Catalog No.
PHG58701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human NEUROD1 (Thr2-Asp356).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Neurogenic differentiation factor 1, NeuroD, NeuroD1, Class A basic helix-loop-helix protein 3, bHLHa3, NEUROD1, BHLHA3, NEUROD
Purification
Purified by antigen affinity column.
Accession
Q13562
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Transient islet-antigen 2 positivity at diagnosis of diabetes during COVID-19 infection in an adolescent with a NEUROD1 variant: a case report., PMID:40474235
Molecular subtyping dictates therapeutic response to anti-PD-L1 immunotherapy in ES-SCLC., PMID:40402312
The Potential of Single-Transcription Factor Gene Expression by RT-qPCR for Subtyping Small Cell Lung Cancer., PMID:39941061
Dual onsets of small cell lung cancer with contrasting neuroendocrine features and immune microenvironments: A case report., PMID:39919549
Beta cell-specific PAK1 enrichment ameliorates diet-induced glucose intolerance in mice by promoting insulin biogenesis and minimising beta cell apoptosis., PMID:39404845
A novel nonsense mutation c.747C>G in the NEUROD1 gene detected within a Chinese family affected by maturity-onset diabetes of the young type 6., PMID:39264012
A Newly Developed Anti-L1CAM Monoclonal Antibody Targets Small Cell Lung Carcinoma Cells., PMID:39201435
Clinical and Laboratory Characteristics of MODY Cases, Genetic Mutation Spectrum and Phenotype-genotype Relationship., PMID:38665000
Reprogramming of astrocytes to neuronal-like cells in spinal cord injury: a systematic review., PMID:38448665
Screening of Mutations in Maturity-onset Diabetes of the Young-related Genes and RFX6 in Children with Autoantibody-negative Type 1 Diabetes Mellitus., PMID:38054414
Pathologic diagnosis of lung cancer - recent developments., PMID:37975321
Identification of Lineage-specific Transcriptional Factor-defined Molecular Subtypes in Small Cell Bladder Cancer., PMID:37380560
CRISPR/Cas9-Mediated Knockout of tnfaip1 in Zebrafish Plays a Role in Early Development., PMID:37239365
Whole-Section Landscape Analysis of Molecular Subtypes in Curatively Resected Small Cell Lung Cancer: Clinicopathologic Features and Prognostic Significance., PMID:37054974
Identification of inflamed-phenotype of small cell lung cancer leading to the efficacy of anti-PD-L1 antibody and chemotherapy., PMID:37037178
NeuroD1 localizes to the presumptive ganglia and gut of the sea urchin larvae., PMID:36468156
Stress Induced Hyperglycemia in Early Childhood as a Clue for the Diagnosis of NEUROD1-MODY., PMID:36047484
Immune Checkpoint Blockade Outcome in Small-Cell Lung Cancer and Its Relationship With Retinoblastoma Mutation Status and Function., PMID:36044718
Pancreatic-Like Cells Derived From Mouse Embryonic Stem Cells Are Regulated by Pdx1 Involving the Notch Pathway., PMID:35695761
Identification of Variants Responsible for Monogenic Forms of Diabetes in Brazil., PMID:35592779
Differentiation of PC12 cell line into neuron by Valproic acid encapsulated in the stabilized core-shell liposome-chitosan Nano carriers., PMID:35537586
Molecular subtypes of small cell lung cancer transformed from adenocarcinoma after EGFR tyrosine kinase inhibitor treatment., PMID:35004251
Differential Morphological Diagnosis of Various Forms of Congenital Hyperinsulinism in Children., PMID:34497584
Targeting netrin-3 in small cell lung cancer and neuroblastoma., PMID:33719214
SCLC-CellMiner: A Resource for Small Cell Lung Cancer Cell Line Genomics and Pharmacology Based on Genomic Signatures., PMID:33086069
Clinical and laboratory clues of maturity-onset diabetes of the young and determination of association with molecular diagnosis., PMID:32710514
Morphological and immunophenotypic characterization of perivascular interstitial cells in human glioma: Telocytes, pericytes, and mixed immunophenotypes., PMID:32064038
In vivo ectopic Ngn1 and Neurod1 convert neonatal cochlear glial cells into spiral ganglion neurons., PMID:32027432
Intestinal Neurod1 expression impairs paneth cell differentiation and promotes enteroendocrine lineage specification., PMID:31862906
Herpes Simplex Virus Type-1 Infection Impairs Adult Hippocampal Neurogenesis via Amyloid-β Protein Accumulation., PMID:31381841
Analysis of pituitary adenoma expression patterns suggests a potential role for the NeuroD1 transcription factor in neuroendocrine tumor-targeting therapies., PMID:30719226
Multihormonal pituitary adenoma concomitant with Pit-1 and Tpit lineage cells causing acromegaly associated with subclinical Cushing's disease: a case report., PMID:28865461
Targeted next-generation sequencing reveals MODY in up to 6.5% of antibody-negative diabetes cases listed in the Norwegian Childhood Diabetes Registry., PMID:27913849
In vitro reprogramming of rat bmMSCs into pancreatic endocrine-like cells., PMID:27699654
Nur77 gene expression levels were involved in different ACTH-secretion autonomy between Cushing's disease and subclinical Cushing's disease., PMID:27025408
Micropatterning Extracellular Matrix Proteins on Electrospun Fibrous Substrate Promote Human Mesenchymal Stem Cell Differentiation Toward Neurogenic Lineage., PMID:26654444
Hypoxic preconditioning differentially affects GABAergic and glutamatergic neuronal cells in the injured cerebellum of the neonatal rat., PMID:25032984
Differentiation of iPSCs into insulin-producing cells via adenoviral transfection of PDX-1, NeuroD1 and MafA., PMID:24794627
A novel activator of CBP/p300 acetyltransferases promotes neurogenesis and extends memory duration in adult mice., PMID:23804093
The transcription factor Myt3 acts as a pro-survival factor in β-cells., PMID:23236509
Expression and localization of CERKL in the mammalian retina, its response to light-stress, and relationship with NeuroD1 gene., PMID:23142158
MiR-34a represses Numbl in murine neural progenitor cells and antagonizes neuronal differentiation., PMID:22701667
Long-term survival and differentiation of retinal neurons derived from human embryonic stem cell lines in un-immunosuppressed mouse retina., PMID:22539871
Regeneration and DNA demethylation do not trigger PDX-1 expression in rat hepatocytes., PMID:21537485
Xenograft of microencapsulated sertoli cells reverses T1DM in NOD mice by inducing neogenesis of beta-cells., PMID:21197711
Exposure to extremely low-frequency (50 Hz) electromagnetic fields enhances adult hippocampal neurogenesis in C57BL/6 mice., PMID:20816824
Neurod1 suppresses hair cell differentiation in ear ganglia and regulates hair cell subtype development in the cochlea., PMID:20661473
Retinoic acid directs neuronal differentiation of human pluripotent stem cell lines in a non-cell-autonomous manner., PMID:20427117
Insulin but not glucagon gene is silenced in human pancreas-derived mesenchymal stem cells., PMID:19785038
A-beta-subtype of ketosis-prone diabetes is not predominantly a monogenic diabetic syndrome., PMID:19228875
For research use only. Not for human or drug use.
