Catalog No.
PHA60001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CRX (Thr45-Pro107).
Applications
ELISA, IHC, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000 |
Target
Cone-rod homeobox protein, CRX, CORD2
Purification
Purified by antigen affinity column.
Accession
O43186
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
Purification of the copper response extracellular proteins secreted by the copper-resistant methanogen Methanobacterium bryantii BKYH and cloning, sequencing, and transcription of the gene encoding these proteins., PMID:8522526
Perfusion enhances functions of bone marrow stromal cells in three-dimensional culture., PMID:9647441
Antitumor activity of Herceptin in combination with STEALTH liposomal cisplatin or nonliposomal cisplatin in a HER2 positive human breast cancer model., PMID:10626363
Modulation of CRX transactivation activity by phosducin isoforms., PMID:10866677
Multiple phosphorylated isoforms of NRL are expressed in rod photoreceptors., PMID:11477108
The mouse Crx 5'-upstream transgene sequence directs cell-specific and developmentally regulated expression in retinal photoreceptor cells., PMID:11880494
Gene expression networks underlying retinoic acid-induced differentiation of human retinoblastoma cells., PMID:12601020
Expression of photoreceptor-associated molecules during human fetal eye development., PMID:12949469
Delayed expression of the Crx gene and photoreceptor development in the Chx10-deficient retina., PMID:14744875
Cytokine-induced activation of signal transducer and activator of transcription in photoreceptor precursors regulates rod differentiation in the developing mouse retina., PMID:15525763
Polyglutamine expansion causes neurodegeneration by altering the neuronal differentiation program., PMID:16434483
The novel combination of chlorpromazine and pentamidine exerts synergistic antiproliferative effects through dual mitotic action., PMID:18056463
Induction of functional photoreceptor phenotype by exogenous Crx expression in mouse retinal stem cells., PMID:18172122
FIZ1 is part of the regulatory protein complex on active photoreceptor-specific gene promoters in vivo., PMID:18854042
CD73, a novel cell surface antigen that characterizes retinal photoreceptor precursor cells., PMID:19515998
Generation of light-sensitive photoreceptor phenotypes by genetic modification of human adult ocular stem cells with Crx., PMID:19850845
Anatomical changes in the primary visual cortex of the congenitally blind Crx-/- mouse., PMID:20034544
A 350 bp region of the proximal promoter of Rds drives cell-type specific gene expression., PMID:20447394
Early onset and differential temporospatial expression of melanopsin isoforms in the developing chicken retina., PMID:21676907
Immunohistochemical expression of CRX in extracranial malignant small round cell tumors., PMID:22790857
The neonatal susceptibility window for inhalant allergen sensitization in the atopically predisposed canine asthma model., PMID:23181409
Electrical stimulation via a biocompatible conductive polymer directs retinal progenitor cell differentiation., PMID:24110015
Intranasal vaccination promotes detrimental Th17-mediated immunity against influenza infection., PMID:24465206
p16(INK4a) expression in retinoblastoma: a marker of differentiation grade., PMID:25499675
Methylglycol chitosan and a synthetic TLR4 agonist enhance immune responses to influenza vaccine administered sublingually., PMID:26392012
PEG modified liposomes containing CRX-601 adjuvant in combination with methylglycol chitosan enhance the murine sublingual immune response to influenza vaccination., PMID:26551346
Increased proliferation of late-born retinal progenitor cells by gestational lead exposure delays rod and bipolar cell differentiation., PMID:28050121
PHOX2B is a reliable immunomarker in distinguishing peripheral neuroblastic tumours from CNS embryonal tumours., PMID:29758594
Co-encapsulation of synthetic lipidated TLR4 and TLR7/8 agonists in the liposomal bilayer results in a rapid, synergistic enhancement of vaccine-mediated humoral immunity., PMID:31654684
NSABP B-47/NRG Oncology Phase III Randomized Trial Comparing Adjuvant Chemotherapy With or Without Trastuzumab in High-Risk Invasive Breast Cancer Negative for HER2 by FISH and With IHC 1+ or 2., PMID:31821109
Self-Adjuvanting Cancer Vaccines from Conjugation-Ready Lipid A Analogues and Synthetic Long Peptides., PMID:32960056
Pharmacokinetics and pharmacodynamics of itepekimab in healthy adults and patients with asthma: Phase I first-in-human and first-in-patient trials., PMID:34523807
Retinoic acid and taurine enhance differentiation of the human bone marrow stem cells into cone photoreceptor cells and retinal ganglion cells., PMID:34569079
The Developmental Progression of Eight Opsin Spectral Signals Recorded from the Zebrafish Retinal Cone Layer Is Altered by the Timing and Cell Type Expression of Thyroxin Receptor β2 (trβ2) Gain-Of-Function Transgenes., PMID:36351817
A synthetic TLR4 agonist significantly increases humoral immune responses and the protective ability of an MDCK-cell-derived inactivated H7N9 vaccine in mice., PMID:38990396
Pharmacokinetics and pharmacodynamics of itepekimab in adults with moderate-to-severe atopic dermatitis: Results from two terminated phase II trials., PMID:39077906
Cone-rod homeobox transcriptionally activates TCF7 to promote the proliferation of retinal pigment epithelial and retinoblastoma cells in vitro., PMID:39559312
Immunogenicity of dupilumab in adult and pediatric patients with atopic dermatitis., PMID:39588375
For research use only. Not for human or drug use.
