Catalog No.
YHA85602
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln274-Ser495
Predicted molecular weight
27.29 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O60266
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Adenylate cyclase type 3, 4.6.1.1, ATP pyrophosphate-lyase 3, Adenylate cyclase type III, AC-III, Adenylate cyclase, olfactive type, Adenylyl cyclase 3, AC3, ADCY3, KIAA0511
Note
For research use only.
Identifying molecular pathways and candidate genes associated with knob traits by transcriptome analysis in the goose (Anser cygnoides)., PMID:34099774
Epigenome-Wide Study Identified Methylation Sites Associated with the Risk of Obesity., PMID:34207686
Molecular mechanism of reproductive toxicity induced by Tripterygium Wilfordii based on network pharmacology., PMID:34232166
ALDH2, ADCY3 and BCMO1 polymorphisms and lifestyle-induced traits are jointly associated with CAD risk in Chinese Han people., PMID:34481002
The potential cytotoxic effects of urban particle matter on olfaction., PMID:34636368
Regulation of Brain Primary Cilia Length by MCH Signaling: Evidence from Pharmacological, Genetic, Optogenetic, and Chemogenic Manipulations., PMID:34665407
Weighted gene co-expression network analysis to identify key modules and hub genes associated with paucigranulocytic asthma., PMID:34727921
Molecular modelling of novel ADCY3 variant predicts a molecular target for tackling obesity., PMID:34821371
The Spectrum of Genetic Variants Associated with the Development of Monogenic Obesity in Qatar., PMID:35026759
NF-κB-Related Metabolic Gene Signature Predicts the Prognosis and Immunotherapy Response in Gastric Cancer., PMID:35036435
REEP6 knockout leads to defective β-adrenergic signaling in adipocytes and promotes obesity-related metabolic dysfunction., PMID:35150731
Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis., PMID:35721542
Chronic intermittent hypoxia impacts the olfactory nervous system in an age-dependent manner: pilot study., PMID:35780199
RNA modification-related variants in genomic loci associated with body mass index., PMID:35879730
Effects of berberine hydrochloride on immune response in the crab Charybdis japonica., PMID:35953779
Energy Trade-off and 4 Extreme Human Body Types., PMID:36413496
Next-generation sequencing of 12 obesity genes in a Portuguese cohort of patients with overweight and obesity., PMID:36775011
Association of Plant-Based and High-Protein Diets with a Lower Obesity Risk Defined by Fat Mass in Middle-Aged and Elderly Persons with a High Genetic Risk of Obesity., PMID:36839421
GWAS-Identified Variants for Obesity Do Not Influence the Risk of Developing Multiple Myeloma: A Population-Based Study and Meta-Analysis., PMID:37047000
Understanding the Genetics of Early-Onset Obesity in a Cohort of Children From Qatar., PMID:37329217
The Effects of the Levels of Hypoxia in the Olfactory Nervous System in Mouse Model., PMID:37350017
Hypoxia sensing requires H2S-dependent persulfidation of olfactory receptor 78., PMID:37406126
Illuminating (HTLV-1)-induced adult T-cell leukemia/lymphoma transcriptomic signature: A systems virology approach., PMID:37832654
Adenylate cyclase 3: a potential genetic link between obesity and major depressive disorder., PMID:37955134
CLCF1 inhibits energy expenditure via suppressing brown fat thermogenesis., PMID:38190531
Postnatal Dynamic Ciliary ARL13B and ADCY3 Localization in the Mouse Brain., PMID:38334651
Mendelian Randomization Analysis Identifies Inverse Causal Relationship between External Eating and Metabolic Phenotypes., PMID:38674857
Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function., PMID:38684889
GDF15 controls primary cilia morphology and function thereby affecting progenitor proliferation., PMID:38719753
The Molecular Basis of Olfactory Dysfunction in COVID-19 and Long COVID., PMID:38749402
Whole Exome Sequencing Revealed Paternal Inheritance of Obesity-related Genetic Variants in a Family with an Exclusively Breastfed Infant., PMID:38915195
Protein-coding mutation in Adcy3 increases adiposity and alters emotional behaviors sex-dependently in rats., PMID:38916175
The association between dietary, physical activity and the DNA methylation of PPARGC1A, HLA-DQA1 and ADCY3 in pregnant women with gestational diabetes mellitus: a nest case-control study., PMID:39060963
Central regulation of feeding and body weight by ciliary GPR75., PMID:39137039
Dietary "Beigeing" Fat Contains More Phosphatidylserine and Enhances Mitochondrial Function while Counteracting Obesity., PMID:39329159
Neuronal LAMP2A-mediated reduction of adenylyl cyclases induces acute neurodegenerative responses and neuroinflammation after ischemic stroke., PMID:39341961
Ciliary localization of GPR75 promotes fat accumulation in mice., PMID:39352389
Functional Evaluation of a Novel Homozygous ADCY3 Variant Causing Childhood Obesity., PMID:39519366
Protein-coding mutation in Adcy3 increases adiposity and alters emotional behaviors sex-dependently in rats., PMID:39632398
Network-based meta-analysis and confirmation of genes ATP1A2, FXYD1, and ADCY3 associated with cAMP signaling in breast tumors compared to corresponding normal marginal tissues., PMID:39707785
Effects of Gene-Lifestyle Interaction on Obesity Among Students., PMID:39766774
[Association between ADCY3 gene polymorphism and the effects of high-intensity interval training on body composition]., PMID:39780573
Signal Transduction Pathway Mediating Carotid Body Dependent Sympathetic Activation and Hypertension by Chronic Intermittent Hypoxia., PMID:39844350
A novel golgi related genes based correlation prognostic index can better predict the prognosis of glioma and responses to immunotherapy., PMID:39976877
Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single-cell RNA sequencing analysis., PMID:40017120
Association between polymorphisms of the adenylate cyclase 3 gene rs2241759 and the effect of high-intensity interval training on blood lipid profiles., PMID:40231066
A mutation in the transmembrane domain of Adenylate cyclase 3 impairs enzymatic function to cause sex-specific depression- and anxiety-like behaviors and food seeking in a rat model., PMID:40236087
Regulation of perinatal estrogen levels on primordial follicle formation and activation in mouse., PMID:40261643
GPR45 modulates Gαs at primary cilia of the paraventricular hypothalamus to control food intake., PMID:40472089
A Mutation in the Transmembrane Domain of Adenylate Cyclase 3 Impairs Enzymatic Function to Cause Sex-Specific Depression- and Anxiety-Like Behaviors and Food Seeking in a Rat Model., PMID:40492272
For research use only. Not for human or drug use.
