Catalog No.
YMJ23501
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Met73-Lys208
Predicted molecular weight
17.58 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8K4Z2
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2, Peroxisomal protein, PeP, Irisin, Fndc5, Frcp2, Pep
Note
For research use only.
Combined Treatment of Metformin and Resveratrol Promotes Myogenesis Through Increased Irisin Release in C2C12 Cells., PMID:40011370
FNDC5/Irisin exacerbates APAP-induced acute liver injury through activating JNK/NF-κB and inflammatory response., PMID:40016523
Identification of candidate nsSNPs of the human FNDC5 gene and their structural and functional consequences using in silico analysis., PMID:40044721
Beta(β)-sitosterol attenuates Chronic Unpredictable Stress (CUS) Induced Testicular Damage in the Experimental Rat Model., PMID:40044991
Irisin and liraglutide combination therapy mitigates myocardial reperfusion injury in obese rats: Role of endoplasmic reticulum stress and apoptosis., PMID:40049268
Exercise induced irisin mitigates hepatitis in anabolic-androgenic steroids treated rats via modulation of PGC-1-α/PPARγ/Nrf2 and NRF2/NF-κB/TLR4 signaling., PMID:40054305
Prenatal irisin is inversely related to the term placental telomere length., PMID:40057798
Irisin decreases follicle development in cattle and inhibits theca cell steroidogenesis through focal adhesion kinase signaling., PMID:40062916
The Effects of Obesity, Six Weeks of Aerobic Training, and Cold Water Exposure on the Expression of FNDC5 and UCP1 Genes in Male Wistar Rats., PMID:40071055
Fndc5/irisin mediates the benefits of aerobic exercise intervention on aging-associated sarcopenia in mice., PMID:40080339
Irisin reverses high-fat diet-induced metabolic dysfunction via activation of brown adipose tissue in mice., PMID:40082597
Irisin alleviates steroid-induced vascular dysfunction by regulating the αVβ5-c-Abl-Caveolin-1 signaling pathway., PMID:40086515
Irisin attenuates liver fibrosis by regulating energy metabolism and HMGB1/β-catenin signaling in hepatic stellate cells., PMID:40101858
Examining a role for irisin in treating cerebral ischemia., PMID:40135689
Effects of Different Intensities of Endurance Training on Neurotrophin Levels and Functional and Cognitive Outcomes in Post-Ischaemic Stroke Adults: A Randomised Clinical Trial., PMID:40141452
The Regulatory Effects of Exercise and Metformin on Biomarkers in Obesity: A Focus on Uric Acid, Irisin, Adiponutrin, Adropin, and Copeptin., PMID:40142210
Irisin prevents visceral hypersensitivity and colonic hyperpermeability in a rat model of irritable bowel syndrome., PMID:40154794
The Complex Interplay of Irisin Levels, Low Birth Weight, and Blood Pressure in Prepubescent Children., PMID:40165348
Irisin Alleviates Impaired Mitochondrial Fusion via Enhancing PKA/SIRT3/mTOR Pathway in Hepatic Steatosis., PMID:40170593
Aerobic Exercise Restores Hippocampal Neurogenesis and Cognitive Function by Decreasing Microglia Inflammasome Formation Through Irisin/NLRP3 Pathway., PMID:40192010
Acute effects of high-intensity interval exercise plus whole-body vibration on bone turnover markers, BDNF, irisin, and neurocognitive performance in postmenopausal women., PMID:40209895
Irisin Regulates Microglia M1/M2 Polarization and Promotes Autophagy Through the Sirt3 Pathway to Alleviate POCD., PMID:40214830
Persian Gulf brown seaweed extracts showing anti-obesity potency on adipogenic differentiation in human adipose-derived mesenchymal stem cells and obese male rats., PMID:40222851
Consecutive skeletal muscle PGC-1α overexpression: A double-edged sword for mitochondrial health in the aging brain., PMID:40228677
Physical activity in Alzheimer's disease prevention: Sex differences and the roles of BDNF and irisin., PMID:40228745
Transcriptional Intermediary Factor 1γ-Induced Irisin in Skeletal Muscle Attenuates Renal Fibrosis in Diabetic Nephropathy., PMID:40235186
Effect of regular exercise on ocular inflammation and mitochondrial biogenesis in experimental Alzheimer's disease model., PMID:40235325
Irisin and its role in fracture healing: A comparative study with hyaluronic acid and platelet-rich plasma in a rat model., PMID:40235411
Irisin mitigates osteoporotic-associated bone loss and gut dysbiosis in ovariectomized mice by modulating microbiota, metabolites, and intestinal barrier integrity., PMID:40241040
Cytokine response to resistance exercise in children with excess adiposity and Prader-Willi syndrome., PMID:40243109
Systemic effect of combined functional overload and endurance-type swimming exercise on whole body metabolism in mice., PMID:40248969
Keto Acids Attenuate Skeletal Muscle Atrophy in Chronic Kidney Disease via Inhibiting Pyroptosis and Upregulating Irisin Precursor FNDC5 Expression., PMID:40272551
High Serum Levels of Irisin, Visfatin and Adiponectin as Potential Independent Risk Factors for Diabetic Nephropathy Progression in Patients With Type 2 Diabetes Mellitus., PMID:40294981
Irisin Is a Potential Novel Biomarker and Therapeutic Target Against Kidney Diseases., PMID:40318104
Irisin suppressed the progression of TBI via modulating AMPK/MerTK/autophagy and SYK/ROS/inflammatory signaling., PMID:40320408
Are breast milk and serum irisin levels affected by the BMI and nutritional status? A prospective observational study., PMID:40325267
From Skeletal Muscle to Myocardium: Molecular Mechanisms of Exercise-Induced Irisin Regulation of Cardiac Fibrosis., PMID:40332022
Clinical significance of serum irisin, 25(OH)D3 and albumin in older adults with chronic disease and sarcopenia., PMID:40377817
Cardiovascular System is Influenced by Skeletal Muscle-derived Extracellular Vesicles, Myokines and MicroRNAs Based on Interorgan Communication: A Systematic Review., PMID:40386050
Muscle-derived factor alleviated cognitive impairment caused by intestinal ischemia-reperfusion., PMID:40388874
Examination of hemorheological and exerkine concentrations at four-week whole body vibration exercise in obese women: A pilot study., PMID:40392016
The therapeutic potential of irisin in alleviating acute lung injury via inflammation and ferroptosis modulation., PMID:40406908
Investigating Anti-Tumor Effects of Irisin in Cervical Cancer Cells: Cell Viability, Migration, and Tumor-Associated Macrophage Polarization., PMID:40415369
Potential effect of Irisin on sarcopenia: a systematic review., PMID:40420047
Role and Functions of Irisin: A Perspective on Recent Developments and Neurodegenerative Diseases., PMID:40427436
The Association Between Myokines, Inflammation, and Nutritional Status in Patients with Multiple Sclerosis., PMID:40427596
Irisin and its role in the reproductive physiology: a review., PMID:40435081
Irisin Protects Against Diabetic Cardiomyopathy by Suppressing Ferroptosis., PMID:40455667
Gestational fish oil supplementation in high-fat diet induces sex-specific myokine changes in weanling offspring., PMID:40459971
Physiological and psychological responses to five-day fasting., PMID:40479627
For research use only. Not for human or drug use.
