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Anti-Human PFAS Polyclonal Antibody

Catalog #:   PHA40301 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: O15067
Overview

Catalog No.

PHA40301

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PFAS (Met1-His153).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, 6.3.5.3, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT, Formylglycinamide ribotide amidotransferase, Phosphoribosylformylglycineamide amidotransferase, PFAS, KIAA0361

Purification

Purified by antigen affinity column.

Accession

O15067

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with PFAS antibody (PHA40301) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 19 kDa
    Observed MW: 19 kDa
References

In utero per - and polyfluoroalkyl substances (PFAS) exposure and changes in infant T helper cell development among UPSIDE-ECHO cohort participants., PMID:40489731

Unusually Broad-spectrum small-molecule sensing using a single protein scaffold., PMID:40462935

Per- and polyfluoroalkyl substances (PFAS): immunotoxicity at the primary sites of exposure., PMID:40400477

High-dimensional mediation analysis to elucidate the role of metabolites in the association between PFAS exposure and reduced SARS-CoV-2 IgG in pregnancy., PMID:40311333

Serum Concentration of Selected Per- and Polyfluoroalkyl Substances (PFAS) by Industry and Occupational Groups Among US Adult Workers, NHANES 2005-2014., PMID:40293335

[Clinical characteristics of allergic rhinitis induced by pollen in northern China]., PMID:40263659

Maternal exposure to per- and polyfluoroalkyl substances and epitope level antibody response to vaccines against measles and rubella in children from the Boston birth cohort., PMID:40215916

Forever Chemicals (PFAS): An Overview for Maternity and Pediatric Health Care Professionals., PMID:40029199

The Pharmaceutical Industry in 2024: An Analysis of the FDA Drug Approvals from the Perspective of Molecules., PMID:39942587

Prenatal per- and polyfluoroalkyl substances in relation to antibody titers and infections in childhood., PMID:39884528

High-dimensional mediation analysis to elucidate the role of metabolites in the association between PFAS exposure and reduced SARS-CoV-2 IgG in pregnancy., PMID:39763891

Perfluoroalkyl substances (PFAS) exposure and preeclampsia risk: Impaired angiogenesis through suppression of VEGF signaling., PMID:39732411

The T cell response to SARS-CoV-2 mRNA vaccine in adults with high exposure to perfluoroalkyl substances from Ronneby, Sweden., PMID:39566685

Serum per- and polyfluoroalkyl substance (PFAS) levels and health-related biomarkers in a pilot study of skiers in New England., PMID:39389198

Eosinophilic esophagitis and inhalant antigens: Pointing out the roles of allergic rhinitis, immunotherapy and biologic treatment., PMID:39386073

Antibody response to SARS-CoV-2 mRNA vaccination in Danish adults exposed to perfluoroalkyl substances (PFASs): The ENFORCE study., PMID:39326653

Biochemical and haematological effects of serum PFOA, ADV and cC6O4 in workers of a chemical company producing fluoropolymers, Italy, 2013-2022., PMID:39106565

Advancing PFAS risk assessment: Integrative approaches using agent-based modelling and physiologically-based kinetic for environmental and health safety., PMID:39050784

Childhood PFAS exposure and immunotoxicity: a systematic review and meta-analysis of human studies., PMID:38982538

Allergen Component Testing: Key in Diagnosing Atypical Pollen-Food Allergy Syndrome., PMID:38779239

Determination of in vitro immunotoxic potencies of a series of perfluoralkylsubstances (PFASs) in human Namalwa B lymphocyte and human Jurkat T lymphocyte cells., PMID:38549690

Public Health Risks of PFAS-Related Immunotoxicity Are Real., PMID:38526771

The association between per-/polyfluoroalkyl substances in serum and thyroid function parameters: A cross-sectional study on teenagers living near a Chinese fluorochemical industrial plant., PMID:38367719

Association between per- and polyfluoroalkyl substances exposure and thyroid function biomarkers among females attending a fertility clinic., PMID:38350534

Prenatal Exposure to Poly- and Perfluoroalkyl Substances (2009-2014) and Vaccine Antibody Titers of Measles, Mumps, Rubella, and Varicella in Children Four to Eight Years Old from the Healthy Start Cohort., PMID:38147368

Altered Transcriptome Response in PBMCs of Czech Adults Linked to Multiple PFAS Exposure: B Cell Development as a Target of PFAS Immunotoxicity., PMID:38112183

Early-life exposure to perfluoroalkyl substances and serum antibody concentrations towards common childhood vaccines in 18-month-old children in the Odense Child Cohort., PMID:38042520

Local nasal immunotherapy with birch pollen-galactomannan conjugate-containing ointment in mice and humans., PMID:37981502

Serum per- and polyfluoroalkyl substance concentrations and longitudinal change in post-infection and post-vaccination SARS-CoV-2 antibodies., PMID:37816422

[Research progress on pollen food allergy syndrome]., PMID:37743292

Prepandemic personal concentrations of per- and polyfluoroalkyl substances (PFAS) and other pollutants: Specific and combined effects on the incidence of COVID-19 disease and SARS-CoV-2 infection., PMID:37652221

High Exposure to Perfluoroalkyl Substances and Antibody Responses to SARS-CoV-2 mRNA Vaccine-an Observational Study in Adults from Ronneby, Sweden., PMID:37578904

Examining the impact of nanoplastics and PFAS exposure on immune functions through inhibition of secretory immunoglobin A in human breast milk., PMID:37527590

Associations of Maternal Urinary Concentrations of Phenols, Individually and as a Mixture, with Serum Biomarkers of Thyroid Function and Autoimmunity: Results from the EARTH Study., PMID:37368621

Immune response to COVID-19 vaccination in a population with a history of elevated exposure to per- and polyfluoroalkyl substances (PFAS) through drinking water., PMID:37337047

Quantifying the impact of PFOA exposure on B-cell development and antibody production., PMID:37162486

Weight of evidence evaluation for chemical-induced immunotoxicity for PFOA and PFOS: findings from an independent panel of experts., PMID:37115714

Pollen Food Allergy Syndrome in Japanese Children and Adolescents: Risk Factors and Pollen Sensitisation., PMID:36937005

Exposure to persistent organic pollutants in Danish pregnant women: Hormone levels and fetal growth indices., PMID:36921699

Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS)., PMID:36814257

Systematic review and meta-analysis of epidemiologic data on vaccine response in relation to exposure to five principal perfluoroalkyl substances., PMID:36764183

Red Blood Cell Folate Modifies the Association between Serum Per- and Polyfluoroalkyl Substances and Antibody Concentrations in U.S. Adolescents., PMID:36715557

Internal relative potency factors based on immunotoxicity for the risk assessment of mixtures of per- and polyfluoroalkyl substances (PFAS) in human biomonitoring., PMID:36628859

Critical endpoints of PFOA and PFOS exposure for regulatory risk assessment in drinking water: Parameter choices impacting estimates of safe exposure levels., PMID:36599390

A systematic evidence map of chronic inflammation and immunosuppression related to per- and polyfluoroalkyl substance (PFAS) exposure., PMID:36592815

Omalizumab is effective for a patient with pollen-food allergy syndrome who experienced intractable lip edema., PMID:36581536

Cross-sectional associations of maternal PFAS exposure on SARS-CoV-2 IgG antibody levels during pregnancy., PMID:36528042

Prenatal Exposure to Per- and Polyfluoroalkyl Substances, Maternal Thyroid Dysfunction, and Child Autism Spectrum Disorder., PMID:36415960

Relationship among airborne pollen, sensitization, and pollen food allergy syndrome in Asian allergic children., PMID:36340201

Antibody response to COVID-19 vaccines among workers with a wide range of exposure to per- and polyfluoroalkyl substances., PMID:36183490

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human PFAS Polyclonal Antibody [PHA40301]
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