Catalog No.
YVV19906
Expression system
E. coli
Species
Dengue virus type 2 (DENV-2)
Protein length
Met281-Ala722
Predicted molecular weight
50.97 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P29990
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Genome polyprotein, Capsid protein C, Core protein, Protein prM, Peptide pr, Small envelope protein M, Matrix protein, Envelope protein E, Non-structural protein 1, NS1, Non-structural protein 2A, NS2A, Serine protease subunit NS2B, Flavivirin protease NS2B regulatory subunit, Non-structural protein 2B, Serine protease NS3, 3.4.21.91, 3.6.1.15, 3.6.4.13, Flavivirin protease NS3 catalytic subunit, Non-structural protein 3, Non-structural protein 4A, NS4A, Peptide 2k, Non-structural protein 4B, NS4B, RNA-directed RNA polymerase NS5, 2.1.1.56, 2.1.1.57, 2.7.7.48, Non-structural protein 5
Antiviral in vitro activity of a novel dichlorinated tyrosine methyl ester derivative against the infection of two flaviviruses of public health concern, dengue and zika virus., PMID:40450991
Clinico-genomic study reveals association of dengue virus genome high frequency mutations with dengue disease severity., PMID:40436903
Role of c-ABL in DENV-2 Infection and Actin Remodeling in Vero Cells., PMID:40362443
Genomic hotspots in the DENV-2 serotype (E, NS4B, and NS5 genes) are associated with dengue disease severity in the endemic region of India., PMID:40299925
Seropositivity to Dengue, Zika, Yellow Fever, and West Nile Viruses in Senegal, West Africa., PMID:40207881
Broad-spectrum antiviral ferruginol analog affects the viral proteins translation and actin remodeling during dengue virus infection., PMID:40043781
Darunavir inhibits dengue virus replication by targeting the hydrophobic pocket of the envelope protein., PMID:40024350
miRNome analysis reveals mir-155-5p as a protective factor to dengue infection in a resistant Thai cohort., PMID:39976655
RT-RPA Assisted CRISPR/Cas12a Based One-Pot Rapid and Visual Detection of the Pan-Dengue Virus., PMID:39949262
E2 Ubiquitin-Conjugating Enzymes Regulates Dengue Virus-2 Replication in Aedes albopictus., PMID:39770712
Genetic diversity of dengue virus circulating in the Philippines (2014-2019) and comparison with dengue vaccine strains., PMID:39700304
Dominance of dengue virus serotype-2 in Pakistan (2023-2024): Molecular characterization of the envelope gene and exploration of antiviral targets., PMID:39557198
Long term T cell response and safety of a tetravalent dengue vaccine in healthy children., PMID:39420169
Effects of the oxoaporphine alkaloid hernandonine on dengue virus. Evidence for its mechanisms of action., PMID:39232285
Efficacy and safety of Butantan-DV in participants aged 2-59 years through an extended follow-up: results from a double-blind, randomised, placebo-controlled, phase 3, multicentre trial in Brazil., PMID:39116904
Multi-epitope peptide vaccines targeting dengue virus serotype 2 created via immunoinformatic analysis., PMID:39085250
Epidemiological, virological and clinical characterization of a Dengue/Zika outbreak in the Caribbean region of Costa Rica 2017-2018., PMID:38988809
Development of optical and electrochemical immunodevices for dengue virus detection., PMID:38780022
Antiviral drug discovery: Pyrimidine entry inhibitors for Zika and dengue viruses., PMID:38718623
Identifying citrus limonoids as a potential fusion inhibitor of DENV-2 virus through its in silico study and FTIR analysis., PMID:38680655
NOD2 Responds to Dengue Virus Type 2 Infection in Macrophage-like Cells Interacting with MAVS Adaptor and Affecting IFN-α Production and Virus Titers., PMID:38668261
A 2D-proteomic analysis identifies proteins differentially regulated by two different dengue virus serotypes., PMID:38594317
E-Protein Protonation Titration-Induced Single-Particle Chemical Force Spectroscopy for Microscopic Understanding and pI Estimation of Infectious DENV., PMID:38512319
Low-temperature culture enhances production of flavivirus virus-like particles in mammalian cells., PMID:38416210
Live, Attenuated, Tetravalent Butantan-Dengue Vaccine in Children and Adults., PMID:38294972
Inhibition of dengue viruses by N-methylcytisine thio derivatives through targeting viral envelope protein and NS2B-NS3 protease., PMID:38242331
Exploring the viral protease inhibitor space driven by consensus scoring-based virtual screening., PMID:38050479
Circulation of Dengue Virus Serotype 1 Genotype V and Dengue Virus Serotype 2 Genotype III in Tocantins State, Northern Brazil, 2021-2022., PMID:38005815
Clinical, Virological, and Immunological Features in Cosmopolitan Genotype DENV-2-Infected Patients during a Large Dengue Outbreak in Sri Lanka in 2017., PMID:37696512
Genetic Characterization of the Dengue Virus Type 3 Genotype I Prevailing in Dhaka, Bangladesh, 2021., PMID:37603293
Dengue virus serotype 2 genotype III evolution during the 2019 outbreak in Mato Grosso, Midwestern Brazil., PMID:37544570
Serotype-associated immune response and network immunoclusters in children and adults during acute Dengue virus infection., PMID:37542834
Dengue Virus Infection Alters Inter-Endothelial Junctions and Promotes Endothelial-Mesenchymal-Transition-Like Changes in Human Microvascular Endothelial Cells., PMID:37515125
Liang-Ge-San inhibits dengue virus serotype 2 infection by reducing caveolin1-induced cytoplasmic heat shock protein 70 translocation into the plasma membrane., PMID:37506573
Epitope prediction and designing of receptor inhibitor of Dengue Envelope Protein: An in silico approach., PMID:37417165
Blockade-of-Binding Activities toward Envelope-Associated, Type-Specific Epitopes as a Correlative Marker for Dengue Virus-Neutralizing Antibody., PMID:37409936
Experimental Dengue Virus Type 4 Infection Increases the Expression of MicroRNAs-15/16, Triggering a Caspase-Induced Apoptosis Pathway., PMID:37367040
N-Butanol Extract of Glycyrrhizae Radix et Rhizoma Inhibits Dengue Virus through Targeting Envelope Protein., PMID:37259408
Comparative Virucidal Activities of Essential Oils and Alcohol-Based Solutions against Enveloped Virus Surrogates: In Vitro and In Silico Analyses., PMID:37241897
Isolation and Genetic Evolution of Dengue Virus from the 2019 Outbreak in Xishuangbanna, Yunnan Province, China., PMID:37184906
Transgene-induced cell death following dengue-2 virus infection in Aedes aegypti., PMID:37045866
Evolutionary dynamics of dengue virus in India., PMID:37011104
AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5., PMID:36905944
Immunogenicity and safety of concomitant and sequential administration of yellow fever YF-17D vaccine and tetravalent dengue vaccine candidate TAK-003: A phase 3 randomized, controlled study., PMID:36888687
Efficient generation and characterization of chimeric dengue viral-like particles., PMID:36878035
Evaluation of an Immunoglobulin E Capture Enzyme-Linked Immunosorbent Assay for the Early Diagnosis of Dengue., PMID:36862827
Dengue Virus Increases the Expression of TREM-1 and CD10 on Human Neutrophils., PMID:36811498
Development of novel antiviral peptides against dengue serotypes 1-4., PMID:36739680
The dengue virus 4 component of NIAID's tetravalent TV003 vaccine drives its innate immune signature., PMID:36734144
Recombinant Protein Mimicking the Antigenic Structure of the Viral Surface Envelope Protein Reinforces Induction of an Antigen-Specific and Virus-Neutralizing Immune Response Against Dengue Virus., PMID:36723792