Catalog No.
YHB14901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr508-Lys724
Predicted molecular weight
27.87 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75330
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Hyaluronan mediated motility receptor, Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility, CD168, HMMR, IHABP, RHAMM
Monotropein attenuates renal cell carcinoma cell progression and M2 macrophage polarization by weakening NF-κB., PMID:39776402
Prognosis and tumor microenvironment in pseudohypoxic pheochromocytoma/paraganglioma., PMID:39694932
N-CADHERIN+/CD168- subpopulation determines therapeutic variations of UC-MSCs for cardiac repair after myocardial infarction., PMID:39533355
Study on the therapeutic effect of sintilimab combined with modified DCF regimen on advanced gastric cancer and its impact on Th1/Th2 immune balance., PMID:38958648
Receptor for hyaluronan-mediated motility (RHAMM) defines an invasive niche associated with tumor progression and predicts poor outcomes in breast cancer patients., PMID:37186300
Visualization of macrophage subsets in the development of the fetal human inner ear., PMID:36159857
IL-1 receptor-associated kinase 1 participates in the modulation of the NLRP3 inflammasome by tumor-associated macrophages in hepatocellular carcinoma., PMID:35837195
Identification and validation of Osteopontin and receptor for hyaluronic acid-mediated motility (RHAMM, CD168) for potential immunotherapeutic significance of in lung squamous cell carcinoma., PMID:35334357
Secretion of BMP-2 by tumor-associated macrophages (TAM) promotes microcalcifications in breast cancer., PMID:34983451
The mannose receptor (CD206) identifies a population of colonic macrophages in health and inflammatory bowel disease., PMID:34608184
RHAMM in liver metastases of stage IV colorectal cancer with mismatch-repair proficient status correlates with tumor budding, cytotoxic T-cells and PD-1/PD-L1., PMID:34051513
PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung., PMID:33576873
Overexpression of CD168 is related to poor prognosis in oral squamous cell carcinoma., PMID:33386685
Hyaluronic Acid (HA) Receptors and the Motility of Schwann Cell(-Like) Phenotypes., PMID:32560323
CD44 and RHAMM expression patterns in the human developing lung., PMID:32311697
Stage-related PD-L1 expression in Kaposi sarcoma tumor microenvironment., PMID:32310306
Reversing tumor stemness via orally targeted nanoparticles achieves efficient colon cancer treatment., PMID:31200145
Single cell transcriptomic analysis of human mesenchymal stem cells reveals limited heterogeneity., PMID:31068579
Hyaluronan Disrupts Cardiomyocyte Organization within 3D Fibrin-Based Hydrogels., PMID:30878203
[Interleukin-17-mediated inflammation promotes nonalcoholic fatty liver disease in mice with regulation of M1-type macrophage polarization]., PMID:30669784
HOTAIR alleviates ox-LDL-induced inflammatory response in Raw264.7 cells via inhibiting NF-κB pathway., PMID:30402866
Prognostic significance of receptor for hyaluronan acid-mediated motility (CD168) in acute pediatric leukemias - assessment of clinical outcome, post induction, end of treatment and minimal residual disease., PMID:30370408
The Receptor for Hyaluronan-Mediated Motility (CD168) promotes inflammation and fibrosis after acute lung injury., PMID:30098420
Extracellular Matrix Components HAPLN1, Lumican, and Collagen I Cause Hyaluronic Acid-Dependent Folding of the Developing Human Neocortex., PMID:30078576
The Role of CD44 and RHAMM in Endometrial (Endometrioid Type) Cancer: An Immunohistochemical Study., PMID:29734248
Redox Responsive Hyaluronic Acid Nanogels for Treating RHAMM (CD168) Over-expressive Cancer, both Primary and Metastatic Tumors., PMID:28529647
The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells., PMID:27659531
Expression of the hyaluronan-mediated motility receptor RHAMM in tumor budding cells identifies aggressive colorectal cancers., PMID:26351067
Combined expressional analysis, bioinformatics and targeted proteomics identify new potential therapeutic targets in glioblastoma stem cells., PMID:26295306
Multiparameter analysis of homogeneously R-CHOP-treated diffuse large B cell lymphomas identifies CD5 and FOXP1 as relevant prognostic biomarkers: report of the prospective SAKK 38/07 study., PMID:26071053
Receptor for hyaluronic acid-mediated motility (RHAMM, CD168) expression is prognostically important in both nodal negative and nodal positive large cell lung cancer., PMID:25731190
A case of cervical cancer expressed three mRNA variant of Hyaluronan-mediated motility receptor., PMID:24966934
Deregulation of hyaluronan synthesis, degradation and binding promotes breast cancer., PMID:24092768
Accelerated uptake of VWF/platelet complexes in macrophages contributes to VWD type 2B-associated thrombocytopenia., PMID:23945153
Hydrogels that mimic developmentally relevant matrix and N-cadherin interactions enhance MSC chondrogenesis., PMID:23733927
Hyaluronan (HA) interacting proteins RHAMM and hyaluronidase impact prostate cancer cell behavior and invadopodia formation in 3D HA-based hydrogels., PMID:23166824
Toll-like receptor 2 (TLR2), transforming growth factor-β, hyaluronan (HA), and receptor for HA-mediated motility (RHAMM) are required for surfactant protein A-stimulated macrophage chemotaxis., PMID:22948158
RHAMM/HMMR (CD168) is not an ideal target antigen for immunotherapy of acute myeloid leukemia., PMID:22532518
The effects of covalently immobilized hyaluronic acid substrates on the adhesion, expansion, and differentiation of embryonic stem cells for in vitro tissue engineering., PMID:21871660
Hyaluronan-coated nanoparticles: the influence of the molecular weight on CD44-hyaluronan interactions and on the immune response., PMID:21745506
How does a protein with dual mitotic spindle and extracellular matrix receptor functions affect tumor susceptibility and progression?, PMID:21655434
Prognostic impact of CD168 expression in gastric cancer., PMID:21435222
In situ RHAMM protein expression in acute myeloid leukemia blasts suggests poor overall survival., PMID:21274712
Definition of a target for immunotherapy and results of the first Peptide vaccination study in chronic lymphocytic leukemia., PMID:20970674
Bilateral testicular metastasis from prostatic adenocarcinoma mimicking an intertubular pattern of seminoma and expressing Rhamm., PMID:20479558
Coexpression of CD44 variant isoforms and receptor for hyaluronic acid-mediated motility (RHAMM, CD168) is an International Prognostic Index and C-MYC gene status-independent predictor of poor outcome in diffuse large B-cell lymphomas., PMID:19857547
RHAMM (CD168) is overexpressed at the protein level and may constitute an immunogenic antigen in advanced prostate cancer disease., PMID:19724689
Frequency of expression of RHAMM/CD168 in Egyptian patients with CML., PMID:21057560
Androgen receptor regulates CD168 expression and signaling in prostate cancer., PMID:18174258
The hyaluronan receptors CD44 and Rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cells., PMID:17392272
For research use only. Not for human or drug use.
