Anti-Human PDPN/Podoplanin Polyclonal Antibody

Catalog No.

PHJ17401

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PDPN/Podoplanin (Ala23-Leu131).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Podoplanin, Aggrus, Glycoprotein 36, Gp36, PA2.26 antigen, T1-alpha, T1A, 29kDa cytosolic podoplanin intracellular domain, PICD, PDPN, GP36, PSEC0003, PSEC0025

Purification

Purified by antigen affinity column.

Accession

Q86YL7

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

HIV-associated preeclampsia: evaluation of lymphangiogenesis in placental bed samples., PMID:40402284

Antitumor Activities by a Humanized Cancer-Specific Anti-Podoplanin Monoclonal Antibody humPMab-117 Against Human Tumors., PMID:40393461

Treatment of Pancreatic Cancer Using Near-Infrared Photoimmunotherapy Targeting Cancer-Associated Fibroblasts in Combination with Anticancer Chemotherapeutic Drug., PMID:40361512

VEGF-C and Lymphatic Vessel Density in Tumor Tissue of Gastric Cancer: Correlations with Pathoclinical Features and Prognosis., PMID:40361332

Lymphangiogenesis in the Deepest Invasive Areas of Human Early-Stage Colorectal Cancer., PMID:40243510

A proteogenomic tool uncovers protein markers for human microglial states., PMID:40236015

Lymphangioinvasion detection using the monoclonal antibody D2-40 (Podoplanin)as a clinical predictor of axillary lymph node metastasis in breast cancer patients., PMID:39988774

PDPN+ cancer-associated fibroblasts enhance gastric cancer angiogenesis via AKT/NF-κB activation and the CCL2-ACKR1 axis., PMID:39764562

ROLE OF IMMUNOHISTOCHEMICAL EXPRESSION OF D2-40 MARKER IN HIGH-GRADE DYSPLASIA, MICROINVASIVE AND FRANKLY INVASIVE ORAL SQUAMOUS CELL CARCINOMA., PMID:39623817

A Cancer-Specific Anti-Podoplanin Monoclonal Antibody, PMab-117-mG2a Exerts Antitumor Activities in Human Tumor Xenograft Models., PMID:39594582

Exploring the Interplay Between Senescent Osteocytes and Bone Remodeling in Young Rodents., PMID:39583064

Decoding lymphangiogenesis in oral squamous cell carcinoma: Emphasis on clinical and histopathological determinants of regional metastasis., PMID:39541328

Benzo (A) pyrene exposure alters alveolar epithelial and macrophage cells diversity and induces antioxidant responses in lungs., PMID:39506978

The prognostic implications of podoplanin in cancer-associated fibroblasts and PD-L1 expression in high-grade neuroendocrine carcinoma of the lung., PMID:39487962

Cancer-Associated Fibroblast Proteins as Potential Targets against Colorectal Cancers., PMID:39335130

Morphofunctional Characteristics of the Vessels of the Subareolar Lymphatic Plexus in Breast Cancer with Metastasis to the Lymph Nodes of the Axillary Lymphatic Collector., PMID:39138790

CAFs-Associated Genes (CAFGs) in Pancreatic Ductal Adenocarcinoma (PDAC) and Novel Therapeutic Strategy., PMID:38892190

Tumor-matched and unmatched cancer associated fibroblasts exhibit differential effect on proliferation and FMOD and MMP9 gene expression in head and neck squamous cell carcinoma cells when cocultured in spheroids., PMID:38822309

PMab-314: An Anti-Giant Panda Podoplanin Monoclonal Antibody., PMID:38593441

A novel therapy for fracture healing by increasing lymphatic drainage., PMID:38511124

C-type lectin-like receptor 2: roles and drug target., PMID:38504248

Evaluation of immuno-histochemical markers in oral squamous cell carcinoma., PMID:38415034

Interaction between NSCLC Cells, CD8+ T-Cells and Immune Checkpoint Inhibitors Potentiates Coagulation and Promotes Metabolic Remodeling-New Cues on CAT-VTE., PMID:38391918

Isolation and In Vitro Culture of Germ Cells and Sertoli Cells from Human Fetal Testis., PMID:38351447

[Novel Therapy Targeting the Cancer Microenvironment Using Near-Infrared Photoimmunotherapy Leading to Tumor Immune Activation]., PMID:38303275

Tumor Suppression by Anti-Fibroblast Activation Protein Near-Infrared Photoimmunotherapy Targeting Cancer-Associated Fibroblasts., PMID:38275890

Abnormalities in C-type lectin-like receptor 2 in a patient with Gorham-Stout disease: the first case report., PMID:38187828

A novel PDPN antagonist peptide CY12-RP2 inhibits melanoma growth via Wnt/β-catenin and modulates the immune cells., PMID:38167452

Near-infrared-II Ag2S quantum dot probes targeting podoplanin enhance immunotherapy in oral squamous cell carcinoma., PMID:38157644

Epitope Mapping of an Anti-ferret Podoplanin Monoclonal Antibody Using the PA Tag-Substituted Analysis., PMID:38156889

PMab-301: An Anti-Giraffe Podoplanin Monoclonal Antibody for Immunohistochemistry., PMID:38150189

Antipodoplanin antibody enhances the antitumor effects of CTLA-4 blockade against malignant mesothelioma by natural killer cells., PMID:38148492

Potential significance of podoplanin immunohistochemical expression in papillary thyroid carcinoma., PMID:37955536

The role of podoplanin inhibitors in controlling oral cancer progression., PMID:37952507

The Usefulness of Elastin Staining to Detect Vascular Invasion in Cancer., PMID:37894944

A Humanized and Defucosylated Antibody against Podoplanin (humLpMab-23-f) Exerts Antitumor Activities in Human Lung Cancer and Glioblastoma Xenograft Models., PMID:37894446

CSF-1 and Notch signaling cooperate in macrophage instruction and tissue repair during peripheral limb ischemia., PMID:37691936

Prognostic Nomogram for Lymph-Node Metastasis in Oral Squamous Cell Carcinoma (OSCC) Using Immunohistochemical Marker D2-40., PMID:37674659

The role of blood podoplanin in patients with viral myocarditis., PMID:37669599

Podoplanin promotes cell proliferation, survival, and migration of canine non-tonsillar squamous cell carcinoma., PMID:37544715

Podoplanin Drives Amoeboid Invasion in Canine and Human Mucosal Melanoma., PMID:37493578

Cancer-associated fibroblasts promote venous thrombosis through podoplanin/CLEC-2 interaction in podoplanin-negative lung cancer mouse model., PMID:37473844

Lymph Node Transfer and Neolymphangiogenesis: From Theory to Evidence., PMID:36940155

PDPN positive CAFs contribute to HER2 positive breast cancer resistance to trastuzumab by inhibiting antibody-dependent NK cell-mediated cytotoxicity., PMID:36812747

Chondrosarcoma with Target-Like Chondrocytes: Update on Molecular Profiling and Specific Morphological Features., PMID:36689318

Expression of Claudin-4 and D2-40 and their significance in prostatic adenocarcinoma., PMID:38384059

Development of a new histological identification method of human sinoatrial node suitable for immunohistochemical study., PMID:36422826

[Research progress on the mechanism of role of podoplanin in sepsis]., PMID:36377457

Utility of a Highly Specific and Sensitive Podoplanin/D2-40, Calretinin, Thyroid Transcription Factor-1, and Carcinoembryonic Antigen/CD66e Immunohistochemical Panel in Differentiating Malignant Pleural Mesothelioma from Metastatic Adenocarcinoma: An Egyptian Experience., PMID:39507645

Encapsulating Peritoneal Sclerosis in Systemic Lupus Erythematosus, Rheumatoid Arthritis, and Systemic Sclerosis., PMID:36288993

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