Catalog No.
YHC31701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Val780
Predicted molecular weight
87.34 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Concentration
0.22 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08237
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.02% NLS.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATP-dependent 6-phosphofructokinase, muscle type, PFK-M, Phosphofructo-1-kinase isozyme A, 6-phosphofructokinase type A, PFK-A, PFKM, PFKX, ATP-PFK, Phosphohexokinase
Note
For research use only.
Exon Skipping of Ste20-Like Kinase Enhances Glycolysis and Tumor Progression by Activating Enolase 1-Mediated Phosphoenolpyruvate Production. [YHC31701]
Non-metabolic functions of phosphofructokinase-1 orchestrate tumor cellular invasion and genome maintenance under bevacizumab therapy., PMID:35608632
PFKM inhibits doxorubicin-induced cardiotoxicity by enhancing oxidative phosphorylation and glycolysis., PMID:35804014
Association of PFKM gene polymorphisms and susceptibility to cryptorchidism in a Chinese Han population., PMID:35838787
Skeletal-Muscle-Specific Overexpression of Chrono Leads to Disruption of Glucose Metabolism and Exercise Capacity., PMID:36013411
Black Ginger (Kaempferia parviflora) Extract Enhances Endurance Capacity by Improving Energy Metabolism and Substrate Utilization in Mice., PMID:36145222
Differential expression of aerobic oxidative metabolism-related proteins in diabetic urinary exosomes., PMID:36187097
Bone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM., PMID:36253358
Exploring metabolism in scleroderma reveals opportunities for pharmacological intervention for therapy in fibrosis., PMID:36304460
A proteomic approach to identify biomarkers of foal meat quality: A focus on tenderness, color and intramuscular fat traits., PMID:36345099
Mining of chicken muscle growth genes and the function of important candidate gene RPL3L in muscle development., PMID:36407004
RNAi screening reveals a synthetic chemical-genetic interaction between ATP synthase and PFK1 in cancer cells., PMID:36601784
Associative analysis of multi-omics data indicates that acetylation modification is widely involved in cigarette smoke-induced chronic obstructive pulmonary disease., PMID:36714109
Comparative Proteomic Analysis of Glycolytic and Oxidative Muscle in Pigs., PMID:36833290
Senecavirus A-induced glycolysis facilitates virus replication by promoting lactate production that attenuates the interaction between MAVS and RIG-I., PMID:37126525
Bioinformatics identification of prognostic genes and potential interaction analysis in renal cell carcinoma., PMID:37180655
Novel Drug Targets for Atrial Fibrillation Identified Through Mendelian Randomization Analysis of the Blood Proteome., PMID:37212950
Aspirin induces immunogenic cell death and enhances cancer immunotherapy in colorectal cancer., PMID:37290325
RELA governs a network of islet-specific metabolic genes necessary for beta cell function., PMID:37311878
Cardiac Molecular Remodeling by Anticancer Drugs: Doxorubicin Affects More Metabolism While Mitoxantrone Impacts More Autophagy in Adult CD-1 Male Mice., PMID:37371499
Scraping Therapy Improved Muscle Regeneration through Regulating GLUT4/Glycolytic and AMPK/mTOR/4EBP1 Pathways in Rats with Lumbar Multifidus Injury., PMID:37397163
Analysis of the role of glucose metabolism-related genes in dilated cardiomyopathy based on bioinformatics., PMID:37559624
Transcriptome profiling of A549 non-small cell lung cancer cells in response to Trichinella spiralis muscle larvae excretory/secretory products., PMID:37601754
Phosphofructokinase family genes in grass carp: Molecular identification and tissue-specific expression in response to glucose, insulin and glucagon., PMID:37673204
Synergistic suppressive effects on triple-negative breast cancer by the combination of JTC-801 and sodium oxamate., PMID:37970352
Harpagide inhibits the TNF-α-induced inflammatory response in rat articular chondrocytes by the glycolytic pathways for alleviating osteoarthritis., PMID:38142643
NAT10 mediated ac4C acetylation driven m6A modification via involvement of YTHDC1-LDHA/PFKM regulates glycolysis and promotes osteosarcoma., PMID:38233839
Blockade of C5aR1 resets M1 via gut microbiota-mediated PFKM stabilization in a TLR5-dependent manner., PMID:38331868
Glutaminase potentiates the glycolysis in esophageal squamous cell carcinoma by interacting with PDK1., PMID:38353358
RBBP7, regulated by SP1, enhances the Warburg effect to facilitate the proliferation of hepatocellular carcinoma cells via PI3K/AKT signaling., PMID:38368381
[Effect and mechanism of Yueju Pills on breast cancer induced by DMBA in rats]., PMID:38403319
The characterization of protein lactylation in relation to cardiac metabolic reprogramming in neonatal mouse hearts., PMID:38479452
A Ratiometric Catalog of Protein Isoform Shifts in the Cardiac Fetal Gene Program., PMID:38645170
Nano-Se exhibits limited protective effect against heat stress induced poor breast muscle meat quality of broilers compared with other selenium sources., PMID:38972969
Distinct maturation, glucose metabolism, and inflammatory function of human monocytes-derived IDECs mediated by anti-IgE and Pam3CSK4 alone or in combination., PMID:39086490
Phosphofructokinase-1 in Cancer: A Promising Target for Diagnosis and Therapy., PMID:39171598
Genetics of Exertional Heat Illness: Revealing New Associations and Expanding Heterogeneity., PMID:39457051
The Role of PI3K/AKT/HIF-1α Pathway in the Effect of Nano-TiO2 on Lactate Production in TM4 Cells., PMID:39533807
rTM reprograms macrophages via the HIF-1α/METTL3/PFKM axis to protect mice against sepsis., PMID:39549085
TPM4 condensates glycolytic enzymes and facilitates actin reorganization under hyperosmotic stress., PMID:39622827
Gene ontology defines pre-post- hatch energy dynamics in the complexus muscle of broiler chickens., PMID:39633257
Exploring variances in meat quality between Qingyuan partridge chicken and Cobb broiler: Insights from combined multi-omics analysis., PMID:39721276
Activated DRP1 promotes mitochondrial fission and induces glycolysis in ATII cells under hyperoxia., PMID:39725939
Chloroquine Suppresses Colorectal Cancer Progression via Targeting CHKA and PFKM to inhibit the PI3K/AKT Pathway and the Warburg Effect., PMID:39990656
Knockdown of SESN2 Exacerbates Cerebral Ischemia-Reperfusion Injury Through Enhancing Glycolysis via the mTOR/HIF-1α Pathway., PMID:40032632
Identification and validation of transcriptome-wide association study-derived genes as potential druggable targets for osteoarthritis., PMID:40079200
Glucagon-like peptide-1 receptor signaling activation in alveolar type II cells enhances lung development in neonatal rats exposed to hyperoxia., PMID:40080965
Gua Sha Alleviates Radiculitis-Induced Pain Via HIF-1α-Mediated Metabolic Reprogramming Pathway in Rats., PMID:40130025
PFKM-Mediated Glycolysis: A Pathway for ASIC1 to Enhance Cell Survival in the Acidic Microenvironment of Liver Cancer., PMID:40149892
Expanding the clinical phenotype and understanding the biochemical consequences of Muscle Glycogen Synthase Deficiency (GSD0B)., PMID:40398079
TXNIP participates in the pathogenesis of PCOS by regulating glycolysis in granulosa cells., PMID:40499496
For research use only. Not for human or drug use.
