Catalog No.
PHA71701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PSTPIP1 (Met1-Cys259).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Proline-serine-threonine phosphatase-interacting protein 1, PEST phosphatase-interacting protein 1, CD2-binding protein 1, H-PIP, PSTPIP1, CD2BP1
Purification
Purified by antigen affinity column.
Accession
O43586
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Efficacy and safety of anakinra and canakinumab in PSTPIP1-associated inflammatory diseases: a comprehensive scoping review., PMID:38259483
PAPA Syndrome: Challenges in Achieving Long-Term Remission., PMID:38006373
Pan-Cancer Analysis Identifies Tumor Cell Surface Targets for CAR-T Cell Therapies and Antibody Drug Conjugates., PMID:36428765
Clinical and genetic characteristics of PSTPIP1-associated myeloid-related proteinemia inflammatory syndrome., PMID:34620178
Analysis of five cases of monogenic lupus related to primary immunodeficiency diseases., PMID:34559261
Immunological repertoire linked to PSTPIP1-associated myeloid-related inflammatory (PAMI) syndrome., PMID:34399798
A case of myeloperoxidase-antineutrophil cytoplasmic antibody and anticardiolipin antibody-positive pyogenic arthritis, pyoderma gangrenosum, acne and hidradenitis suppurativa (PAPASH) syndrome with colitis., PMID:33560194
Successful Treatment of PAPA Syndrome with Dual Adalimumab and Tacrolimus Therapy., PMID:31471736
Whole exome sequencing approach to childhood onset familial erythrodermic psoriasis unravels a novel mutation of CARD14 requiring unusual high doses of ustekinumab., PMID:31286971
Clinical and genetic association, radiological findings and response to biological therapy in seven children from Qatar with non-bacterial osteomyelitis., PMID:27860302
Alarming consequences - autoinflammatory disease spectrum due to mutations in proline-serine-threonine phosphatase-interacting protein 1., PMID:27464597
Identification of novel mutations in CD2BP1 gene in clinically proven rheumatoid arthritis patients of south India., PMID:27184502
Disease activity accounts for long-term efficacy of IL-1 blockers in pyogenic sterile arthritis pyoderma gangrenosum and severe acne syndrome., PMID:26989109
Genome-wide association study of recalcitrant atopic dermatitis in Korean children., PMID:25935106
Successful treatment of PASH syndrome with infliximab, cyclosporine and dapsone., PMID:25352307
Identification of a homozygous PSTPIP1 mutation in a patient with a PAPA-like syndrome responding to canakinumab treatment., PMID:23426477
Pyogenic arthritis, pyoderma gangrenosum, and acne syndrome (PAPA syndrome) with E250K mutation in CD2BP1 gene treated with the tumor necrosis factor inhibitor adalimumab., PMID:22513199
Pyrin Modulates the Intracellular Distribution of PSTPIP1., PMID:19584923
Classification of non-bacterial osteitis: retrospective study of clinical, immunological and genetic aspects in 89 patients., PMID:16782988
The systemic autoinflammatory diseases: inborn errors of the innate immune system., PMID:16724804
Abnormal production of tumor necrosis factor (TNF) -- alpha and clinical efficacy of the TNF inhibitor etanercept in a patient with PAPA syndrome [corrected]., PMID:15580218
Infevers: an evolving mutation database for auto-inflammatory syndromes., PMID:15300846
Regulation of the association between PSTPIP and CD2 in murine T cells., PMID:11599917