Catalog No.
YHJ94901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln70-Leu237
Predicted molecular weight
22.15 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UMR7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C-type lectin domain family 4 member A, C-type lectin DDB27, C-type lectin superfamily member 6, Dendritic cell immunoreceptor, Lectin-like immunoreceptor, CD367, CLEC4A, CLECSF6, DCIR, LLIR, HDCGC13P
Keratins 2 and 4/13 in reconstituted human skin are reciprocally regulated by retinoids binding to nuclear receptor RARalpha., PMID:20456496
An RPE cell line as a useful in vitro model for studying retinoic acid receptor beta: expression and affinity., PMID:18673301
Activation of retinoic acid receptor-dependent transcription by organochlorine pesticides., PMID:15589975
Critical role of the H6-H7 loop in the conformational adaptation of all-trans retinoic acid and synthetic retinoids within the ligand-binding site of RARalpha., PMID:10828828
Differential effects of several retinoid receptor-selective ligands on squamous differentiation and apoptosis in airway epithelial cells., PMID:10805076
Retinoic acid inhibits nitric oxide synthase-2 expression through the retinoic acid receptor-alpha., PMID:10772914
Retinoic acid receptors regulate expression of retinoic acid 4-hydroxylase that specifically inactivates all-trans retinoic acid in human keratinocyte HaCaT cells., PMID:9740237
Retinoic acid inhibits CD40 + interleukin-4-mediated IgE production in vitro., PMID:9716600
Both retinoic acid receptors alpha (RARalpha) and gamma (RARgamma) are able to initiate mouse upper-lip skin glandular metaplasia., PMID:9699718
H11-H12 loop retinoic acid receptor mutants exhibit distinct trans-activating and trans-repressing activities in the presence of natural or synthetic retinoids., PMID:9649304
Evidence for the involvement of both retinoic acid receptor- and retinoic X receptor-dependent signaling pathways in the induction of tissue transglutaminase and apoptosis in the human myeloma cell line RPMI 8226., PMID:9516142
Expression of retinoid nuclear receptor superfamily members in human hair follicles and its implication in hair growth., PMID:9298126
Suprabasal expression of a dominant-negative RXR alpha mutant in transgenic mouse epidermis impairs regulation of gene transcription and basal keratinocyte proliferation by RAR-selective retinoids., PMID:9000050
Structural determinants of the ligand-binding site of the human retinoic acid receptor alpha., PMID:7727406
Endogenous retinoic acid receptor (RAR)-retinoid X receptor (RXR) heterodimers are the major functional forms regulating retinoid-responsive elements in adult human keratinocytes. Binding of ligands to RAR only is sufficient for RAR-RXR heterodimers to confer ligand-dependent activation of hRAR beta 2/RARE (DR5)., PMID:7852380
Physicochemical parameters affecting the charcoal adsorption assay for quantitative retinoid-binding measurement., PMID:7515595
Purification and functional characterization of the ligand-binding domain from the retinoic acid receptor alpha: evidence that sulfhydryl groups are involved in ligand-receptor interactions., PMID:8241133
Characterization and purification of human retinoic acid receptor-gamma 1 overexpressed in the baculovirus-insect cell system., PMID:1332684
In vitro binding of retinoids to the nuclear retinoic acid receptor alpha., PMID:2162635