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Anti-DKK2 Polyclonal Antibody

Catalog #:   PHJ73701 Specific References (16) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q9UBU2
Overview

Catalog No.

PHJ73701

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human DKK2 (Lys34-Ile259).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Dkk-2,hDkk-2,Dickkopf-related protein 2,DKK2,Dickkopf-2

Purification

Purified by antigen affinity column.

Accession

Q9UBU2

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with DKK2 antibody (PHJ73701) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 27 kDa
    Observed MW: 27 kDa
References

Toxicity of thioacetamide and protective effects of quercetin in zebrafish (Danio rerio) larvae., PMID:34227734

DKK2 blockage-mediated immunotherapy enhances anti-angiogenic therapy of Kras mutated colorectal cancer., PMID:32559853

Rational design of peptides for identification of linear epitopes and generation of neutralizing monoclonal antibodies against DKK2 for cancer therapy., PMID:32391516

Neutralizing monoclonal antibody against Dickkopf2 impairs lung cancer progression via activating NK cells., PMID:31372243

Production and Characterization of Monoclonal and Polyclonal Antibodies Against Truncated Recombinant Dickkopf-1 as a Candidate Biomarker., PMID:30592704

DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation., PMID:29431745

Dampening of the bone formation response following repeat dosing with sclerostin antibody in mice is associated with up-regulation of Wnt antagonists., PMID:29129759

Dkk2/Frzb in the dermal papillae regulates feather regeneration., PMID:24463139

A complex interaction between Wnt signaling and TNF-α in nucleus pulposus cells., PMID:24286133

EpCAM is an endoderm-specific Wnt derepressor that licenses hepatic development., PMID:23484855

Role of non-canonical Wnt signaling in osteoblast maturation on microstructured titanium surfaces., PMID:21352958

Generation and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivo., PMID:20929859

The roles of Wnt signaling modulators Dickkopf-1 (Dkk1) and Dickkopf-2 (Dkk2) and cell maturation state in osteogenesis on microstructured titanium surfaces., PMID:20004015

Excessive ovarian stimulation up-regulates the Wnt-signaling molecule DKK1 in human endometrium and may affect implantation: an in vitro co-culture study., PMID:19955106

Mechanical stress induces Interleukin-11 expression to stimulate osteoblast differentiation., PMID:19665600

Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled., PMID:11742004

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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Distributor list

For research use only. Not for human or drug use.

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Anti-DKK2 Polyclonal Antibody [PHJ73701]
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