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Anti-Human PMEL17/ME20M Antibody (17A9)

Catalog #:   RHE28701 Specific References (97) DATASHEET
Host species: Human
Isotype: IgG1, kappa
Applications: ELISA, FCM, IHC
Accession: P40967
Overview

Catalog No.

RHE28701

Species reactivity

Human

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

Melanocyte protein PMEL, ME20-M, ME20M, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, P1, P100, Premelanosome protein, Silver locus protein homolog, M-alpha, 95 kDa melanocyte-specific secreted glycoprotein, P26, Secreted melanoma-associated ME20 antigen, ME20-S, ME20S, M-beta, PMEL, D12S53E, PMEL17, SILV

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P40967

Applications

ELISA, FCM, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

17A9

Data Image
References

[Clinicopathological features of metastatic melanoma in effusion cytology of serosal cavity]., PMID:39103266

[Clinicopathological features of metastatic melanoma in effusion cytology of serosal cavity]., PMID:39103266

PRAME and Historical Immunohistochemical Antibodies Ki-67, P16, and HMB-45 in Ambiguous Melanocytic Tumors., PMID:38916203

PRAME and Historical Immunohistochemical Antibodies Ki-67, P16, and HMB-45 in Ambiguous Melanocytic Tumors., PMID:38916203

Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD., PMID:35473441

Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD., PMID:35473441

Primary leptomeningeal melanomatosis successfully treated with PD-1 inhibitor pembrolizumab: A case report., PMID:33327228

Primary leptomeningeal melanomatosis successfully treated with PD-1 inhibitor pembrolizumab: A case report., PMID:33327228

Indication of Premelanosome Protein (PMEL) Expression Outside of Pigmented Bovine Skin Suggests Functions Beyond Eumelanogenesis., PMID:32668786

Indication of Premelanosome Protein (PMEL) Expression Outside of Pigmented Bovine Skin Suggests Functions Beyond Eumelanogenesis., PMID:32668786

CD10 and p63 expression in a sarcomatoid undifferentiated melanoma: A cautionary (and molecularly annotated) tale., PMID:31943331

CD10 and p63 expression in a sarcomatoid undifferentiated melanoma: A cautionary (and molecularly annotated) tale., PMID:31943331

PNL2: A Useful Adjunct Biomarker to HMB45 in the Diagnosis of Uterine Perivascular Epithelioid Cell Tumor (PEComa)., PMID:31851063

PNL2: A Useful Adjunct Biomarker to HMB45 in the Diagnosis of Uterine Perivascular Epithelioid Cell Tumor (PEComa)., PMID:31851063

Utility of p16-Ki-67-HMB45 score in sorting benign from malignant Spitz tumors., PMID:31351802

ABCB6 Resides in Melanosomes and Regulates Early Steps of Melanogenesis Required for PMEL Amyloid Matrix Formation., PMID:29940187

Radiologic and Histopathologic Correlation of Different Growth Patterns of Metastatic Uveal Melanoma to the Liver., PMID:29122287

ABCB6 Resides in Melanosomes and Regulates Early Steps of Melanogenesis Required for PMEL Amyloid Matrix Formation., PMID:29940187

Hepatic perivascular epithelioid cell tumor (PEComa): a case report with a review of literatures., PMID:28288506

Hepatic perivascular epithelioid cell tumor (PEComa): a case report with a review of literatures., PMID:28288506

Increased Activity and Number of Epidermal Melanocytes in Lesional Psoriatic Skin., PMID:27497917

Hashimoto's thyroiditis could be secondary to vitiligo: the possibility of antigen crossover and oxidative stress between the two diseases., PMID:27020052

Hashimoto's thyroiditis could be secondary to vitiligo: the possibility of antigen crossover and oxidative stress between the two diseases., PMID:27020052

Metastatic melanoma of the tongue: a case report with immunohistochemical profile., PMID:25427453

Metastatic melanoma of the tongue: a case report with immunohistochemical profile., PMID:25427453

Antibody αPEP13h reacts with lymphangioleiomyomatosis cells in lung nodules., PMID:25411763

Antibody αPEP13h reacts with lymphangioleiomyomatosis cells in lung nodules., PMID:25411763

Hyperosmotic stress reduces melanin production by altering melanosome formation., PMID:25170965

Hyperosmotic stress reduces melanin production by altering melanosome formation., PMID:25170965

A monoclonal antibody against PMEL., PMID:25118787

A monoclonal antibody against PMEL., PMID:25118787

Marginal and joint distributions of S100, HMB-45, and Melan-A across a large series of cutaneous melanomas., PMID:23899062

Marginal and joint distributions of S100, HMB-45, and Melan-A across a large series of cutaneous melanomas., PMID:23899062

Value of melanocytic-associated immunohistochemical markers in the diagnosis of malignant melanoma: a review and update., PMID:23648379

Value of melanocytic-associated immunohistochemical markers in the diagnosis of malignant melanoma: a review and update., PMID:23648379

[Detection of serum autoantibodies against premelanosome protein 17 increases in the vitiligo patients]., PMID:23643172

[Detection of serum autoantibodies against premelanosome protein 17 increases in the vitiligo patients]., PMID:23643172

Metastatic melanoma presenting as an isolated breast tumor: a study of 20 cases with emphasis on several primary mimickers., PMID:23276173

Metastatic melanoma presenting as an isolated breast tumor: a study of 20 cases with emphasis on several primary mimickers., PMID:23276173

The melanosomal protein PMEL17 as a target for antibody drug conjugate therapy in melanoma., PMID:22613716

The melanosomal protein PMEL17 as a target for antibody drug conjugate therapy in melanoma., PMID:22613716

Perivascular epithelioid cell tumor (PEComa) of gynecologic origin: a clinicopathological study of three cases., PMID:22439417

Perivascular epithelioid cell tumor (PEComa) of gynecologic origin: a clinicopathological study of three cases., PMID:22439417

A mouse model of vitiligo with focused epidermal depigmentation requires IFN-γ for autoreactive CD8⁺ T-cell accumulation in the skin., PMID:22297636

A mouse model of vitiligo with focused epidermal depigmentation requires IFN-γ for autoreactive CD8⁺ T-cell accumulation in the skin., PMID:22297636

Aberrant expression of HMB-45 in traumatized melanocytic nevi., PMID:22285619

Aberrant expression of HMB-45 in traumatized melanocytic nevi., PMID:22285619

Epithelioid angiosarcoma of bone and soft tissue: a report of seven cases with emphasis on morphologic diversity, immunohistochemical features and clinical outcome., PMID:22158488

Epithelioid angiosarcoma of bone and soft tissue: a report of seven cases with emphasis on morphologic diversity, immunohistochemical features and clinical outcome., PMID:22158488

Primary oral melanoma: a histopathological and immunohistochemical study of 22 cases of Latin America., PMID:22143732

Primary oral melanoma: a histopathological and immunohistochemical study of 22 cases of Latin America., PMID:22143732

The use of immunocytochemical study in the cytologic diagnosis of melanoma: evaluation of three antibodies., PMID:22021247

The use of immunocytochemical study in the cytologic diagnosis of melanoma: evaluation of three antibodies., PMID:22021247

Melanoma-associated antigen expression in lymphangioleiomyomatosis renders tumor cells susceptible to cytotoxic T cells., PMID:19893037

Melanoma-associated antigen expression in lymphangioleiomyomatosis renders tumor cells susceptible to cytotoxic T cells., PMID:19893037

The secreted form of a melanocyte membrane-bound glycoprotein (Pmel17/gp100) is released by ectodomain shedding., PMID:19884326

The secreted form of a melanocyte membrane-bound glycoprotein (Pmel17/gp100) is released by ectodomain shedding., PMID:19884326

Impact of a recombinant fowlpox vaccine on the efficacy of adoptive cell therapy with tumor infiltrating lymphocytes in a patient with metastatic melanoma., PMID:19752747

Impact of a recombinant fowlpox vaccine on the efficacy of adoptive cell therapy with tumor infiltrating lymphocytes in a patient with metastatic melanoma., PMID:19752747

No correlation between clinical response to CTLA-4 blockade and presence of NY-ESO-1 antibody in patients with metastatic melanoma., PMID:19752745

No correlation between clinical response to CTLA-4 blockade and presence of NY-ESO-1 antibody in patients with metastatic melanoma., PMID:19752745

Expression hierarchy of T cell epitopes from melanoma differentiation antigens: unexpected high level presentation of tyrosinase-HLA-A2 Complexes revealed by peptide-specific, MHC-restricted, TCR-like antibodies., PMID:19414786

Expression hierarchy of T cell epitopes from melanoma differentiation antigens: unexpected high level presentation of tyrosinase-HLA-A2 Complexes revealed by peptide-specific, MHC-restricted, TCR-like antibodies., PMID:19414786

Gpnmb is a melanosome-associated glycoprotein that contributes to melanocyte/keratinocyte adhesion in a RGD-dependent fashion., PMID:19320736

Gpnmb is a melanosome-associated glycoprotein that contributes to melanocyte/keratinocyte adhesion in a RGD-dependent fashion., PMID:19320736

Granular cell tumor of the oral cavity: updated immunohistochemical profile., PMID:19192059

Granular cell tumor of the oral cavity: updated immunohistochemical profile., PMID:19192059

Improved tumor immunity using anti-tyrosinase related protein-1 monoclonal antibody combined with DNA vaccines in murine melanoma., PMID:19047169

Improved tumor immunity using anti-tyrosinase related protein-1 monoclonal antibody combined with DNA vaccines in murine melanoma., PMID:19047169

Novel approach to the characterization of melanoma associated-peptide-specific CTL lines from Japanese metastatic melanoma patients., PMID:18695871

Novel approach to the characterization of melanoma associated-peptide-specific CTL lines from Japanese metastatic melanoma patients., PMID:18695871

Nuclear to non-nuclear Pmel17/gp100 expression (HMB45 staining) as a discriminator between benign and malignant melanocytic lesions., PMID:18552823

Nuclear to non-nuclear Pmel17/gp100 expression (HMB45 staining) as a discriminator between benign and malignant melanocytic lesions., PMID:18552823

The silver locus product (Silv/gp100/Pmel17) as a new tool for the analysis of melanosome transfer in human melanocyte-keratinocyte co-culture., PMID:18331332

The silver locus product (Silv/gp100/Pmel17) as a new tool for the analysis of melanosome transfer in human melanocyte-keratinocyte co-culture., PMID:18331332

Premelanosome amyloid-like fibrils are composed of only golgi-processed forms of Pmel17 that have been proteolytically processed in endosomes., PMID:17991747

Premelanosome amyloid-like fibrils are composed of only golgi-processed forms of Pmel17 that have been proteolytically processed in endosomes., PMID:17991747

Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs., PMID:17898045

Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs., PMID:17898045

Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2'-deoxycytidine in cutaneous melanoma: immunotherapeutic implications., PMID:17545540

Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2'-deoxycytidine in cutaneous melanoma: immunotherapeutic implications., PMID:17545540

Biomarker discovery from uveal melanoma secretomes: identification of gp100 and cathepsin D in patient serum., PMID:17539671

Biomarker discovery from uveal melanoma secretomes: identification of gp100 and cathepsin D in patient serum., PMID:17539671

Immunological activation following transcutaneous delivery of HR-gp100 protein., PMID:17493711

Immunological activation following transcutaneous delivery of HR-gp100 protein., PMID:17493711

Melanocortin 1 receptor is expressed by uveal malignant melanoma and can be considered a new target for diagnosis and immunotherapy., PMID:17325166

Melanocortin 1 receptor is expressed by uveal malignant melanoma and can be considered a new target for diagnosis and immunotherapy., PMID:17325166

Sialylated core 1 O-glycans influence the sorting of Pmel17/gp100 and determine its capacity to form fibrils., PMID:17303571

Sialylated core 1 O-glycans influence the sorting of Pmel17/gp100 and determine its capacity to form fibrils., PMID:17303571

Presentation of tumor antigens by dendritic cells genetically modified with viral and nonviral vectors., PMID:17063124

Presentation of tumor antigens by dendritic cells genetically modified with viral and nonviral vectors., PMID:17063124

Analysis of antitumor activity elicited by vaccination with combinations of interleukin-12 DNA with gp100 DNA or the chemokine CCL21 in vivo., PMID:16942445

Analysis of antitumor activity elicited by vaccination with combinations of interleukin-12 DNA with gp100 DNA or the chemokine CCL21 in vivo., PMID:16942445

Desmoplastic melanoma: comparison of expression of differentiation antigens and cancer testis antigens., PMID:16845331

Desmoplastic melanoma: comparison of expression of differentiation antigens and cancer testis antigens., PMID:16845331

The repeat domain of the melanosomal matrix protein PMEL17/GP100 is required for the formation of organellar fibers., PMID:16682408

The repeat domain of the melanosomal matrix protein PMEL17/GP100 is required for the formation of organellar fibers., PMID:16682408

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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Anti-Human PMEL17/ME20M Antibody (17A9) [RHE28701]
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