Catalog No.
EHJ92705
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Val104-Gly427
Predicted molecular weight
38.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01854
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Immunoglobulin heavy constant epsilon, Ig epsilon chain C region, Ig epsilon chain C region ND, IGHE
Screening and Interaction Analysis of Shark-Derived Nanobodies against Crayfish Major Allergen Pro c 2., PMID:40256922
Fc-mediated immune stimulating, pro-inflammatory and antitumor effects of anti-HER2 IgE against HER2-expressing and trastuzumab-resistant tumors., PMID:40074330
CLEC7A Knockdown Alleviates Ischemic Stroke by Inhibiting Pyroptosis and Microglia Activation., PMID:39735961
Architecture of the high-affinity immunoglobulin E receptor., PMID:39656861
Differential cellular communication in tumor immune microenvironment during early and advanced stages of lung adenocarcinoma., PMID:39460829
The evolution of flexibility and function in the Fc domains of IgM, IgY, and IgE., PMID:39445016
Allosteric inhibition of IgE-FcεRI interactions by simultaneous targeting of IgE F(ab')2 epitopes., PMID:39179708
FCER1G as a novel immune-associated blood biomarker in cardiogenic stroke., PMID:39071704
Modulation of the high concentration viscosity of IgG1 antibodies using clinically validated Fc mutations., PMID:39028186
Generation of a virus-like particles based vaccine against IgE., PMID:38445568
Dysfunctional network of hub genes in hypertrophic cardiomyopathy patients., PMID:36628247
An Analysis of Biologic Therapies in Patients With Asthma and Chronic Rhinosinusitis., PMID:36225247
Combined IgE neutralization and Bifidobacterium longum supplementation reduces the allergic response in models of food allergy., PMID:36167830
Fc Fragment of IgE Receptor Ig (FCER1G) acts as a key gene involved in cancer immune infiltration and tumour microenvironment., PMID:36054819
Integrated Bioinformatics-Based Analysis of Hub Genes and the Mechanism of Immune Infiltration Associated With Acute Myocardial Infarction., PMID:35463752
The eIg technology to generate Ig-like bispecific antibodies., PMID:35427197
DNTTIP1 is a Prognostic Biomarker Correlated With Immune Infiltrates in Hepatocellular Carcinoma: A Study Based on The Cancer Genome Atlas Data., PMID:35265097
Abatacept (Cytotoxic T Lymphocyte Antigen 4-Fragment Crystallizable) Reduces Allergic Inflammation of Ovalbumin-Sensitized Mice., PMID:34994213
Development of a novel reporter gene assay to evaluate antibody-dependent cellular phagocytosis for anti-CD20 therapeutic antibodies., PMID:34521023
FCER1G and PTGS2 Serve as Potential Diagnostic Biomarkers of Acute Myocardial Infarction Based on Integrated Bioinformatics Analyses., PMID:34115526
Haemonchus contortus infection induces a variable immune response in resistant and susceptible Pelibuey sheep., PMID:33667946
An Omalizumab Biobetter Antibody With Improved Stability and Efficacy for the Treatment of Allergic Diseases., PMID:33329588
Targeting FcRn for immunomodulation: Benefits, risks, and practical considerations., PMID:32896308
Bioinformatics analysis reveals novel hub gene pathways associated with IgA nephropathy., PMID:32894197
The Role of IgG4 in the Fine Tuning of Tolerance in IgE-Mediated Allergy and Cancer., PMID:32708690
Precision medicine in clinical oncology: the journey from IgG antibody to IgE., PMID:32349107
Engineering the Fab fragment of the anti-IgE omalizumab to prevent Fab crystallization and permit IgE-Fc complex crystallization., PMID:32133997
Structure of intact IgE and the mechanism of ligelizumab revealed by electron microscopy., PMID:32037590
Enhanced expression of FCER1G predicts positive prognosis in multiple myeloma., PMID:31956364
Imaging the Substructures of Individual IgE Antibodies with Atomic Force Microscopy., PMID:31661619
Human DC-SIGN and CD23 do not interact with human IgG., PMID:31292524
Immunoglobulin G structure and rheumatoid factor epitopes., PMID:31199818
Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch., PMID:31027996
Biologics for chronic inflammatory skin diseases: an update for the clinician., PMID:30827126
GSK2646264, a spleen tyrosine kinase inhibitor, attenuates the release of histamine in ex vivo human skin., PMID:30735243
Intravenous immunoglobulin induces IL-4 in human basophils by signaling through surface-bound IgE., PMID:30529242
TFPI-2 Protects Against Gram-Negative Bacterial Infection., PMID:30254643
Human colorectal cancer antigen GA733-2-Fc fused to endoplasmic reticulum retention motif KDEL enhances its immunotherapeutic effects., PMID:30249898
EFab domain substitution as a solution to the light-chain pairing problem of bispecific antibodies., PMID:30215570
Synthetic DNA delivery by electroporation promotes robust in vivo sulfation of broadly neutralizing anti-HIV immunoadhesin eCD4-Ig., PMID:30174283
Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody., PMID:30069035
Omalizumab in the Therapy of Pediatric Asthma., PMID:29714140
Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction., PMID:29295972
Effects of genetic factors to inhaled corticosteroid response in children with asthma: a literature review., PMID:29251255
Maternal IgG immune complexes induce food allergen-specific tolerance in offspring., PMID:29158374
Thermal sensitivity and flexibility of the Cε3 domains in immunoglobulin E., PMID:28844738
Anti-FcγRIIB mAb suppresses murine IgG-dependent anaphylaxis by Fc domain targeting of FcγRIII., PMID:28624610
Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab., PMID:28438838
IgE binds asymmetrically to its B cell receptor CD23., PMID:28361904
For research use only. Not for human or drug use.
