Catalog No.
PHC16801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human REG1A (Gln23-Asn166).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Lithostathine-1-alpha, Islet cells regeneration factor, ICRF, Islet of Langerhans regenerating protein, REG, Pancreatic stone protein, PSP, Pancreatic thread protein, PTP, Regenerating islet-derived protein 1-alpha, REG-1-alpha, Regenerating protein I alpha, REG1A, PSPS, PSPS1, REG
Purification
Purified by antigen affinity column.
Accession
P05451
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Identification of regenerating island-derived protein 3E in dogs., PMID:36387376
Correlation of REG1A, Claudin 7 and Ki67 expressions with tumor recurrence and prognostic factors in superficial urothelial urinary bladder carcinomas., PMID:35435371
Acute FPIES reactions are associated with an IL-17 inflammatory signature., PMID:33891982
Significance of Interleukin-6/STAT Pathway for the Gene Expression of REG Iα, a New Autoantigen in Sjögren's Syndrome Patients, in Salivary Duct Epithelial Cells., PMID:27339601
Role of regenerating gene I in claudin expression and barrier function in the small intestine., PMID:27055226
Effect of REG Iα protein on angiogenesis in gastric cancer tissues., PMID:25813126
Regenerating 1 and 3b gene expression in the pancreas of type 2 diabetic Goto-Kakizaki (GK) rats., PMID:24587207
Infliximab restores the dysfunctional matrix remodeling protein and growth factor gene expression in patients with inflammatory bowel disease., PMID:24378596
Involvement of autoimmunity to REG, a regeneration factor, in patients with primary Sjögren's syndrome., PMID:23701206
The role of proteasome beta subunits in gastrin-mediated transcription of plasminogen activator inhibitor-2 and regenerating protein1., PMID:23544109
Biomarkers for diagnosis and monitoring of celiac disease., PMID:23388848
Regenerating islet-derived 1α (Reg-1α) protein is new neuronal secreted factor that stimulates neurite outgrowth via exostosin Tumor-like 3 (EXTL3) receptor., PMID:22158612
Regenerating gene Iα is a biomarker for diagnosis and monitoring of celiac disease: a preliminary study., PMID:21867979
Circulating Reg1α proteins and autoantibodies to Reg1α proteins as biomarkers of β-cell regeneration and damage in type 1 diabetes., PMID:20972946
Expression profile of REG family proteins REG Ialpha and REG IV in advanced gastric cancer: comparison with mucin phenotype and prognostic markers., PMID:19329938
Expression and localization of regenerating gene I in a rat liver regeneration model., PMID:19284990
Administration of anti-Reg I and anti-PAPII antibodies worsens pancreatitis., PMID:19129610
Pancreatic regenerating protein I in chronic pancreatitis and aging: implications for new therapeutic approaches to diabetes., PMID:18953250
REG1A expression is an independent factor predictive of poor prognosis in patients with breast cancer., PMID:18781363
REG1A expression is an independent factor predictive of poor prognosis in patients with non-small cell lung cancer., PMID:17964685
REG Ialpha protein may function as a trophic and/or anti-apoptotic factor in the development of gastric cancer., PMID:15765400
Autoantibodies to REG, a beta-cell regeneration factor, in diabetic patients., PMID:15530148
REG I as a marker for human pancreatic acinoductular cells., PMID:15011837
Expression of the regenerating gene family in inflammatory bowel disease mucosa: Reg Ialpha upregulation, processing, and antiapoptotic activity., PMID:12425429
Isolation and characterization of rabbit single chain antibodies to human Reg Ialpha protein., PMID:12133637
Neutrophil chemoattractant 2 beta regulates expression of the Reg gene in injured gastric mucosa in rats., PMID:11113082
A recombinant rat regenerating protein is mitogenic to pancreatic derived cells., PMID:10720454
Serum reg protein level is not related to the beta cell destruction/regeneration process during early phases of diabetogenesis in type I diabetes., PMID:10526250
Expression of REG protein during cell growth and differentiation of two human colon carcinoma cell lines., PMID:10375374
pap, reg Ialpha and reg Ibeta mRNAs are concomitantly up-regulated during human colorectal carcinogenesis., PMID:10328217
Characteristics of rat pancreatic regenerating protein., PMID:9823399
Effect of reg protein on rat pancreatic ductal cells., PMID:9788538
Human pancreatic reg protein immunoenzymatic assay and molecular form in serum., PMID:9657348
Quantification of human lithostathine S2-5 forms using the antibody to the N-terminal peptide region., PMID:9598807
Ectopic expression of reg protein: A marker of colorectal mucosa at risk for neoplasia., PMID:9834348
Pancreatic lithostathine as a calcite habit modifier., PMID:8824282
Immunohistological localization of regenerating protein in ocular structures., PMID:8792364
Measurement of serum PSP/reg-protein concentration in various diseases with a newly developed enzyme-linked immunosorbent assay., PMID:8574338
High-level secretion of native rat pancreatic lithostathine in a baculovirus expression system., PMID:7667245
Purification and assay of secretory lithostathine in human pancreatic juice by fast protein liquid chromatography., PMID:7737574
Pancreatic stone protein and lactoferrin in human pancreatic juice in chronic pancreatitis., PMID:7716137
[Renal lithostathine: a new protein inhibitor of lithogenesis]., PMID:8145883
Evidence that human kidney produces a protein similar to lithostathine, the pancreatic inhibitor of CaCO3 crystal growth., PMID:1516594
[Analysis of pancreatic stone protein gene of hereditary pancreatitis]., PMID:1578808
Enzyme immunoassay and immunochemical characterization of pancreatic stone protein in human serum., PMID:1506981
Immunocytochemical demonstration of a pancreatic secretory protein of unknown function in human duodenum., PMID:1865108
Immunoreactive forms of pancreatic stone protein in six mammalian species., PMID:1886885
Identification of immunoreactive pancreatic stone protein in pancreatic stone, pancreatic tissue, and pancreatic juice., PMID:2111547
Selective precipitation of 14 kDa stone/thread proteins by concentration of pancreaticobiliary secretions: relevance to pancreatic ductal obstruction, pancreatic failure, and CF., PMID:2709264
Pancreatic stone protein: quantification in pancreatic juice by enzyme-linked immunosorbent assay and comparison with other methods., PMID:2510147