Catalog No.
YHC32801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Phe380
Predicted molecular weight
42.38 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08319
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
All-trans-retinol dehydrogenase [NAD(+)] ADH4, 1.1.1.105, Alcohol dehydrogenase 2, Alcohol dehydrogenase 4, Alcohol dehydrogenase class II pi chain, ADH4, ADH2
Note
For research use only.
First description and evaluation of SNPs in the ADH and ALDH genes in a population of alcoholics in Central-West Brazil., PMID:29084628
The potential of the newly isolated thermotolerant yeast Pichia kudriavzevii RZ8-1 for high-temperature ethanol production., PMID:29154013
Genetic association of HCRTR2, ADH4 and CLOCK genes with cluster headache: a Chinese population-based case-control study., PMID:29318394
Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells., PMID:29323295
Alcohol Metabolism in the Progression of Human Nonalcoholic Steatohepatitis., PMID:29718361
Distinct Prognostic Values of Alcohol Dehydrogenase Family Members for Non-Small Cell Lung Cancer., PMID:29808834
Performance of Homologous and Heterologous Prime-Boost Immunization Regimens of Recombinant Adenovirus and Modified Vaccinia Virus Ankara Expressing an Ag85B-TB10.4 Fusion Protein against Mycobacterium tuberculosis., PMID:29847865
Modeling of Human Hepatic and Gastrointestinal Ethanol Metabolism with Kinetic-Mechanism-Based Full-Rate Equations of the Component Alcohol Dehydrogenase Isozymes and Allozymes., PMID:29847918
Acid stress induces cross-protection for cadmium tolerance of multi-stress-tolerant Pichia kudriavzevii by regulating cadmium transport and antioxidant defense system., PMID:30513442
Alcohol dehydrogenases from Proteus mirabilis contribute to alcoholic flavor., PMID:30761541
Whole transcriptome analysis of smoker palatal mucosa identifies multiple downregulated innate immunity genes., PMID:31682009
Analysis of HCRTR2, GNB3, and ADH4 Gene Polymorphisms in a Southeastern European Caucasian Cluster Headache Population., PMID:31768945
No genetic evidence for involvement of alcohol dehydrogenase genes in risk for Parkinson's disease., PMID:31806158
Candidate genes for predicting the survival of patients with gastric cancer: a study based on The Cancer Genome Atlas (TCGA) database., PMID:35117619
Production of Methionol from 3-Methylthiopropionaldehyde by Catalysis of the Yeast Alcohol Dehydrogenase Adh4p., PMID:32233408
Evaluation of Anti-proliferative Effects of Barringtonia racemosa and Gallic Acid on Caco-2 Cells., PMID:32561807
Adh4, an alcohol dehydrogenase controls alcohol formation within bacterial microcompartments in the acetogenic bacterium Acetobacterium woodii., PMID:33283462
A novel mechanism underlying alcohol dehydrogenase expression: hsa-miR-148a-3p promotes ADH4 expression via an AGO1-dependent manner in control and ethanol-exposed hepatic cells., PMID:33556337
Identification and validation of ADME genes as prognosis and therapy markers for hepatocellular carcinoma patients., PMID:33988674
A stemness-based eleven-gene signature correlates with the clinical outcome of hepatocellular carcinoma., PMID:34147074
Multi-omics integration reveals the hepatoprotective mechanisms of ursolic acid intake against chronic alcohol consumption., PMID:34215920
Drug metabolism-related eight-gene signature can predict the prognosis of gastric adenocarcinoma., PMID:34773716
No significant association between SNPs in the CLOCK and ADH4 genes and susceptibility to cluster headaches: A systematic review and meta-analysis., PMID:35437765
miR-29c-3p promotes alcohol dehydrogenase gene cluster expression by activating an ADH6 enhancer., PMID:35868429
Distinctive Metabolism-Associated Gene Clusters That Are Also Prognostic in Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma., PMID:36199423
Identification and validation of a tyrosine metabolism-related prognostic prediction model and characterization of the tumor microenvironment infiltration in hepatocellular carcinoma., PMID:36341373
The prognostic role of fatty acid metabolism-related genes in patients with gastric cancer., PMID:36388036
Alcohol dehydrogenase 4 is a TP53-associated gene signature for the prediction of prognosis in hepatocellular carcinoma., PMID:36419756
Screening for Lipid-Metabolism-Related Genes and Identifying the Diagnostic Potential of ANGPTL6 for HBV-Related Early-Stage Hepatocellular Carcinoma., PMID:36421714
Novel Insights into MEG3/miR664a-3p/ADH4 Axis and Its Possible Role in Hepatocellular Carcinoma from an in Silico Perspective., PMID:36553522
Data-independent acquisition proteomics reveals circulating biomarkers of coronary chronic total occlusion in humans., PMID:36561774
Microvascular and macrovascular complications of type 2 diabetes mellitus: Exome wide association analyses., PMID:37033211
ACE2 negatively regulates the Warburg effect and suppresses hepatocellular carcinoma progression via reducing ROS-HIF1α activity., PMID:37215979
An inflammation-associated ferroptosis signature optimizes the diagnosis, prognosis evaluation and immunotherapy options in hepatocellular carcinoma., PMID:37248957
Comparative Analysis of Different Proteins and Metabolites in the Liver and Ovary of Local Breeds of Chicken and Commercial Chickens in the Later Laying Period., PMID:37762699
A novel metabolism-related gene signature in patients with hepatocellular carcinoma., PMID:38025761
Proteomic and Metabolomic Signatures of Diet Quality in Young Adults., PMID:38337712
Identification of metabolism-related key genes as potential biomarkers for pathogenesis of immune thrombocytopenia., PMID:38641637
Analysis of alcohol-metabolizing enzymes genetic variants and RAR/RXR expression in patients diagnosed with fetal alcohol syndrome: a case-control study., PMID:38886650
Global Gene Expression Profiling and Bioinformatics Analysis Reveal Downregulated Biomarkers as Potential Indicators for Hepatocellular Carcinoma., PMID:38911766
Proteomics profiling and association with cardiorenal complications in type 2 diabetes subtypes in Asian population., PMID:39059739
ADH4-a potential prognostic marker for hepatocellular carcinoma with possible immune-related implications., PMID:39090641
TSA attenuates the progression of c-Myc-driven hepatocarcinogenesis by pAKT-ADH4 pathway., PMID:39187747
[Analysis of genetic association between exon polymorphisms of ADH4 and ADH7 and risky drinking behavior of alcoholic liver disease]., PMID:39710484
Characterization of human alcohol dehydrogenase 4 and aldehyde dehydrogenase 2 as enzymes involved in the formation of 5-carboxylpirfenidone, a major metabolite of pirfenidone., PMID:39884816
Finding Potential Drug Targets for Pre-Eclampsia Using Mendelian Randomisation and Colocalisation Analysis., PMID:40028697
Integrative multi-omics analysis reveals molecular signatures of central obesity in children., PMID:40044886
Investigation of mitochondrial DNA methylation-related prognostic biomarkers in hepatocellular carcinoma using The Cancer Genome Atlas (TCGA) database., PMID:40224972
Impact of DNA methylation on digestive and metabolic gene expression in red pandas (Ailurus fulgens) during the transition from milk to bamboo diet., PMID:40275147
Exploring causal plasma protein level ratios and potential drug targets for depression: A proteomics Mendelian randomization study., PMID:40499826
For research use only. Not for human or drug use.
