Catalog No.
PHC87401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human NAT2 (Met1-Ile290).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Arylamine N-acetyltransferase 2, 2.3.1.5, Arylamide acetylase 2, N-acetyltransferase type 2, NAT-2, Polymorphic arylamine N-acetyltransferase, PNAT, NAT2, AAC2
Purification
Purified by antigen affinity column.
Accession
P11245
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Human arylamine N-acetyltransferase 2 genotype-dependent protein expression in cryopreserved human hepatocytes., PMID:32372066
The Impact of Drug Metabolism Gene Polymorphisms on Therapeutic Response and Survival in Diffuse Large B-Cell Lymphoma Patients., PMID:29629728
Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228)., PMID:28817838
Circulating intestine-derived exosomal miR-328 in plasma, a possible biomarker for estimating BCRP function in the human intestines., PMID:27571936
A proposed mechanism for the adverse effects of acebutolol: CES2 and CYP2C19-mediated metabolism and antinuclear antibody production., PMID:26408002
Effect of paracetamol use on the modification of the development of asthma by reactive oxygen species genes., PMID:23622008
Impact of interactions of cigarette smoking with NAT2 polymorphisms on rheumatoid arthritis risk in African Americans., PMID:21989592
Influence of polymorphic metabolic enzymes on biotransformation and effects of diphenylmethane diisocyanate., PMID:17676332
Description of a novel polymorphic gene encoding for arylamine N-acetyltransferase in the rhesus macaque (Macaca mulatta), a model animal for endometriosis., PMID:17460546
Arylamine N-acetyltransferase gene polymorphisms: markers for atopic asthma, serum IgE and blood eosinophil counts., PMID:16886893
[Treatment of chronic lupus erythematosus with sulfasalazine in 18 patients: reappraisal]., PMID:16840889
Evaluation of 4-aminobiphenyl-DNA adducts in human breast cancer: the influence of tobacco smoke., PMID:12727801
Association between the N-acetylation genetic polymorphism and bronchial asthma., PMID:12492617
N-Acetyltransferase genotypes as modifiers of diisocyanate exposure-associated asthma risk., PMID:11927838
Genotype of N-acetyltransferase 2 (NAT2) polymorphism in children with immunoglobulin E-mediated food allergy., PMID:11372006
Substrate-dependent regulation of human arylamine N-acetyltransferase-1 in cultured cells., PMID:10692486
Deficiency of cytosolic arylamine N-acetylation in the domestic cat and wild felids caused by the presence of a single NAT1-like gene., PMID:10022754
Expression of arylamine N-acetyltransferase in human intestine., PMID:9577349
Predisposing factors in sulphasalazine-induced systemic lupus erythematosus., PMID:9374926
Cytosolic arylamine N-acetyltransferase (NAT) deficiency in the dog and other canids due to an absence of NAT genes., PMID:9296352
Arylamine N-acetyltransferases. Expression in Escherichia coli, purification, and substrate specificities of recombinant hamster monomorphic and polymorphic isozymes., PMID:8742238
Arylarnine N-acetyltransferase as a potential biornarker in bladder cancer: fluorescent in situ hybridization and irnmunohistochernistry studies., PMID:23888894
A competitive enzyme linked immunosorbent assay for the determination of N-acetyltransferase (NAT2) phenotypes., PMID:8573631
Metabolic activation and carcinogen-DNA adduct detection in human larynx., PMID:8069857
Acetylation of serotonin in the rabbit pineal gland: an N-acetyltransferase with properties distinct from NAT1 and NAT2 is responsible., PMID:1895098
Evidence for two closely related isozymes of arylamine N-acetyltransferase in human liver., PMID:2924904
For research use only. Not for human or drug use.
