Catalog No.
PMJ64101
Species reactivity
Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse ESM1 (Tyr24-Arg184).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
ESM-1,ESM1,Endothelial cell-specific molecule 1
Purification
Purified by antigen affinity column.
Accession
Q9QYY7
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Combination of anlotinib with immunotherapy enhanced both anti-angiogenesis and immune response in high-grade serous ovarian cancer., PMID:40260248
Serum Endocan Levels in Children with Acute Rheumatic Fever., PMID:39348324
B cell lymphoma 6 promotes hepatocellular carcinoma progression by inhibiting tumor infiltrating CD4+T cell cytotoxicity through ESM1., PMID:38956432
Novel specific anti-ESM1 antibodies overcome tumor bevacizumab resistance by suppressing angiogenesis and metastasis., PMID:37715566
MASP2 inhibition by narsoplimab suppresses endotheliopathies characteristic of transplant-associated thrombotic microangiopathy: in vitro and ex vivo evidence., PMID:37191586
Endothelial-Specific Molecule 1 Inhibition Lessens Productive Angiogenesis and Tumor Metastasis to Overcome Bevacizumab Resistance., PMID:36428773
Plasma protein-based signature predicts distant metastasis and induction chemotherapy benefit in Nasopharyngeal Carcinoma., PMID:32863958
Elevated plasma endocan and BOC in heart failure patients decrease after heart transplantation in association with improved hemodynamics., PMID:32651845
Endocan as a marker of microvascular inflammation in kidney transplant recipients., PMID:30755622
Large-Scale Single-Cell RNA-Seq Reveals Molecular Signatures of Heterogeneous Populations of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells., PMID:29986945
Endocan Blockade Suppresses Experimental Ocular Neovascularization in Mice., PMID:29450540
Loss of endothelial cell-specific molecule 1 promotes the tumorigenicity and metastasis of prostate cancer cells through regulation of the TIMP-1/MMP-9 expression., PMID:28108731
ESM1 mediates NGFR-induced invasion and metastasis in murine oral squamous cell carcinoma., PMID:27683113
Radiogenomics Monitoring in Breast Cancer Identifies Metabolism and Immune Checkpoints as Early Actionable Mechanisms of Resistance to Anti-angiogenic Treatment., PMID:27474395
Endocan, Novel Potential Biomarker for Systemic Sclerosis: Results of a Pilot Study., PMID:26331941
Markers of endothelial dysfunction in patients with non-alcoholic fatty liver disease and coronary artery disease., PMID:25587619
Increased expression of endocan in arthritic synovial tissues: effects of adiponectin on the expression of endocan in fibroblast-like synoviocytes., PMID:25483913
Vascular changes in the developing rat retina in response to hypoxia., PMID:25433125
Identification of fibroblast growth factor-18 as a molecule to protect adult articular cartilage by gene expression profiling., PMID:24577103
Endocan elicits severe vascular inflammatory responses in vitro and in vivo., PMID:24446198
Detection and mechanism of action of ESM-1 in rat kidney transplantation under various immune states., PMID:23850961
Clinicopathological correlation of endocan expression and survival in epithelial ovarian cancer., PMID:23708323
Overexpression of endothelial cell specific molecule-1 (ESM-1) in gastric cancer., PMID:20383661
Targeting the angiopoietin (Ang)/Tie-2 pathway in the crosstalk between acute myeloid leukaemia and endothelial cells: studies of Tie-2 blocking antibodies, exogenous Ang-2 and inhibition of constitutive agonistic Ang-1 release., PMID:20050812
Hierarchical normalized cuts: unsupervised segmentation of vascular biomarkers from ovarian cancer tissue microarrays., PMID:20425992
Efficient long-term and high-yielded production of a recombinant proteoglycan in eukaryotic HEK293 cells using a membrane-based bioreactor., PMID:18261977
Vascular endocan is preferentially expressed in tumor endothelium., PMID:16956626
Endocan or endothelial cell specific molecule-1 (ESM-1): a potential novel endothelial cell marker and a new target for cancer therapy., PMID:16168566
Overexpression of endocan induces tumor formation., PMID:14522939
Endothelial cell specific molecule-1--a newly identified protein in adipocytes., PMID:12778364
High tumour contamination of leukaphereses in patients with small cell carcinoma of the lung: a comparison of immunocytochemistry and RT-PCR., PMID:11742493
Characterization of the secreted form of endothelial-cell-specific molecule 1 by specific monoclonal antibodies., PMID:11025405
For research use only. Not for human or drug use.
