Catalog No.
PHE81901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human INSL3 (Leu21-Tyr131).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Insulin-like 3, Leydig insulin-like peptide, Ley-I-L, Relaxin-like factor, Insulin-like 3 B chain, Insulin-like 3 A chain, INSL3, RLF, RLNL
Purification
Purified by antigen affinity column.
Accession
P51460
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Discovery of RXFP2 genetic association in resistant hypertensive men and RXFP2 antagonists for the treatment of resistant hypertension., PMID:38851835
Expression of Insl3 Protein in Adult Danio rerio., PMID:38791457
Endocrine and dog factors associated with semen quality., PMID:38184699
Shortwave radiation-induced reproductive organ damage in male rats by enhanced expression of molecules associated with the calpain/Cdk5 pathway and oxidative stress., PMID:38155529
Isolation of Leydig cells from adult rat testes by magnetic-activated cell sorting protocol based on prolactin receptor expression., PMID:35735181
Association of antimullerian hormone with the size of the appendix testis, the androgen and estrogen receptors and their expression in the appendix testis, in congenital cryptorchidism., PMID:34265880
Role of the kisspeptin/KISS1 receptor system in the testicular development of mice., PMID:33543882
Neurotrophin-3 stimulates stem Leydig cell proliferation during regeneration in rats., PMID:33090725
Role of the Kisspeptin/KISS1 Receptor System in the Testicular Development of Mice., PMID:33044408
Evidence for the role of INSL3 on sperm production in boars by passive immunisation., PMID:29575065
Expression of insulin-like factor 3 hormone-receptor system in the reproductive organs of male goats., PMID:26017634
The insulin-like factor 3 (INSL3)-receptor (RXFP2) network functions as a germ cell survival/anti-apoptotic factor in boar testes., PMID:25562614
The increased number of Leydig cells by di(2-ethylhexyl) phthalate comes from the differentiation of stem cells into Leydig cell lineage in the adult rat testis., PMID:23391632
Fetal testis dysgenesis and compromised Leydig cell function in Tgfbr3 (beta glycan) knockout mice., PMID:19696014
Lysosomal acid hydrolases of the cathepsin family are novel targets of INSL3 in human thyroid carcinoma cells., PMID:19416220
Role of relaxin in human osteoclastogenesis., PMID:19416193
INSLF3-LGR8 ligand-receptor system in testes of mature rats after exposure to ethane dimethanesulphonate (short communication)., PMID:18702224
Structure of the transmembrane signal initiation site of the relaxin-like factor (RLF/INSL3)., PMID:17676766
Insulin 3-like hormone and its role in epididymo-testicular descent., PMID:17626659
Developmental expression and gene regulation of insulin-like 3 receptor RXFP2 in mouse male reproductive organs., PMID:17615407
Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate., PMID:16037377
Immunohistochemical localization of relaxin-like factor/insulin-like peptide-3 in the bovine corpus luteum., PMID:15956752
Insulin-like factor 3: where are we now?, PMID:15956750
Synthesis, conformation, receptor binding and biological activities of monobiotinylated human insulin-like peptide 3., PMID:15009530
Dynamic changes in the expression of relaxin-like factor (INSL3), cholesterol side-chain cleavage cytochrome p450, and 3beta-hydroxysteroid dehydrogenase in bovine ovarian follicles during growth and atresia., PMID:11906911
Relaxin-like factor (RLF) serum concentrations and gubernaculum RLF receptor display in relation to pre- and neonatal development of rats., PMID:11732985