Catalog No.
DHJ30701
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG1
Clonality
Monoclonal
Target
Interleukin-1 family member 10, IL-1F10, Family of interleukin 1-theta, FIL1 theta, Interleukin-1 HY2, IL-1HY2, Interleukin-1 theta, IL-1 theta, Interleukin-38, IL-38, IL1F10, FIL1T, IL1HY2, IL38, FKSG75, UNQ6119/PRO20041
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q8WWZ1
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
IMM-ONC-01
IL-38 as a Novel Biomarker in Multiple Myeloma Patients: A Prospective Clinical Evaluation., PMID:40370815
Interleukin-38-overexpressing adenovirus infection in dendritic cell-based treatment enhances immunotherapy for allergic asthma via inducing Foxp3+ regulatory T cells., PMID:39667222
Interleukin 38 reduces antigen-presentation capacity and antibody production after vaccination., PMID:39353267
Autoantibody mediated deficiency of IL-36-receptor antagonist in a subset of patients with psoriasis and psoriatic arthritis., PMID:39265919
Neutralizing IL-38 activates γδ T cell-dependent antitumor immunity and sensitizes for chemotherapy., PMID:39209451
Serum PYCARD may become a new diagnostic marker for rheumatoid arthritis patients., PMID:38576041
IL-38 blockade induces anti-tumor immunity by abrogating tumor-mediated suppression of early immune activation., PMID:37216961
Cell Intrinsic IL-38 Affects B Cell Differentiation and Antibody Production., PMID:36982750
Interleukin-36 cytokines are overexpressed in the skin and sera of patients with bullous pemphigoid., PMID:36940975
Assessment of the levels of interleukin-17 and interleukin-38 in thyroid-associated ophthalmopathy patients., PMID:36894821
Regulatory effect of IL-38 on NF-κB pathway in systemic lupus erythematosus., PMID:36621308
IL-38, a potential therapeutic agent for lupus, inhibits lupus progression., PMID:35776155
Contribution of IL-38 in Lung Immunity during Pseudomonas Aeruginosa-induced Pneumonia., PMID:35583912
Study effect of probiotics and prebiotics on treatment of OVA-LPS-induced of allergic asthma inflammation and pneumonia by regulating the TLR4/NF-kB signaling pathway., PMID:35296330
Evaluation of Serum Interleukin-38 Levels in Different Radiographic Grades of Idiopathic Knee Osteoarthritis., PMID:34788133
Neutralization of interleukin-38 exacerbates coxsackievirus B3-induced acute myocarditis in mice., PMID:34775963
Interleukin-1 Blockade in Polygenic Autoinflammatory Disorders: Where Are We now?, PMID:33708123
Blockade of Th17 response by IL-38 in primary Sjögren's syndrome., PMID:32950755
Future perspective: biologic agents in patients with severe COVID-19., PMID:32883116
Interleukin-38 protects against sepsis by augmenting immunosuppressive activity of CD4+ CD25+ regulatory T cells., PMID:31880383
IL-38 is a biomarker for acute respiratory distress syndrome in humans and down-regulates Th17 differentiation in vivo., PMID:31756565
IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from γδ T Cells., PMID:30995480
[Correlation between serum interleukin-38 and acute exacerbation of chronic obstructive pulmonary disease with pulmonary embolism]., PMID:30917443
[IL-1 family cytokines in chronic inflammatory disorders]., PMID:30909697
IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment., PMID:30377293
Interleukin 30 to Interleukin 40., PMID:30328794
Interleukin 38 Protects Against Lethal Sepsis., PMID:29762676
[Interleukin-38 expression and clinical significance in serum of patients with chronic obstructive pulmonary disease]., PMID:29562401
Overexpression of IL-38 protein in anticancer drug-induced lung injury and acute exacerbation of idiopathic pulmonary fibrosis., PMID:28942884
Cytokines of the IL-1 family: recognized targets in chronic inflammation underrated in organ transplantations., PMID:28798075
In vivo anti-inflammatory activities of novel cytokine IL-38 in Murphy Roths Large (MRL)/lpr mice., PMID:27769564
Aberrant Expression of Novel Cytokine IL-38 and Regulatory T Lymphocytes in Childhood Asthma., PMID:27438823
Detection of the novel IL-1 family cytokines by QAH-IL1F-1 assay in rheumatoid arthritis., PMID:27188731
IL-38: A new factor in rheumatoid arthritis., PMID:29124228
Expression, purification of IL-38 in Escherichia coli and production of polyclonal antibodies., PMID:25448591
For research use only. Not for human or drug use.
