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Anti-Human PRKAR1A Polyclonal Antibody

Catalog #:   PHC82601 Specific References (26) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P10644
Overview

Catalog No.

PHC82601

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PRKAR1A (Thr106-Val381).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

cAMP-dependent protein kinase type I-alpha regulatory subunit, Tissue-specific extinguisher 1, TSE1, PRKAR1A, PKR1, PRKAR1, TSE1

Purification

Purified by antigen affinity column.

Accession

P10644

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with PRKAR1A antibody (PHC82601) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 33 kDa
    Observed MW: 33 kDa
References

From cortisol-producing adrenal adenoma to atrial myxoma, through nivolumab-induced hypophysitis: a complicated case report of Carney Complex., PMID:39217593

Lipodystrophy in methylmalonic acidemia associated with elevated FGF21 and abnormal methylmalonylation., PMID:38271099

Identification of antigenic epitopes recognized by tumor infiltrating lymphocytes in high grade serous ovarian cancer by multi-omics profiling of the auto-antigen repertoire., PMID:36943460

Sporadic superficial angiomyxomas demonstrate loss of PRKAR1A expression., PMID:34532875

Checkpoint inhibitors and radiotherapy in refractory malignant melanocytic schwannoma with Carney complex: first evidence of efficacy., PMID:34049890

Mitochondrial E3 ligase March5 maintains stemness of mouse ES cells via suppression of ERK signalling., PMID:26033541

Primary pigmented nodular adrenocortical disease: the original 4 cases revisited after 30 years for follow-up, new investigations, and molecular genetic findings., PMID:24805858

Malignant melanotic schwannian tumor: a clinicopathologic, immunohistochemical, and gene expression profiling study of 40 cases, with a proposal for the reclassification of "melanotic schwannoma"., PMID:24145644

PRKAR1A overexpression is associated with increased ECPKA autoantibody in liver fluke-associated cholangiocarcinoma: application for assessment of the risk group., PMID:22922884

PRKAR1A mutation affecting cAMP-mediated G protein-coupled receptor signaling in a patient with acrodysostosis and hormone resistance., PMID:22723333

Tissue-specific ablation of Prkar1a causes schwannomas by suppressing neurofibromatosis protein production., PMID:18953430

Detection of somatic beta-catenin mutations in primary pigmented nodular adrenocortical disease (PPNAD)., PMID:18419788

Loss of expression of protein kinase a regulatory subunit 1alpha in pigmented epithelioid melanocytoma but not in melanoma or other melanocytic lesions., PMID:18059235

Mutation of Prkar1a causes osteoblast neoplasia driven by dysregulation of protein kinase A., PMID:17932105

Primary pigmented nodular adrenocortical disease reveals insulin-like growth factor binding protein-2 regulation by protein kinase A., PMID:17280861

An active protein kinase A (PKA) is involved in meiotic arrest of rat growing oocytes., PMID:16816331

Identification and characterization of novel PKA holoenzymes in human T lymphocytes., PMID:15794744

Localization of Triton-insoluble cAMP-dependent kinase type RIbeta in rat and mouse brain., PMID:12373096

Aggregates of cAMP-dependent kinase RIalpha characterize a type of cholinergic neurons in the rat brain., PMID:11038256

Localization of cAMP-dependent signal transducers in early rat liver carcinogenesis., PMID:9541468

Cyclic AMP-dependent protein kinase (cAK) in human B cells: co-localization of type I cAK (RI alpha 2 C2) with the antigen receptor during anti-immunoglobulin-induced B cell activation., PMID:8647207

The differential response of protein kinase A to cyclic AMP in discrete brain areas correlates with the abundance of regulatory subunit II., PMID:8627334

Characterization of in-vitro-translated human regulatory and catalytic subunits of cAMP-dependent protein kinases., PMID:8119290

Cellular location and age-dependent changes of the regulatory subunits of cAMP-dependent protein kinase in rat testis., PMID:8107013

Novel isozymes of cAMP-dependent protein kinase exist in human cells due to formation of RI alpha-RI beta heterodimeric complexes., PMID:8407966

Dibutyryl cAMP treatment of neuroblastoma-glioma hybrid cells results in selective increase in cAMP-receptor protein (R-I) as measured by monospecific antibodies., PMID:11894919

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human PRKAR1A Polyclonal Antibody [PHC82601]
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