Catalog No.
RHJ18901
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Target
Extracellular sulfatase Sulf-2, hSulf-2, Arylsulfatase, 3.1.6.1, N-acetylglucosamine-6-sulfatase, 3.1.6.14, Extracellular sulfatase Sulf-2 secreted form, SULF2, KIAA1247, UNQ559/PRO1120
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q8IWU5
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
8G1
Galectin-3-Binding Protein Inhibits Extracellular Heparan 6-O-Endosulfatase Sulf-2., PMID:38825040
Galectin-3-binding protein inhibits extracellular heparan 6-O-endosulfatse Sulf-2., PMID:38187586
Regulation of fractone heparan sulfate composition in young and aged subventricular zone neurogenic niches., PMID:34324645
Sulfatase 2 (SULF2) Monoclonal Antibody 5D5 Suppresses Human Cholangiocarcinoma Xenograft Growth Through Regulation of a SULF2-Platelet-Derived Growth Factor Receptor Beta-Yes-Associated Protein Signaling Axis., PMID:33735525
Expression of the Extracellular Sulfatase SULF2 Affects Survival of Head and Neck Squamous Cell Carcinoma Patients., PMID:33585200
Detection of selection signatures for response to Aleutian mink disease virus infection in American mink., PMID:33536540
Association between herpes simplex virus 1 exposure and the risk of depression in UK Biobank., PMID:32564518
Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling., PMID:27294358
SULF1/SULF2 reactivation during liver damage and tumour growth., PMID:27013228
SULF2 Expression Is a Potential Diagnostic and Prognostic Marker in Lung Cancer., PMID:26882224
Evaluation of antiglypican-3 therapy as a promising target for amelioration of hepatic tissue damage in hepatocellular carcinoma., PMID:25449037
Sulf1 and Sulf2 expression in the nervous system and its role in limiting neurite outgrowth in vitro., PMID:25448158
SULF2, a heparan sulfate endosulfatase, is present in the blood of healthy individuals and increases in cirrhosis., PMID:25444749
Role of 6-O-sulfated heparan sulfate in chronic renal fibrosis., PMID:24878958
SULF2 expression by immunohistochemistry and overall survival in oesophageal cancer: a cohort study., PMID:23180455
Differential sulfation remodelling of heparan sulfate by extracellular 6-O-sulfatases regulates fibroblast growth factor-induced boundary formation by glial cells: implications for glial cell transplantation., PMID:23136428
Heparan sulfate subdomains that are degraded by Sulf accumulate in cerebral amyloid ß plaques of Alzheimer's disease: evidence from mouse models and patients., PMID:22429964
The role of glypican-3 in regulating Wnt in hepatocellular carcinomas., PMID:22563565
Use of a phage display antibody to measure the enzymatic activity of the Sulfs., PMID:20816204
Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88., PMID:19822709
Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity., PMID:16901266
For research use only. Not for human or drug use.
