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Recombinant Dog CD154/CD40LG/TNFSF5 Protein, C-Fc

Catalog #:   EQD85401 Specific References (27) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: Mammalian Cells
Accession: O97626
Protein length: Gln113-Leu260
Overview

Catalog No.

EQD85401

Expression system

Mammalian Cells

Species

Canis lupus familiaris (Dog) (Canis familiaris)

Protein length

Gln113-Leu260

Predicted molecular weight

44.04 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

O97626

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

CD40 ligand, CD40-L, Tumor necrosis factor ligand superfamily member 5, CD154, CD40 ligand, membrane form, CD40 ligand, soluble form, sCD40L, CD40LG, CD40L, TNFSF5

Data Image
References

Impact of artificial waterholes on temporal partitioning in a carnivore guild: a comparison of activity patterns at artificial waterholes to roads and trails., PMID:37159833

Single-cell characterization of dog allergen-specific T cells reveals TH2 heterogeneity in allergic individuals., PMID:34863852

X-linked CD40 ligand deficiency in a 1-year-old male Shih Tzu with secondary Pneumocystis pneumonia., PMID:33274522

Correlation between Intravoxel Incoherent Motion Magnetic Resonance Imaging Derived Metrics and Serum Soluble CD40 Ligand Level in an Embolic Canine Stroke Model., PMID:28860901

Th17-skewed immune response and cluster of differentiation 40 ligand expression in canine steroid-responsive meningitis-arteritis, a large animal model for neutrophilic meningitis., PMID:28114998

Suppression of Canine Dendritic Cell Activation/Maturation and Inflammatory Cytokine Release by Mesenchymal Stem Cells Occurs Through Multiple Distinct Biochemical Pathways., PMID:27842458

Human memory CD4+ T cell response to the major dog allergen Can f 5, prostatic kallikrein., PMID:26684878

Targeting the HA2 subunit of influenza A virus hemagglutinin via CD40L provides universal protection against diverse subtypes., PMID:25052763

CD40 ligand preferentially modulates immune response and enhances protection against influenza virus., PMID:24928989

A hexon and fiber-modified adenovirus expressing CD40L improves the antigen presentation capacity of dendritic cells., PMID:24598450

Production of canine soluble CD40 ligand to induce maturation of monocyte derived dendritic cells for cancer immunotherapy., PMID:24144681

Treatment efficacy and immune stimulation by AdCD40L gene therapy of spontaneous canine malignant melanoma., PMID:23799414

AdCD40L--crossing the valley of death?, PMID:22804573

Essential role of IL-4 and IL-4Rα interaction in adaptive immunity of zebrafish: insight into the origin of Th2-like regulatory mechanism in ancient vertebrates., PMID:22547699

CD40 ligand is necessary and sufficient to support primary diffuse large B-cell lymphoma cells in culture: a tool for in vitro preclinical studies with primary B-cell malignancies., PMID:22229753

Resistance of canine lymphoma cells to adenoviral infection due to reduced cell surface RGD binding integrins., PMID:21321486

Comparative analysis of canine monocyte- and bone-marrow-derived dendritic cells., PMID:20167201

A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific immune responses in vivo., PMID:19786146

Establishment of long-term tolerance to SRBC in dogs by recombinant canine CTLA4-Ig., PMID:19667932

Efficient adenovector CD40 ligand immunotherapy of canine malignant melanoma., PMID:18391758

Development and in vitro characterization of canine CD40-Ig., PMID:18387675

CD40 ligand supports the long-term maintenance and differentiation of chicken B cells in culture., PMID:18374414

Characterization of canine monocyte-derived dendritic cells with phenotypic and functional differentiation., PMID:17695590

CD154 blockade and donor-specific transfusions in DLA-identical marrow transplantation in dogs conditioned with 1-Gy total body irradiation., PMID:17241922

Targeting with bovine CD154 enhances humoral immune responses induced by a DNA vaccine in sheep., PMID:12517965

Gene therapy for hepatocellular carcinoma-teaching old dogs new tricks., PMID:11431753

In vitro IgE but not IgG production of canine peripheral blood B cells is inhibited by CD40 ligation., PMID:10889305

Datasheet
$ 480
Product specifications
100 μg 480 1 mg 2880

Contact Information

Order: order@antibodysystem.com

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Distributor list

For research use only. Not for human or drug use.

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Recombinant Dog CD154/CD40LG/TNFSF5 Protein, C-Fc [EQD85401]
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