Catalog No.
YMA56001
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Met11-Gln325
Predicted molecular weight
37.65 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O08760
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
N-glycosylase/DNA lyase, 8-oxoguanine DNA glycosylase, 3.2.2.-, DNA-(apurinic or apyrimidinic site) lyase, AP lyase, 4.2.99.18, Ogg1
Note
For research use only.
The role of tissue persistent organic pollutants and genetic polymorphisms in patients with benign and malignant kidney tumors., PMID:38950873
Apurinic/apyrimidinic endonuclease 1 has major impact in prevention of suicidal covalent DNA-protein crosslink with apurinic/apyrimidinic site in cellular extracts., PMID:38963041
Dulaglutide reduces oxidative DNA damage and hypermethylation in the somatic cells of mice fed a high-energy diet by restoring redox balance, inflammatory responses, and DNA repair gene expressions., PMID:38963172
DNA N-glycosylases Ogg1 and EndoIII as components of base excision repair in Plasmodium falciparum organelles., PMID:38964640
Interaction of base excision repair gene polymorphism and estrogen-DNA adducts in breast cancer risk among East Asian women., PMID:38969945
The interplay of DNA damage and repair, gene expression, and mutagenesis in mammalian cells during oxidative stress., PMID:39023127
Semaglutide ameliorated autism-like behaviors and DNA repair efficiency in male BTBR mice by recovering DNA repair gene expression., PMID:39032854
Single Nucleotide Polymorphisms in APE1, hOGG1, RAD51 Genes and their Association with Radiotherapy Induced Toxicity among Head and Neck Cancer Patients., PMID:39205561
Correlation Between the Expression of DNA Damage Repair Protein OGG1 and Ubiquitination Pathway Protein STUB1 in Pediatric Neuroblastoma., PMID:39219028
The 8-oxoguanine DNA glycosylase-synaptotagmin 7 pathway increases extracellular vesicle release and promotes tumour metastasis during oxidative stress., PMID:39235072
E-cigarettes increase the risk of adenoma formation in murine colorectal cancer model., PMID:39253444
The BCL11A transcription factor stimulates the enzymatic activities of the OGG1 DNA glycosylase., PMID:39272221
Effect of aflatoxin B1 and sterigmatocystin on DNA repair genes in common carp., PMID:39277992
Comparative effects of 3,5-diiodo-L-thyronine and 3,5,3'-triiodo-L-thyronine on mitochondrial damage and cGAS/STING-driven inflammation in liver of hypothyroid rats., PMID:39301315
Human 8-oxoguanine glycosylase OGG1 binds nucleosome at the dsDNA ends and the super-helical locations., PMID:39341999
Human 8-Oxoguanine Glycosylase OGG1 Cleaves Abasic Sites and Covalently Conjugates to 3'-DNA Termini via Cysteine and Histidine Addition., PMID:39387674
Arsenic and Chromium Induced Toxicity on Zebrafish Kidney: Mixture Effects on Oxidative Stress and Involvement of Nrf2-Keap1-ARE, DNA Repair, and Intrinsic Apoptotic Pathways., PMID:39402722
Germacrone ameliorates acute lung injury induced by intestinal ischemia-reperfusion by regulating macrophage M1 polarization and mitochondrial defects., PMID:39439416
Structural basis for human OGG1 processing 8-oxodGuo within nucleosome core particles., PMID:39477986
APEX1 Polymorphisms Affect Acute Myeloid Leukemia Risk, and Its Expression Is Involved in Cell Proliferation and Differentiation., PMID:39536468
Mitochondria-Targeted DNA Repair Glycosylase hOGG1 Protects Against HFD-Induced Liver Oxidative Mitochondrial DNA Damage and Insulin Resistance in OGG1-Deficient Mice., PMID:39596235
DNA sequence and lesion-dependent mitochondrial transcription factor A (TFAM)-DNA-binding modulates DNA repair activities and products., PMID:39607700
Oxidative stress on the male reproductive organs of wild mice collected from an area contaminated by radioactive materials in Fukushima., PMID:39613832
Species-specific responses to di (2-ethylhexyl) phthalate reveal activation of defense signaling pathways in California sea lion but not in human skeletal muscle cells in primary culture., PMID:39647646
Oxidative Injury to Lung Mitochondrial DNA is a Key Contributor for the Development of Chemical Lung Injury., PMID:39651262
6-Shogaol attenuates cisplatin induced emesis by inhibiting the mtDNA-cGAS-STING signaling pathway in a rat pica model., PMID:39694431
7-Hydroxy-3-(4'-methoxyphenyl) coumarin (C12) attenuates bleomycin-induced acute lung injury and fibrosis through activation of SIRT3., PMID:39701544
Contributing factors to the oxidation-induced mutational landscape in human cells., PMID:39715760
Genetic Polymorphisms of DNA Repair Genes and their Influence on Paclitaxel based Chemotherapy Induced Toxicity Reactions in Breast Cancer Patients., PMID:39733420
E-cigarettes increase the risk of adenoma formation in murine colorectal cancer model., PMID:39786590
Targeted Activation of OGG1 Inhibits Paraptosis in Lens Epithelial Cells of Early Age-Related Cortical Cataract., PMID:39804629
Mixture effects of arsenic and chromium on erythrocytic nuclear abnormalities and expression of DNA repair, tumor suppressor and apoptotic genes in liver of zebrafish., PMID:39826661
Cancer prognosis using base excision repair genes., PMID:39828060
NEIL1: The second DNA glycosylase involved in action-at-a-distance mutations induced by 8-oxo-7,8-dihydroguanine., PMID:39848343
Oxidative damage to DNA, expression of Mt-1, and activation of repair mechanisms induced by vanadium trioxide in cultures of human lymphocytes., PMID:39897397
Expression of Neuronal Nicotinic Acetylcholine Receptor and Early Oxidative DNA Damage in Aging Rat Brain-The Effects of Memantine., PMID:40004097
Suppression of 8-oxoguanine DNA glycosylase (OGG1) activity produced positive impacts on disease severity, survival, and histopathological features of mice infected with Plasmodium berghei., PMID:40088963
Centella Asiatica Fraction-3 Enhances Antioxidant Capacity and Apoptotic Cell Death in HEK293 Kidney Cells., PMID:40160106
Oxidative damage to lung mitochondrial DNA is a key contributor to the development of chemical lung injury., PMID:40209617
Biocascade-inspired amplified oxygen vacancy effect on facet-engineered BiOI for ultrasensitive photoelectrochemical detection of 8-oxoguanine DNA glycosylase., PMID:40220491
Oxidative Stress Regulates CDH3 Expression in Lung Cancer Cells via OGG1-Mediated SP1 Binding., PMID:40227353
Consecutive skeletal muscle PGC-1α overexpression: A double-edged sword for mitochondrial health in the aging brain., PMID:40228677
OGG1S326C variant frequent in human populations facilitates inflammatory responses due to its extended interaction with DNA substrate., PMID:40343995
RBM39 Promotes Base Excision Repair to Facilitate the Progression of HCC by Stabilising OGG1 mRNA., PMID:40364450
Effects of Yoga on Gene Expression: A Systematic Review of Randomised Controlled Trials., PMID:40400827
Effects of mitoquinone and caffeic acid on spermatological parameters and OGG1/ROMO1 gene expression of post-thawed ram semen., PMID:40414026
Development and characterization of a novel NEIL1 nanobody., PMID:40440929
Gastrointestinal exposure to silica nanoparticles induced Alzheimer's disease-like neurotoxicity in mice relying on gut microbiota and modulation through TLR4/NF-κB and HDAC., PMID:40457432
DJ-1 deficiency and aging: dual drivers of retinal mitochondrial dysfunction., PMID:40475680
Genome-Wide Identification and Expression Analysis of Zona Pellucida (ZP) Gene Family in Cynoglossus semilaevis., PMID:40508155
For research use only. Not for human or drug use.
