Catalog No.
RHC41702
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Protein Wnt-2, Int-1-like protein 1, Int-1-related protein, IRP, WNT2, INT1L1, IRP
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P09544
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA2156
WNT2-SOX4 positive feedback loop promotes chemoresistance and tumorigenesis by inducing stem-cell like properties in gastric cancer., PMID:37634009
Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b., PMID:36220068
A novel strategy to identify candidate diagnostic and prognostic biomarkers for gastric cancer., PMID:34215253
Targeting cancer-associated fibroblast-secreted WNT2 restores dendritic cell-mediated antitumour immunity., PMID:33692094
WT1 influences apoptosis and proliferation of immature mice granular cells through regulation of the wnt/β-catenin signal pathway., PMID:31880532
Relevance of VEGFA in rat livers subjected to partial hepatectomy under ischemia-reperfusion., PMID:31254006
Targeting Endothelial Erk1/2-Akt Axis as a Regeneration Strategy to Bypass Fibrosis during Chronic Liver Injury in Mice., PMID:30266653
Metformin regulates stromal-epithelial cells communication via Wnt2/β-catenin signaling in endometriosis., PMID:26116230
Clinicopathological significance of wnt/β-catenin signaling pathway in esophageal squamous cell carcinoma., PMID:26045816
Wnt2 protein plays a role in the progression of pancreatic cancer promoted by pancreatic stellate cells., PMID:25731618
Wingless-type MMTV integration site family member 2 (WNT2) gene is associated with resistance to MAP in faecal culture and antibody response in Holstein cattle., PMID:25643727
Gene expression profiles of various cytokines in mesenchymal stem cells derived from umbilical cord tissue and bone marrow following infection with human cytomegalovirus., PMID:24569981
Inhibition of Wnt signaling induces cell apoptosis and suppresses cell proliferation in cholangiocarcinoma cells., PMID:23799613
Hepatitis C virus core protein activates Wnt/β-catenin signaling through multiple regulation of upstream molecules in the SMMC-7721 cell line., PMID:21340743
Mesenchymal stem cells produce Wnt isoforms and TGF-beta1 that mediate proliferation and procollagen expression by lung fibroblasts., PMID:19734317
Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells., PMID:19038973
Stromal transforming growth factor-beta signaling mediates prostatic response to androgen ablation by paracrine Wnt activity., PMID:18559517
Expression of seven gastric cancer-associated genes and its relevance for Wnt, NF-kappaB and Stat3 signaling., PMID:18184402
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway., PMID:17948129
Expression of Wnt pathway components frizzled and disheveled in colon cancer arising in patients with inflammatory bowel disease., PMID:17671721
WNT signaling pathway and stem cell signaling network., PMID:17634527
WNT2B: comparative integromics and clinical applications (Review)., PMID:16273293
Epithelial-mesenchymal transition in gastric cancer (Review)., PMID:16273224
Wnt2 as a new therapeutic target in malignant pleural mesothelioma., PMID:15900580
The proinvasive activity of Wnt-2 is mediated through a noncanonical Wnt pathway coupled to GSK-3beta and c-Jun/AP-1 signaling., PMID:15507471
An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth., PMID:15289346
Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells., PMID:15208662
Sonic hedgehog signaling regulates Gli3 processing, mesenchymal proliferation, and differentiation during mouse lung organogenesis., PMID:15136151
WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer., PMID:14517837
Wnt ligand expression in malignant melanoma: pilot study indicating correlation with histopathological features., PMID:14514922
Expression of Wnt ligands and Frizzled receptors in colonic mucosa and in colon carcinoma., PMID:12147710
Induced repatterning of type XVIII collagen expression in ureter bud from kidney to lung type: association with sonic hedgehog and ectopic surfactant protein C., PMID:11290296
For research use only. Not for human or drug use.
