Catalog No.
RHF98601
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Centromere protein C, CENP-C, Centromere autoantigen C, Centromere protein C 1, CENP-C 1, Interphase centromere complex protein 7, CENPC, CENPC1, ICEN7
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q03188
Applications
IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA2160
Anti-CENP-C Antibody-Based Immunofluorescence Dicentric Assay: Radiation Dose-Response, Validation Studies, and Radiation Dose-Dependency on Sister Centromere Fluorescence., PMID:36442049
Immunization with CENP-C Causes Aberrant Chromosome Segregation during Oocyte Meiosis in Mice., PMID:33604391
Unequal contribution of two paralogous CENH3 variants in cowpea centromere function., PMID:33319863
A fraction of barrier-to-autointegration factor (BAF) associates with centromeres and controls mitosis progression., PMID:32814801
Antigen-driven selection of antibodies against SSA, SSB and the centromere 'complex', including a novel antigen, MIS12 complex, in human salivary glands., PMID:31611218
MutS-Homolog2 silencing generates tetraploid meiocytes in tomato (Solanum lycopersicum)., PMID:31245679
Defining the epichromatin epitope., PMID:28960120
Stepwise unfolding supports a subunit model for vertebrate kinetochores., PMID:28265097
Targeting of Arabidopsis KNL2 to Centromeres Depends on the Conserved CENPC-k Motif in Its C Terminus., PMID:28062749
Anticentromere antibody-positive primary Sjögren's syndrome: Epitope analysis of a subset of anticentromere antibody-positive patients., PMID:27161330
Active centromere and chromosome identification in fixed cell lines., PMID:27011768
A quantitative description of Ndc80 complex linkage to human kinetochores., PMID:26345214
Distinct organization and regulation of the outer kinetochore KMN network downstream of CENP-C and CENP-T., PMID:25660545
Diversity of humoral responses to the centromere proteins among HCV-related chronic liver disease, PBC and AIH patients., PMID:25220385
Alisertib added to rituximab and vincristine is synthetic lethal and potentially curative in mice with aggressive DLBCL co-overexpressing MYC and BCL2., PMID:24893165
De novo centromere formation on a chromosome fragment in maize., PMID:23530217
CENP-C recruits M18BP1 to centromeres to promote CENP-A chromatin assembly., PMID:21911481
Anti-CENPI autoantibodies in scleroderma patients with features of autoimmune liver diseases., PMID:21888900
A population-based investigation of the autoantibody profile in mothers of children with atrioventricular block., PMID:21815910
Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochore., PMID:21353556
CENP-C is a structural platform for kinetochore assembly., PMID:21353555
CaMtw1, a member of the evolutionarily conserved Mis12 kinetochore protein family, is required for efficient inner kinetochore assembly in the pathogenic yeast Candida albicans., PMID:21276093
Interstitial deletion of proximal 8q including part of the centromere from unbalanced segregation of a paternal deletion/marker karyotype with neocentromere formation at 8p22., PMID:21212645
Centromere protein A dynamics in human pluripotent stem cell self-renewal, differentiation and DNA damage., PMID:20650959
A monoclonal antibody toolkit for C. elegans., PMID:20405020
Evolutionary descent of a human chromosome 6 neocentromere: a jump back to 17 million years ago., PMID:19411601
Characterization of a neocentric supernumerary marker chromosome originating from the Xp distal region by FISH, CENP-C staining, and array CGH., PMID:17268194
Molecular cytogenetic identification and characterization of a de novo supernumerary neocentromeric derivative chromosome 13., PMID:16954674
Partitioning of the maize epigenome by the number of methyl groups on histone H3 lysines 9 and 27., PMID:16624902
Distinct recognition of antibodies to centromere proteins in primary Sjogren's syndrome compared with limited scleroderma., PMID:16414973
Stable barley chromosomes without centromeric repeats., PMID:15998740
Characterization of a CENP-C homolog in Arabidopsis thaliana., PMID:15329494
Centromeric DNA sequences in the pathogenic yeast Candida albicans are all different and unique., PMID:15272074
Characterization of an analphoid, neocentromere-positive inv dup 8p marker chromosome using multiplex whole chromosome and sub-telomere FISH analyses., PMID:15183754
Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing., PMID:15182667
Differential localization of the centromere-specific proteins in the major centromeric satellite of Arabidopsis thaliana., PMID:15161939
Human centromere repositioning "in progress"., PMID:15084747
Human artificial chromosomes containing chromosome 17 alphoid DNA maintain an active centromere in murine cells but are not stable., PMID:15081114
Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase., PMID:15009096
CENP-B interacts with CENP-C domains containing Mif2 regions responsible for centromere localization., PMID:14612452
Effects of anti-leukemia drug Harringtonine on the levels of centromere proteins and gene expression of CenpB in L1210 cells., PMID:12939796
Genomic microarray analysis reveals distinct locations for the CENP-A binding domains in three human chromosome 13q32 neocentromeres., PMID:12928482
Partially functional Cenpa-GFP fusion protein causes increased chromosome missegregation and apoptosis during mouse embryogenesis., PMID:12906131
Proteomic analysis of human metaphase chromosomes reveals topoisomerase II alpha as an Aurora B substrate., PMID:12466558
Identification of a neocentromere in a rearranged Y chromosome with no detectable DYZ3 centromeric sequence., PMID:12439894
Extensive cytogenetic analysis of a stable dicentric isochromosome 21, idic(21), formed by fusion of the terminal long arms., PMID:12438703
Recognition of Granzyme B-generated autoantigen fragments in scleroderma patients with ischemic digital loss., PMID:12124872
Chromosome 13q neocentromeres: molecular cytogenetic characterization of three additional cases and clinical spectrum., PMID:12116235
CENP-A, -B, and -C chromatin complex that contains the I-type alpha-satellite array constitutes the prekinetochore in HeLa cells., PMID:11884609
Cytogenetic analysis and construction of a BAC contig across a common neocentromeric region from 9p., PMID:11534819
For research use only. Not for human or drug use.
