Catalog No.
PHJ73701
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human DKK2 (Lys34-Ile259).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Dkk-2,hDkk-2,Dickkopf-related protein 2,DKK2,Dickkopf-2
Purification
Purified by antigen affinity column.
Accession
Q9UBU2
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Toxicity of thioacetamide and protective effects of quercetin in zebrafish (Danio rerio) larvae., PMID:34227734
DKK2 blockage-mediated immunotherapy enhances anti-angiogenic therapy of Kras mutated colorectal cancer., PMID:32559853
Rational design of peptides for identification of linear epitopes and generation of neutralizing monoclonal antibodies against DKK2 for cancer therapy., PMID:32391516
Neutralizing monoclonal antibody against Dickkopf2 impairs lung cancer progression via activating NK cells., PMID:31372243
Production and Characterization of Monoclonal and Polyclonal Antibodies Against Truncated Recombinant Dickkopf-1 as a Candidate Biomarker., PMID:30592704
DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation., PMID:29431745
Dampening of the bone formation response following repeat dosing with sclerostin antibody in mice is associated with up-regulation of Wnt antagonists., PMID:29129759
Dkk2/Frzb in the dermal papillae regulates feather regeneration., PMID:24463139
A complex interaction between Wnt signaling and TNF-α in nucleus pulposus cells., PMID:24286133
EpCAM is an endoderm-specific Wnt derepressor that licenses hepatic development., PMID:23484855
Role of non-canonical Wnt signaling in osteoblast maturation on microstructured titanium surfaces., PMID:21352958
Generation and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivo., PMID:20929859
The roles of Wnt signaling modulators Dickkopf-1 (Dkk1) and Dickkopf-2 (Dkk2) and cell maturation state in osteogenesis on microstructured titanium surfaces., PMID:20004015
Excessive ovarian stimulation up-regulates the Wnt-signaling molecule DKK1 in human endometrium and may affect implantation: an in vitro co-culture study., PMID:19955106
Mechanical stress induces Interleukin-11 expression to stimulate osteoblast differentiation., PMID:19665600
Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled., PMID:11742004