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Anti-Human DEK Polyclonal Antibody

Catalog #:   PHE14601 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P35659
Overview

Catalog No.

PHE14601

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human DEK (Glu90-Lys187).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Protein DEK, DEK

Purification

Purified by antigen affinity column.

Accession

P35659

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with DEK antibody (PHE14601) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 25 kDa
    Observed MW: 25 kDa
References

The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1., PMID:38810185

Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity., PMID:38755196

The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity., PMID:37794185

The Effect of the Histone Chaperones HSPA8 and DEK on Tumor Immunity in Hepatocellular Carcinoma., PMID:36768989

Dual Fc optimization to increase the cytotoxic activity of a CD19-targeting antibody., PMID:36119088

Nuclear expression of AFF2 C-terminus is a sensitive and specific ancillary marker for DEK::AFF2 carcinoma of the sinonasal tract., PMID:35701667

Molecular Classification and Overcoming Therapy Resistance for Acute Myeloid Leukemia with Adverse Genetic Factors., PMID:35682627

SARS-CoV-2 enzyme-linked immunosorbent assays as proxies for plaque reduction neutralisation tests., PMID:35233014

DEK, a nuclear protein, is chemotactic for hematopoietic stem/progenitor cells acting through CXCR2 and Gαi signaling., PMID:35137444

Acute Myeloid Leukemia in Children: Emerging Paradigms in Genetics and New Approaches to Therapy., PMID:33439382

Role of Hepatitis E Virus Infection in North American Patients With Severe Acute Liver Injury., PMID:33259165

DEK-targeting aptamer DTA-64 attenuates bronchial EMT-mediated airway remodelling by suppressing TGF-β1/Smad, MAPK and PI3K signalling pathway in asthma., PMID:33124760

α6GABAA Receptor Positive Modulators Alleviate Migraine-like Grimaces in Mice via Compensating GABAergic Deficits in Trigeminal Ganglia., PMID:33111258

Detection of putative autoantibodies in systemic lupus erythematous using a novel native-conformation protein microarray platform., PMID:32941107

Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling., PMID:31107242

Proteomic and immunomic analysis of Schistosoma mekongi egg proteins., PMID:30009810

ELISA based on a recombinant Paragonimus heterotremus protein for serodiagnosis of human paragonimiasis in Thailand., PMID:29843786

High Levels of DEK Autoantibodies in Sera of Patients With Polyarticular Juvenile Idiopathic Arthritis and With Early Disease Flares Following Cessation of Anti-Tumor Necrosis Factor Therapy., PMID:29287303

DEK protein overexpression predicts poor prognosis in pancreatic ductal adenocarcinoma., PMID:27959420

Comparative Diagnosis of Strongyloidiasis in Immunocompromised Patients., PMID:27296387

Endothelin., PMID:26956245

Structural analysis of the synthetic Duffy Binding Protein (DBP) antigen DEKnull relevant for Plasmodium vivax malaria vaccine design., PMID:25793371

High expression of DEK predicts poor prognosis of gastric adenocarcinoma., PMID:24650035

Expression level of DEK in chronic lymphocytic leukemia is regulated by fludarabine and Nutlin-3 depending on p53 status., PMID:23052131

DEK expression in Merkel cell carcinoma and small cell carcinoma., PMID:22765016

C/EBPα and DEK coordinately regulate myeloid differentiation., PMID:22474248

Design and immunogenicity of a novel synthetic antigen based on the ligand domain of the Plasmodium vivax duffy binding protein., PMID:22116684

The TAg-RB murine retinoblastoma cell of origin has immunohistochemical features of differentiated Muller glia with progenitor properties., PMID:21862643

DEK in the synovium of patients with juvenile idiopathic arthritis: characterization of DEK antibodies and posttranslational modification of the DEK autoantigen., PMID:21280010

[A clinical and laboratory study on acute myeloid leukemia with t(6;9)(p23;q34)]., PMID:20140864

Proteome analysis of human nuclear insoluble fractions., PMID:19695025

Proteomic analysis of apoptosis related proteins regulated by proto-oncogene protein DEK., PMID:19229864

DEK proto-oncogene expression interferes with the normal epithelial differentiation program., PMID:19036808

DEK is a poly(ADP-ribose) acceptor in apoptosis and mediates resistance to genotoxic stress., PMID:18332104

Ribosomal P protein P0 as a candidate for the target antigen of anti-endothelial cell antibodies in mixed connective tissue disease., PMID:17888216

Serum from mice immunized in the context of Treg inhibition identifies DEK as a neuroblastoma tumor antigen., PMID:17397536

Cytokeratin contents of basal cell carcinoma, epidermis overlying tumour, and associated stromal amyloidosis: an immunohistochemical study., PMID:16076610

Serum antibodies to carbonic anhydrase IV in patients with autoimmune pancreatitis., PMID:15647194

Cytokeratin expression in lichen amyloidosus and macular amyloidosis., PMID:15096140

Oral contraceptive induced chorea: another condition associated with anti-basal ganglia antibodies., PMID:14742621

DEK binding to class II MHC Y-box sequences is gene- and allele-specific., PMID:12823858

Leukemia-associated fusion proteins, dek-can and bcr-abl, represent immunogenic HLA-DR-restricted epitopes recognized by fusion peptide-specific CD4+ T lymphocytes., PMID:12454745

Autoantibodies to DEK oncoprotein in systemic lupus erythematosus (SLE)., PMID:10691927

Autoantibodies to DEK oncoprotein in human inflammatory disease., PMID:10643703

Isolation and characterization of Dek, a Drosophila eph receptor protein tyrosine kinase., PMID:10356296

Autoantibodies to transcriptional regulation proteins DEK and ALY in a patient with systemic lupus erythematosus., PMID:9952027

Fas-independent and nonapoptotic cytotoxicity mediated by a human CD4(+) T-cell clone directed against an acute myelogenous leukemia-associated DEK-CAN fusion peptide., PMID:9920842

Antibodies to the DEK protein in Kikuchi's disease., PMID:9733475

Autoantibodies to DEK oncoprotein in a patient with systemic lupus erythematosus and sarcoidosis., PMID:9704652

Juvenile arthritis, HLA-A2 and binding of DEK oncogene-peptides., PMID:9684994

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human DEK Polyclonal Antibody [PHE14601]
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