Catalog No.
YHB67401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu29-Arg81
Predicted molecular weight
34.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95484
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Claudin-9, CLDN9
Claudin-9 (CLDN9) promotes gastric cancer progression by enhancing the glycolysis pathway and facilitating PD-L1 lactylation to suppress CD8+ T cell anti-tumor immunity., PMID:40458308
Complete omission of exon 21 from Slc12a2 transcripts in mice results in hearing loss., PMID:40295800
CLDN9 and hsa-miR-4496 as non-invasive biomarkers for gastric cancer detection., PMID:40198459
Molecular characterization and biomarker discovery in gastric cancer progression through transcriptome meta-analysis., PMID:39447404
Identification of potential inhibitors for drug resistance in acute lymphoblastic leukemia through differentially expressed gene analysis and in silico screening., PMID:39025197
Claudins and hepatocellular carcinoma., PMID:38185042
Expression of Claudin-9 (CLDN9) in Breast Cancer, the Clinical Significance in Connection with Its Subcoat Anchorage Proteins ZO-1 and ZO-3 and Impact on Drug Resistance., PMID:38137355
The correlation among Claudin-9, Tyrosine kinase-2, and Signal transducers and activators of transcription-3 expressions in non-functioning pituitary adenoma and invasiveness., PMID:38131177
Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells., PMID:37873357
Identification of key claudin genes associated with survival prognosis and diagnosis in colon cancer through integrated bioinformatic analysis., PMID:37799140
Pharmacological Activity of Matrine in Inhibiting Colon Cancer Cells VM Formation, Proliferation, and Invasion by Downregulating Claudin-9 Mediated EMT Process and MAPK Signaling Pathway., PMID:37719361
Epigenetic and Tumor Microenvironment for Prognosis of Patients with Gastric Cancer., PMID:37238607
DNA-methylation and immunological response in medication overuse headache., PMID:36786322
Antibody specificity against highly conserved membrane protein Claudin 6 driven by single atomic contact point., PMID:36505931
A single mutation in the E2 glycoprotein of hepatitis C virus broadens the claudin specificity for its infection., PMID:36424447
Claudin‑9 is a novel prognostic biomarker for endometrial cancer., PMID:36129146
Transcriptional and Epigenetic Bioinformatic Analysis of Claudin-9 Regulation in Gastric Cancer., PMID:39296813
Claudin-9 constitutes tight junctions of folliculo-stellate cells in the anterior pituitary gland., PMID:34737342
Variants of human CLDN9 cause mild to profound hearing loss., PMID:34265170
A glycolysis-related gene signature predicts prognosis of patients with esophageal adenocarcinoma., PMID:33234735
Identification of claudin-2, -6, -11 and -14 as prognostic markers in human breast carcinoma., PMID:31934042
Transcriptome Analysis Identifies an Attenuated Local Immune Response in Invasive Nonfunctioning Pituitary Adenomas., PMID:31565884
Claudin-9 structures reveal mechanism for toxin-induced gut barrier breakdown., PMID:31434788
Claudin-9 enhances the metastatic potential of hepatocytes via Tyk2/Stat3 signaling., PMID:31418417
A truncating CLDN9 variant is associated with autosomal recessive nonsyndromic hearing loss., PMID:31175426
Identification of claudin‑1, ‑3, ‑7 and ‑8 as prognostic markers in human laryngeal carcinoma., PMID:31115553
Claudin expression during early postnatal development of the murine cochlea., PMID:29368643
Displaying Tetra-Membrane Spanning Claudins on Enveloped Virus-Like Particles for Cancer Immunotherapy., PMID:29131519
TLR2 activation induced by H. pylori LPS promotes the differential expression of claudin-4, -6, -7 and -9 via either STAT3 and ERK1/2 in AGS cells., PMID:29031421
Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology., PMID:28904640
Humanisation of a claudin-1-specific monoclonal antibody for clinical prevention and cure of HCV infection without escape., PMID:28360099
NDRG1 is important to maintain the integrity of airway epithelial barrier through claudin-9 expression., PMID:28191699
Tongxinluo Reverses the Hypoxia-suppressed Claudin-9 in Cardiac Microvascular Endothelial Cells., PMID:26879018
A spontaneous metastasis model reveals the significance of claudin-9 overexpression in lung cancer metastasis., PMID:26669782
Identification of Variants of Hepatitis C Virus (HCV) Entry Factors in Patients Highly Exposed to HCV but Remaining Uninfected: An ANRS Case-Control Study., PMID:26571379
Expression of claudin-5, -7, -8 and -9 in cervical carcinoma tissues and adjacent non-neoplastic tissues., PMID:26464708
Selection of a hepatitis C virus with altered entry factor requirements reveals a genetic interaction between the E1 glycoprotein and claudins., PMID:25820616
Overexpression of the cell adhesion molecule claudin-9 is associated with invasion in pituitary oncocytomas., PMID:25281028
Functional analysis of claudin-6 and claudin-9 as entry factors for hepatitis C virus infection of human hepatocytes by using monoclonal antibodies., PMID:23864633
Isolate-dependent use of claudins for cell entry by hepatitis C virus., PMID:23775920
Innate immunity and non-Hodgkin's lymphoma (NHL) related genes in a nested case-control study for gastric cancer risk., PMID:23028900
The mRNA of claudins is expressed in the endolymphatic sac epithelia., PMID:21871748
Characterization and evaluation of the antitumour activity of a dual-targeting monoclonal antibody against claudin-3 and claudin-4., PMID:21115905
Claudin-6, 7, or 9 overexpression in the human gastric adenocarcinoma cell line AGS increases its invasiveness, migration, and proliferation rate., PMID:20874001
Distribution and expression pattern of claudins 6, 7, and 9 in diffuse- and intestinal-type gastric adenocarcinomas., PMID:19960275
A claudin-9-based ion permeability barrier is essential for hearing., PMID:19696885
Effect of claudins 6 and 9 on paracellular permeability in MDCK II cells., PMID:18784328
Prevention of murine experimental corneal trauma by epigenetic events regulating claudin 6 and claudin 9., PMID:18661270
The tight junction proteins claudin-1, -6, and -9 are entry cofactors for hepatitis C virus., PMID:18234789
Claudin-6 and claudin-9 function as additional coreceptors for hepatitis C virus., PMID:17804490
For research use only. Not for human or drug use.
