Catalog No.
PHJ87201
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RNF11 (Met1-Asn154).
Applications
ELISA, IHC, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:4000-1:8000, IHC: 1:50-1:200, WB: 1:500-1:2000 |
Target
RING finger protein 11,RNF11
Concentration
1 mg/ml
Purification
Purified by antigen affinity column.
Accession
Q9Y3C5
Form
Liquid
Storage buffer
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase., PMID:14562029
Molecular characterization of ring finger protein 11., PMID:16123141
PARK10 candidate RNF11 is expressed by vulnerable neurons and localizes to Lewy bodies in Parkinson disease brain., PMID:17917589
The RING finger protein11 binds to Smad4 and enhances Smad4-dependant TGF-beta signalling., PMID:19528490
The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1., PMID:21765415
NF-κB activity is inversely correlated to RNF11 expression in Parkinson's disease., PMID:23669642
SARA and RNF11 at the crossroads of EGFR signaling and trafficking., PMID:24377927