Catalog No.
PHJ53301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human WWTR1 (Met1-Leu400).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Transcriptional coactivator with PDZ-binding motif,TAZ,WW domain-containing transcription regulator protein 1,WWTR1
Purification
Purified by antigen affinity column.
Accession
Q9GZV5
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
YAP/TAZ are crucial regulators of macrophage-mediated pulmonary inflammation and fibrosis after bleomycin-induced injury., PMID:39915054
Transition to a mesenchymal state in neuroblastoma may be characterized by a high expression of GD2 and by the acquisition of immune escape from NK cells., PMID:38736882
Epigenome-wide DNA methylation analysis of myasthenia gravis., PMID:37254650
An Anti-TAZ Monoclonal Antibody Recognizing Cell Surface Expressed TAZ Protein in Human Tumor Cells., PMID:36789121
Neuroblastoma Tumor-Associated Mesenchymal Stromal Cells Regulate the Cytolytic Functions of NK Cells., PMID:36612020
Prostate tumor-induced stromal reprogramming generates Tenascin C that promotes prostate cancer metastasis through YAP/TAZ inhibition., PMID:34845375
Loss of Yap/Taz in cardiac fibroblasts attenuates adverse remodelling and improves cardiac function., PMID:34132780
Oxygen regulates epithelial stem cell proliferation via RhoA-actomyosin-YAP/TAZ signal in mouse incisor., PMID:33472844
New insights into the pathophysiology and clinical care of rare primary liver cancers., PMID:33205035
Fluorescence in situ hybridization for WWTR1-CAMTA1 has higher sensitivity and specificity for epithelioid hemangioendothelioma diagnosis., PMID:32913529
Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis., PMID:32259482
CAMTA-1 Expression in 24 Cases of Hepatic Epithelioid Hemangioendothelioma in a Single Institute: Diagnostic Utility for Differential Diagnosis from Hepatic Angiosarcoma., PMID:31662570
Immunofluorescence Microscopy to Study Endogenous TAZ in Mammalian Cells., PMID:30565129
Low-Intensity Pulsed Ultrasound Treatment Accelerates Angiogenesis by Activating YAP/TAZ in Human Umbilical Vein Endothelial Cells., PMID:30205992
Acacetin regulated the reciprocal differentiation of Th17 cells and Treg cells and mitigated the symptoms of collagen-induced arthritis in mice., PMID:30176062
Fibulin-5 promotes airway smooth muscle cell proliferation and migration via modulating Hippo-YAP/TAZ pathway., PMID:28942149
Immunohistochemistry for NF2, LATS1/2, and YAP/TAZ Fails to Separate Benign From Malignant Mesothelial Proliferations., PMID:27128293
The 2015 World Health Organization Classification of Tumors of the Pleura: Advances since the 2004 Classification., PMID:26811225
Nuclear Expression of CAMTA1 Distinguishes Epithelioid Hemangioendothelioma From Histologic Mimics., PMID:26414223
A role for the transducer of the Hippo pathway, TAZ, in the development of aggressive types of endometrial cancer., PMID:26381823
RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells., PMID:26320173
Yap and Taz are required for Ret-dependent urinary tract morphogenesis., PMID:26243870
Mechanism of action of a WWTR1(TAZ)-CAMTA1 fusion oncoprotein., PMID:25961935
Actin remodelling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking., PMID:25849865
CAMTA1 immunostaining is not useful in differentiating epithelioid hemangioendothelioma from its potential mimickers., PMID:25110239
Substratum stiffness and latrunculin B modulate the gene expression of the mechanotransducers YAP and TAZ in human trabecular meshwork cells., PMID:23727052
The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ., PMID:23026745
Bone metastatic process of breast cancer involves methylation state affecting E-cadherin expression through TAZ and WWOX nuclear effectors., PMID:22717556
A cell-permeable fusion protein for the mineralization of human dental pulp stem cells., PMID:21990606
For research use only. Not for human or drug use.
