Anti-CARD9 Polyclonal Antibody

Catalog No.

PHJ55401

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CARD9 (Asp26-Leu283).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

hCARD9,CARD9,Caspase recruitment domain-containing protein 9

Purification

Purified by antigen affinity column.

Accession

Q9H257

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

The importance of Fcγ and C-type lectin receptors in host immune responses during Pneumocystis pneumonia., PMID:39745390

Deletion of Card9 eliminates the detrimental facets of mycobacterial adjuvants., PMID:39386804

A unique serum IgG glycosylation signature predicts development of Crohn's disease and is associated with pathogenic antibodies to mannose glycan., PMID:39080486

A Critical Role for CARD9 in Intestinal Microbiota Modulation and Colorectal Malignancies., PMID:36624940

Triptolide promotes autophagy to inhibit mesangial cell proliferation in IgA nephropathy via the CARD9/p38 MAPK pathway., PMID:35733381

CARD9 Mediates Pancreatic Islet Beta-Cell Dysfunction Under the Duress of Hyperglycemic Stress., PMID:35362297

[CARD9 Mutation in a Patient with Candida albicans Meningoencephalitis; A Case Report]., PMID:34666665

Genetic Analysis of a Cohort of 275 Patients with Hyper-IgE Syndromes and/or Chronic Mucocutaneous Candidiasis., PMID:34390440

Contribution of mycobiota to the pathogenesis of spondyloarthritis., PMID:34166798

TREM (Triggering Receptor Expressed on Myeloid Cells)-1 Inhibition Attenuates Neuroinflammation via PKC (Protein Kinase C) δ/CARD9 (Caspase Recruitment Domain Family Member 9) Signaling Pathway After Intracerebral Hemorrhage in Mice., PMID:33947214

Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves' Disease., PMID:33912135

Anti-TROVE2 Antibody Determined by Immune-Related Array May Serve as a Predictive Marker for Adalimumab Immunogenicity and Effectiveness in RA., PMID:33763493

Gut mycobiota modulates antifungal antibody-mediated immunity., PMID:33707767

Local farming of gut fungi protects against dangerous imports., PMID:33705697

Human gut mycobiota tune immunity via CARD9-dependent induction of anti-fungal IgG antibodies., PMID:33548172

Priming with FLO8-deficient Candida albicans induces Th1-biased protective immunity against lethal polymicrobial sepsis., PMID:33154574

Effect of CARD9 Deficiency on Neutrophil-Mediated Host Defense against Pulmonary Infection with Streptococcus pneumoniae., PMID:33020213

CARD9 prevents lung cancer development by suppressing the expansion of myeloid-derived suppressor cells and IDO production., PMID:31008530

Malassezia Is Associated with Crohn's Disease and Exacerbates Colitis in Mouse Models., PMID:30850233

First Case of Patient With Two Homozygous Mutations in MYD88 and CARD9 Genes Presenting With Pyogenic Bacterial Infections, Elevated IgE, and Persistent EBV Viremia., PMID:30837984

Glycosylation of HIV Env Impacts IgG Subtype Responses to Vaccination., PMID:30781796

Oral Administration of Human Polyvalent IgG by Mouthwash as an Adjunctive Treatment of Chronic Oral Candidiasis., PMID:30627128

The regenerating family member 3 β instigates IL-17A-mediated neutrophil recruitment downstream of NOD1/2 signalling for controlling colonisation resistance independently of microbiota community structure., PMID:30279238

Caspase recruitment domain-containing protein 9 (CARD9) knockout reduces regional ischemia/reperfusion injury through an attenuated inflammatory response., PMID:29940016

Spondyloarthritis, Acute Anterior Uveitis, and Fungi: Updating the Catterall-King Hypothesis., PMID:29675414

Ligation of Dectin-2 with a novel microbial ligand promotes adjuvant activity for vaccination., PMID:28793349

Card9 mediates susceptibility to intestinal pathogens through microbiota modulation and control of bacterial virulence., PMID:28790160

Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9., PMID:28130494

Moraxella catarrhalis induces CEACAM3-Syk-CARD9-dependent activation of human granulocytes., PMID:27038042

A novel PIK3CD C896T mutation detected in bilateral sudden sensorineural hearing loss using next generation sequencing: An indication of primary immunodeficiency., PMID:29937814

Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo., PMID:27032818

Successful Granulocyte Colony-stimulating Factor Treatment of Relapsing Candida albicans Meningoencephalitis Caused by CARD9 Deficiency., PMID:26658378

C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-κB activation., PMID:25202022

C-type lectin receptors differentially induce th17 cells and vaccine immunity to the endemic mycosis of North America., PMID:24391211

Primary immunodeficiencies underlying fungal infections., PMID:24240293

Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy and other primary immunodeficiency diseases help to resolve the nature of protective immunity against chronic mucocutaneous candidiasis., PMID:24240291

Card9 mediates intestinal epithelial cell restitution, T-helper 17 responses, and control of bacterial infection in mice., PMID:23732773

RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids., PMID:23064150

Antibody constant region peptides can display immunomodulatory activity through activation of the Dectin-1 signalling pathway., PMID:22952831

Unravelling fungal immunity through primary immune deficiencies., PMID:22818901

β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice., PMID:22328069

Protective role of naturally occurring interleukin-17A-producing γδ T cells in the lung at the early stage of systemic candidiasis in mice., PMID:21875963

Th17 cells, Job's syndrome and HIV: opportunities for bacterial and fungal infections., PMID:20543597

CARD9 versus CARMA1 in innate and adaptive immunity., PMID:19359218

Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation., PMID:19139169

Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells., PMID:19136564

Proinflammatory response of immature human dendritic cells is mediated by dectin-1 after exposure to Aspergillus fumigatus germ tubes., PMID:18279049

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17., PMID:17450144

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