Catalog No.
EHD12902
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Ser301
Predicted molecular weight
34.96 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P15813
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD1d, CD1D, Antigen-presenting glycoprotein CD1d, R3G1
Uremic toxin receptor NR1H3 contributes to hyperlipidemia- and chronic kidney disease-accelerated vascular inflammation, which is partially suppressed by novel YBX2 anti-ROS pathway., PMID:40505347
The critical role of Id2 gene in mesenchymal stem cell therapy for colitis through regulating immune response and microbiota., PMID:40450917
NKT Hybridoma Cell Stimulation Assays to Evaluate Glycolipid Specificity and Processing., PMID:40402450
Exosomes Derived From BMMSCs Promote B10 Cell Differentiation but Not IL-10 Production., PMID:40384415
The balance between conventional and unconventional T follicular helper cells influences autoreactive B cell responses., PMID:40252220
CD1d-iNKT Axis in Infectious Diseases: Lessons Learned From the Past., PMID:40243400
Vorinostat restores iNKT cell functionality in aggressive cholangiocarcinoma., PMID:40101585
HSV-1 UL56 protein recruits cellular NEDD4-family ubiquitin ligases to suppress CD1d expression and NKT cell function., PMID:40047437
Pulchinenoside B4 alleviates DSS-induced colitis by inhibiting CD1d-dependent NLRP3 inflammasome activation in macrophages., PMID:39854876
PRDM1 Is a Key Regulator of the NKT-cell Central Memory Program and Effector Function., PMID:39820712
Myeloid antigen-presenting cells in neurodegenerative diseases: a focus on classical and non-classical MHC molecules., PMID:39720231
The α glycolipid rules the NKT cell TCR., PMID:39714312
CAR-iNKT cell therapy: mechanisms, advantages, and challenges., PMID:39662251
Highly Selective Cytokine Induction of Nitrated Lipid-Modified α-GalCer Derivatives Demonstrating High Binding Affinity to the Lipid Antigen Presenting Molecule CD1d., PMID:39632752
Diverse NKT cells regulate early inflammation and neurological outcomes after cardiac arrest and resuscitation., PMID:39630883
Identification of Functional Immune Biomarkers in Breast Cancer Patients., PMID:39596374
IFN-γ-dependent regulation of intestinal epithelial homeostasis by NKT cells., PMID:39580798
TNF-expressing CD1d+ monocytes are associated with the activation of CD4- CD8- T cells in patients with Chagas cardiomyopathy., PMID:39570155
Optimizing iNKT-driven immune responses against cancer by modulating CD1d in tumor and antigen presenting cells., PMID:39561929
α-GalCer sp2-iminoglycolipid analogs as CD1d-dependent iNKT modulators: Evaluation of their immunotherapeutic potential in murine models of asthma and autoimmune hepatitis., PMID:39561498
Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d., PMID:39363106
The surveillance of viral infections by the unconventional Type I NKT cell., PMID:39355244
CAR-redirected natural killer T cells demonstrate superior antitumor activity to CAR-T cells through multimodal CD1d-dependent mechanisms., PMID:39354225
Over-activation of iNKT cells aggravate lung injury in bronchopulmonary dysplasia mice., PMID:39342744
TIPE2 protein restrains invariant NKT activation and protects against immune-mediated hepatitis in mice., PMID:39325944
Ligand-induced segregation from large cell-surface phosphatases is a critical step in γδ TCR triggering., PMID:39276348
Cellular Output and Physicochemical Properties of the Membrane-Derived Vesicles Depend on Chemical Stimulants., PMID:39250321
Insights into the CD1 lipidome., PMID:39238636
Looking ahead to targeting macrophages by CAR T- or NK-cells in blood cancers., PMID:39235181
Lipidomic scanning of self-lipids identifies headless antigens for natural killer T cells., PMID:39141352
Tartrolon D induces immunogenic cell death in melanoma., PMID:39097071
NKT cells promote Th1 immune bias to dengue virus that governs long-term protective antibody dynamics., PMID:39088280
Features of the CD1 gene family in rodents and the uniqueness of the immune system of naked mole-rat., PMID:39075541
Rationally Designed Highly Potent NKT Cell Agonists with Different Cytokine Selectivity through Hydrogen-Bond Interaction., PMID:39031770
Unravelling metabolic factors impacting iNKT cell biology in obesity., PMID:39029630
Immune phenotyping in a pediatric multicenter transplant study: Suitability of a preformulated dry-antibody panel system., PMID:39013208
Cutting Edge: Redundant Roles for MHC Class II-, CD1d-, and MR1-restricted T Cells in Clearing Bartonella Infection., PMID:38984869
Effective suppression of tumor growth and hepatic metastasis of neuroblastoma by NKT-stimulatory phenyl glycolipid., PMID:38959605
A structural perspective of how T cell receptors recognize the CD1 family of lipid antigen-presenting molecules., PMID:38945451
Characterizing Common and Rare Variations in Nontraditional Glycemic Biomarkers Using Multivariate Approaches on Multiancestry ARIC Study., PMID:38869630
CD1d affects the proliferation, migration, and apoptosis of human papillary thyroid carcinoma TPC-1 cells via regulating MAPK/NF-κB signaling pathway., PMID:38868316
A Glycolipid-Peptide-Hapten Tricomponent Conjugate Vaccine Generates Durable Antihapten Antibody Responses in Mice., PMID:38829263
Studying the cellular basis of small bowel enteropathy using high-parameter flow cytometry in mouse models of primary antibody deficiency., PMID:38803492
Human CD4+ iNKT cell adoptive immunotherapy induces anti-tumour responses against CD1d-negative EBV-driven B lymphoma., PMID:38736328
Immunotherapy with an antibody against CD1d modulates neuroinflammation in an α-synuclein transgenic model of Lewy body like disease., PMID:38622654
Ox-LDL-induced CD80+ macrophages expand pro-atherosclerotic NKT cells via CD1d in atherosclerotic mice and hyperlipidemic patients., PMID:38586879
Role of sulfatide-reactive vNKT cells in promoting lung Treg cells via dendritic cell modulation in asthma models., PMID:38460658
CD1d protects against hepatocyte apoptosis in non-alcoholic steatohepatitis., PMID:38438948
Regulatory B Cells-Immunopathological and Prognostic Potential in Humans., PMID:38391970
NKT cells in the antitumor response: the β version?, PMID:38357925
For research use only. Not for human or drug use.
