Catalog No.
YMH73801
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Leu18-Thr131
Predicted molecular weight
14.92 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
EDL34457
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD300e antigen, Cd300e
Note
For research use only.
Monocytes immunoselected via the novel monocyte specific molecule, CD300e, differentiate into active migratory dendritic cells., PMID:17414321
Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells., PMID:20039296
CD300 heterocomplexes, a new and family-restricted mechanism for myeloid cell signaling regulation., PMID:20959446
CD300 molecule regulation of human dendritic cell functions., PMID:23072861
Bariatric Surgery Induces Disruption in Inflammatory Signaling Pathways Mediated by Immune Cells in Adipose Tissue: A RNA-Seq Study., PMID:25938420
Double-stranded RNA analog and type I interferon regulate expression of Trem paired receptors in murine myeloid cells., PMID:27141827
Antibody to CMRF35-Like Molecule 2, CD300e A Novel Biomarker Detected in Patients with Fulminant Type 1 Diabetes., PMID:27513516
The expression and function of human CD300 receptors on blood circulating mononuclear cells are distinct in neonates and adults., PMID:27595670
Helicobacter pylori Affects the Antigen Presentation Activity of Macrophages Modulating the Expression of the Immune Receptor CD300E through miR-4270., PMID:29085364
The CD300e molecule in mice is an immune-activating receptor., PMID:29358324
Immune Cell Signaling by Helicobacter pylori: Impact on Gastric Pathology., PMID:31049845
Transcriptomic Analysis and High-dimensional Phenotypic Mapping of Mononuclear Phagocytes in Mesenteric Lymph Nodes Reveal Differences Between Ulcerative Colitis and Crohn's Disease., PMID:31541232
The immune receptor CD300e negatively regulates T cell activation by impairing the STAT1-dependent antigen presentation., PMID:33020563
Polarized cytokine release from airway epithelium differentially influences macrophage phenotype., PMID:33588245
T Cell Activation, Highly Armed Cytotoxic Cells and a Shift in Monocytes CD300 Receptors Expression Is Characteristic of Patients With Severe COVID-19., PMID:33777054
Mizoribine halts kidney fibrosis in childhood IgA nephropathy: association with modulation of M2-type macrophages., PMID:36357635
Monocyte adaptations in patients with obesity during a 1.5 year lifestyle intervention., PMID:36466916
Mucosal Gene Expression in Response to SARS-CoV-2 Is Associated with Viral Load., PMID:36656015
Multiscale network analysis identifies potential receptors for SARS-CoV-2 and reveals their tissue-specific and age-dependent expression., PMID:36951513
Constructing ferroptosis-related competing endogenous RNA networks and exploring potential biomarkers correlated with immune infiltration cells in asthma using combinative bioinformatics strategy., PMID:37259023
Extracellular vesicles from human plasma dampen inflammation and promote tissue repair functions in macrophages., PMID:37272889
A reactive monocyte subset characterized by low expression of CD91 is expanded during sterile and septic inflammation., PMID:38278526
CD300e: Emerging role and mechanism as an immune-activating receptor., PMID:38677094
Exercise-downregulated CD300E acted as a negative prognostic implication and tumor-promoted role in pan-cancer., PMID:39144140
Plasma proteomic signature of risk and prognosis of frailty in the UK Biobank., PMID:39535692
CD300E+ macrophages facilitate liver regeneration after splenectomy in decompensated cirrhotic patients., PMID:39741181