Catalog No.
YHD38801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg253-Gln491
Predicted molecular weight
42.32 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20309
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Muscarinic acetylcholine receptor M3, CHRM3
Note
For research use only.
Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells., PMID:35955642
Impaired sweating in patients with cholinergic urticaria is linked to low expression of acetylcholine receptor CHRM3 and acetylcholine esterase in sweat glands., PMID:35967390
A Genomic Instability-Associated Prognostic Signature for Glioblastoma Patients., PMID:35977679
Examining SNP-SNP interactions and risk of clinical outcomes in colorectal cancer using multifactor dimensionality reduction based methods., PMID:35991579
Exploring the Target and Mechanism of Radix Paeoniae Alba on Sjogren's Syndrome., PMID:36017844
Identification of ceRNA regulatory network in acute pancreatitis and acute recurrent pancreatitis., PMID:36052691
Exploring the Mechanism of Wenshen Huatan Quyu Decotion for PCOS Based on Network Pharmacology and Molecular Docking Verification., PMID:36071733
Dysregulation of Circulatory Levels of lncRNAs in Parkinson's Disease., PMID:36264433
Study on Medication Rules of Traditional Chinese Medicine in Treating Constipation through Data Mining and Network Pharmacology., PMID:36267846
Role of non-neuronal cholinergic system in the early stage response of epithelial-mesenchymal transformation related markers in A549 cells induced by coal particles., PMID:36468138
Sex, Age, and Regional Differences in CHRM1 and CHRM3 Genes Expression Levels in the Human Brain Biopsies: Potential Targets for Alzheimer's Disease-related Sleep Disturbances., PMID:36475335
MiR-15b-5p inhibits castration-resistant growth of prostate cancer cells by targeting the muscarinic cholinergic receptor CHRM3., PMID:36754848
CHRM3-Associated miRNAs May Play a Role in Bile Acid-Induced Proliferation of H508 Colon Cancer Cells., PMID:36919835
Plant molecular farming-derived epidermal growth factor revolutionizes hydrogels for improving glandular epithelial organoid biofabrication., PMID:36966988
Identification of novel molecular subtypes and a signature to predict prognosis and therapeutic response based on cuproptosis-related genes in prostate cancer., PMID:37205181
Use of whole genome sequencing to determine the genetic basis of visceral myopathies including Prune Belly syndrome., PMID:37288276
High-Throughput Sequencing Data Reveal an Antiangiogenic Role of HNF4A-Mediated CACNA1A/VEGFA Axis in Proliferative Diabetic Retinopathy., PMID:37342032
A Study on the Effects of Muscarinic and Serotonergic Regulation by Bojanggunbi-tang on the Pacemaker Potential of the Interstitial Cells of Cajal in the Murine Small Intestine., PMID:37484801
Co-expression module analysis reveals high expression homogeneity for both coding and non-coding genes in sepsis., PMID:37488493
Severity of neurological Long-COVID symptoms correlates with increased level of autoantibodies targeting vasoregulatory and autonomic nervous system receptors., PMID:37689093
CHRM3 is a novel prognostic factor of poor prognosis and promotes glioblastoma progression via activation of oncogenic invasive growth factors., PMID:37744266
Itga8-Cre-mediated deletion of YAP and TAZ impairs bladder contractility with minimal inflammation and chondrogenic differentiation., PMID:37927241
Associations of genetic variations in the M3 receptor with salt sensitivity, longitudinal changes in blood pressure and the incidence of hypertension in Chinese adults., PMID:38010846
Transcriptome analysis of Schizothorax oconnori (Cypriniformes: Cyprinidae) oocytes: The role of K+ in promoting yolk globule fusion and regulating oocyte maturation., PMID:38047980
Role of ecto-5'-nucleotidase in bladder function., PMID:38198186
Targeting Farnesoid X Receptor in Tumor and the Tumor Microenvironment: Implication for Therapy., PMID:38203175
Effects of DDT and DDE on placental cholinergic receptors., PMID:38615785
Characterization of age-associated gene expression changes in mouse sweat glands., PMID:38637019
The M3 Muscarinic Acetylcholine Receptor Can Signal through Multiple G Protein Families., PMID:38641412
PM10 exposure induces bronchial hyperresponsiveness by upreguating acetylcholine muscarinic 3 receptor., PMID:39019094
[Retracted] MicroRNA‑30e inhibits adhesion, migration, invasion and cell cycle progression of prostate cancer cells via inhibition of the activation of the MAPK signaling pathway by downregulating CHRM3., PMID:39027991
Tongxieyaofang Decotion Alleviates IBS by Modulating CHRM3 and Gut Barrier., PMID:39081703
CHRM3 (rs2165870) gene polymorphism is related to postoperative vomiting in female patients undergoing laparoscopic surgery. Prospective observational study., PMID:39163289
Protective role of M3 muscarinic acetylcholine receptor in indomethacin-induced small intestinal injury., PMID:39172154
Darifenacin: a promising chitinase 3-like 1 inhibitor to tackle drug resistance in pancreatic ductal adenocarcinoma., PMID:39225813
Acute Hypobaric Hypoxia Causes Alterations in Acetylcholine-Mediated Signaling Through Varying Expression of Muscarinic Receptors in the Prefrontal Cortex and Cerebellum of Rats' Brain., PMID:39379070
The complete mitochondrial DNA of the carnivorous sponge Lycopodina hypogea is putatively complemented by microDNAs., PMID:39559335
Bone marrow mesenchymal stem cell-derived exosomal miR-181a-5p promotes M2 macrophage polarization to alleviate acute pancreatitis through ZEB2-mediated RACK1 ubiquitination., PMID:39614664
Long term Coptidis Rhizoma intake induce gastrointestinal emptying inhibition and colon barrier weaken via bitter taste receptors activation in mice., PMID:39631296
Comprehensive Gene Expression Analysis Using Human Induced Pluripotent Stem Cells Derived from Patients with Sleep Bruxism: A Preliminary In Vitro Study., PMID:39684851
Efficacy of Spray Cryotherapy on Airway Secretions in Canine Models of Chronic Bronchitis and Mechanism Insights., PMID:39809229
Muscarinic acetylcholine receptor 3 localized to primary endothelial cilia regulates blood pressure and cognition., PMID:39885271
Repurposing of dipeptidyl peptidase FDA-approved drugs in Alzheimer's disease using network pharmacology and in-silico approaches., PMID:39938415
Material basis and mechanism of Ephedra sinica in interfering with wind-chill cold., PMID:40058103
Vagal pathway activation links chronic stress to decline in intestinal stem cell function., PMID:40120585
Epitomic profiling and functional characteristics of pemphigus vulgaris autoantibody binding to keratinocyte M3 muscarinic acetylcholine receptor., PMID:40120680
Attenuation of intestinal peristalsis with age is attributed to decreased sensitivity of receptors in the enteric nervous system., PMID:40146304
Impact of temporal food restriction on sleep behavior and physiology of redheaded bunting., PMID:40389169
Transcriptional and functional profiles of muscarinic receptor-expressing neurons in primate lateral prefrontal and anterior cingulate cortices., PMID:40475401
Exploration of Asparagus racemosus Willd for Alzheimer's Disease Through Integrated Metabolomics and Network Pharmacology Analyses Targeting BACE1 Protein., PMID:40483633
For research use only. Not for human or drug use.
