Catalog No.
PHF33901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DEFB1 (Gly22-Lys68).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Beta-defensin 1, BD-1, hBD-1, Defensin, beta 1, DEFB1, BD1, HBD1
Purification
Purified by antigen affinity column.
Accession
P60022
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Association between DEFB1 rs11362 and Caries Susceptibility in Permanent Dentition: A Cross Sectional Study., PMID:39327247
Antibacterial and immunomodulatory effects of Pheromonicin-NM on Escherichia coli-challenged bovine mammary epithelial cells., PMID:32413738
β-Defensin 1 Is Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids via Farnesoid X Receptor and Constitutive Androstane Receptor., PMID:30100908
Targeting PI3K/mTOR Signaling Displays Potent Antitumor Efficacy against Nonfunctioning Pituitary Adenomas., PMID:25838390
[Influence of OM-85 BV on hBD-1 and immunoglobulin in children with asthma and recurrent respiratory tract infection]., PMID:24857002
Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer's brain., PMID:24139179
[Serum levels of human β-defensins 1 and immunoglobulins A, G and M in infants with recurrent pneumonia]., PMID:22738449
Localization of inflammatory mediators in pediatric sinus mucosa., PMID:22508623
Functional single-nucleotide polymorphisms in the DEFB1 gene are associated with systemic lupus erythematosus in Southern Brazilians., PMID:22323338
Effects of endotoxin exposure on childhood asthma risk are modified by a genetic polymorphism in ACAA1., PMID:22151743
Genetic determinants of immune-response to a polysaccharide vaccine for typhoid., PMID:21119757
Hint for association of single nucleotide polymorphisms and haplotype in SPINK5 gene with atopic dermatitis in Koreans., PMID:21087323
Mechanical and metabolic injury to the skin barrier leads to increased expression of murine β-defensin-1, -3, and -14., PMID:20944649
Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon., PMID:20421464
The potent adjuvant effects of chicken beta-defensin-1 when genetically fused with infectious bursal disease virus VP2 gene., PMID:20334934
Low expression of human beta-defensin 1 in duodenum of celiac patients is partially restored by a gluten-free diet., PMID:20128731
Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment., PMID:19956723
Association between DEFB1 gene haplotype and herpes viruses seroprevalence in children with acute lymphoblastic leukemia., PMID:19954367
Association of beta-defensin 1 single nucleotide polymorphism with atopic dermatitis., PMID:22059360
Expression of human beta-defensin -1, -2, and -3 in non-inflamed pseudocyst, mucoceles., PMID:18627502
Interaction between seroreactivity to microbial antigens and genetics in Crohn's disease: is there a role for defensins?, PMID:18397186
Innate immunity in the human female reproductive tract: antiviral response of uterine epithelial cells to the TLR3 agonist poly(I:C)., PMID:15634923
Proteus mirabilis ZapA metalloprotease degrades a broad spectrum of substrates, including antimicrobial peptides., PMID:15322010
Detection of HBD1 peptide in peripheral blood mononuclear cell subpopulations by intracellular flow cytometry., PMID:15019211
Human beta-defensin-2 functions as a chemotactic agent for tumour necrosis factor-alpha-treated human neutrophils., PMID:15009427
Decreased excretion of antimicrobial proteins and peptides in saliva of patients with oral candidiasis., PMID:14632933
Cancer-specific loss of beta-defensin 1 in renal and prostatic carcinomas., PMID:12695553
Defensin-induced adaptive immunity in mice and its potential in preventing periodontal disease., PMID:12654098
Expression of the peptide antibiotics human beta defensin-1 and human beta defensin-2 in normal human skin., PMID:11442756
Expression of human beta-defensins in intraocular tissues., PMID:10967060
Structural analysis of human beta-defensin-1 and its significance in urinary tract infection., PMID:10773753
Inducible expression of human beta-defensin 2 by Fusobacterium nucleatum in oral epithelial cells: multiple signaling pathways and role of commensal bacteria in innate immunity and the epithelial barrier., PMID:10768988
Structure and mapping of the human beta-defensin HBD-2 gene and its expression at sites of inflammation., PMID:9831658
Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung., PMID:9727055
For research use only. Not for human or drug use.
