evaluation of lymphangiogenesis in placental bed samples., PMID:40402284
For research use only. Not for human or drug use.
