Catalog No.
YHH49002
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser381-Ala605
Predicted molecular weight
26.94 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q2M3G0
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATP-binding cassette sub-family B member 5, ABCB5 P-gp, P-glycoprotein ABCB5, 7.6.2.2, ABCB5
Note
For research use only.
Cytotoxicity of 4-hydroxy-N-(naphthalen-1-yl)-2-oxo-2H-chromene-3-carboxamide in multidrug-resistant cancer cells through activation of PERK/eIF2α/ATF4 pathway., PMID:34582772
High expression of SARS-CoV2 viral entry-related proteins in human limbal stem cells., PMID:34653711
Clinical trial of ABCB5+ mesenchymal stem cells for recessive dystrophic epidermolysis bullosa., PMID:34665781
MCAM/MUC18/CD146 as a Multifaceted Warning Marker of Melanoma Progression in Liquid Biopsy., PMID:34830300
Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter., PMID:34921178
Corneal epithelial differentiation of human pluripotent stem cells generates ABCB5+ and ∆Np63α+ cells with limbal cell characteristics and high wound healing capacity., PMID:34930437
Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke., PMID:35213696
Transcriptomics, molecular docking, and cross-resistance profiling of nobiletin in cancer cells and synergistic interaction with doxorubicin upon SOX5 transfection., PMID:35344715
Heme Oxygenase-1 Has a Greater Effect on Melanoma Stem Cell Properties Than the Expression of Melanoma-Initiating Cell Markers., PMID:35408953
Functional analysis of cyantraniliprole tolerance ability mediated by ATP-binding cassette transporters in Aphis gossypii glover., PMID:35715043
Expression of the Stem Cell Marker ABCB5 in Normal and Tumor Tissues., PMID:35738589
Identification of ABCA5 among ATP-Binding Cassette Transporter Family as a New Biomarker for Colorectal Cancer., PMID:35783152
Deciphering the roles of ABCB5 in normal and cancer cells., PMID:35907754
Translational development of ABCB5+ dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers., PMID:36064604
Functional Inquiry into ATP-Binding Cassette Transporter Genes Contributing to Spirotetramat Resistance in Aphis gossypii Glover., PMID:36194468
Consecutive dosing of UVB irradiation induces loss of ABCB5 expression and activation of EMT and fibrosis proteins in limbal epithelial cells similar to pterygium epithelium., PMID:36242878
Biomarker Expression Profiling in Cervix Carcinoma Biopsies Unravels WT1 as a Target of Artesunate., PMID:36316038
Expression and clinical significance of TYRP1, ABCB5, and MMP17 in sinonasal mucosal melanoma., PMID:36373310
Utilizing MALDI-TOF MS and LC-MS/MS to access serum peptidome-based biomarkers in canine oral tumors., PMID:36517562
Comprehensive Analysis of Transcriptomics and Genetic Alterations Identifies Potential Mechanisms Underlying Anthracycline Therapy Resistance in Breast Cancer., PMID:36551262
Skin-Derived ABCB5+ Mesenchymal Stem Cells for High-Medical-Need Inflammatory Diseases: From Discovery to Entering Clinical Routine., PMID:36613507
ABCB5+ mesenchymal stromal cells therapy protects from hypoxia by restoring Ca2+ homeostasis in vitro and in vivo., PMID:36759868
Molecular Modes of Action of an Aqueous Nerium oleander Extract in Cancer Cells In Vitro and In Vivo., PMID:36838857
ABCB5+ mesenchymal stromal cells facilitate complete and durable wound closure in recessive dystrophic epidermolysis bullosa., PMID:36868990
Identification and characterization of ABC proteins in an important rice insect pest, Cnaphalocrocis medinalis unveil their response to Cry1C toxin., PMID:36894061
Kinetics of Wound Development and Healing Suggests a Skin-Stabilizing Effect of Allogeneic ABCB5+ Mesenchymal Stromal Cell Treatment in Recessive Dystrophic Epidermolysis Bullosa., PMID:37296590
The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells., PMID:37322258
ABCB5+ Limbal Epithelial Stem Cells Inhibit Developmental but Promote Inflammatory (Lymph) Angiogenesis While Preventing Corneal Inflammation., PMID:37443766
The C2H2 zinc finger transcription factor CF2-II regulates multi-insecticide resistance-related gut-predominant ABC transporters in Aphis gossypii Glover., PMID:37683749
Changes in Expression and Function of Placental and Intestinal P-gp and BCRP Transporters during Pregnancy., PMID:37685897
The β Isoform of Human ATP-Binding Cassette B5 Transporter, ABCB5β, Localizes to the Endoplasmic Reticulum., PMID:37958830
Trifloxystrobin induced developmental toxicity by disturbing the ABC transporters, carbohydrate and lipid metabolism in adult zebrafish., PMID:38000556
Evaluation of ABCB5 immunostained epithelial stem cells in oral squamous cell carcinoma, inflammatory gingival hyperplasia and normal mucosa., PMID:38073314
Identification of two novel heterodimeric ABC transporters in melanoma: ABCB5β/B6 and ABCB5β/B9., PMID:38145744
Whole genome sequencing reveals population diversity and variation in HIV-1 specific host genes., PMID:38179408
Accelerated Aging and Microsatellite Instability in Recessive Dystrophic Epidermolysis Bullosa-Associated Cutaneous Squamous Cell Carcinoma., PMID:38272206
Clinical-grade human skin-derived ABCB5+ mesenchymal stromal cells exert anti-apoptotic and anti-inflammatory effects in vitro and modulate mRNA expression in a cisplatin-induced kidney injury murine model., PMID:38274791
The noncanonical nucleotide binding site 1 of the bile salt export pump is optimized for proper function of the transporter., PMID:38328902
Potency assay to predict the anti-inflammatory capacity of a cell therapy product for macrophage-driven diseases: overcoming the challenges of assay development and validation., PMID:38441512
A conjoint analysis of renal structure and omics characteristics reveal new insight to yak high-altitude hypoxia adaptation., PMID:38729453
Prenatal opioid exposure significantly impacts placental protein kinase C (PKC) and drug transporters, leading to drug resistance and neonatal opioid withdrawal syndrome., PMID:39238930
Osteopontin, WNT3A, and ABCB5 Biomarkers Expression in Osteosarcoma Patients., PMID:39239573
The uniqueness of ABCB5 as a full transporter ABCB5FL and a half-transporter-like ABCB5β., PMID:39267923
Anti-Inflammatory and Anti-(Lymph)angiogenic Properties of an ABCB5+ Limbal Mesenchymal Stem Cell Population., PMID:39273646
The BET inhibitor JQ1 suppresses tumor survival by ABCB5-mediated autophagy in uveal melanoma., PMID:39442901
TNF-α Suppression Attenuates Limbal Stem Cell Damage in Ocular Injury., PMID:39626088
A Structural Bioinformatics-Guided Study of Adenosine Triphosphate-Binding Cassette (ABC) Transporters and Their Substrates., PMID:39852261
Caveolin 1 and 2 enhance the proliferative capacity of BCAM-positive corneal progenitors., PMID:39994275
Integrated Analysis of WES and scRNA-Seq Data Reveals the Genetic Basis of Immune Dysregulation in Unexplained Recurrent Pregnancy Loss., PMID:40066928
Integrated pan-cancer analysis revealed therapeutic targets in the ABC transporter protein family., PMID:40445912
For research use only. Not for human or drug use.
