Catalog No.
EQD85401
Expression system
Mammalian Cells
Species
Canis lupus familiaris (Dog) (Canis familiaris)
Protein length
Gln113-Leu260
Predicted molecular weight
44.04 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O97626
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD40 ligand, CD40-L, Tumor necrosis factor ligand superfamily member 5, CD154, CD40 ligand, membrane form, CD40 ligand, soluble form, sCD40L, CD40LG, CD40L, TNFSF5
Impact of artificial waterholes on temporal partitioning in a carnivore guild: a comparison of activity patterns at artificial waterholes to roads and trails., PMID:37159833
Single-cell characterization of dog allergen-specific T cells reveals TH2 heterogeneity in allergic individuals., PMID:34863852
X-linked CD40 ligand deficiency in a 1-year-old male Shih Tzu with secondary Pneumocystis pneumonia., PMID:33274522
Correlation between Intravoxel Incoherent Motion Magnetic Resonance Imaging Derived Metrics and Serum Soluble CD40 Ligand Level in an Embolic Canine Stroke Model., PMID:28860901
Th17-skewed immune response and cluster of differentiation 40 ligand expression in canine steroid-responsive meningitis-arteritis, a large animal model for neutrophilic meningitis., PMID:28114998
Suppression of Canine Dendritic Cell Activation/Maturation and Inflammatory Cytokine Release by Mesenchymal Stem Cells Occurs Through Multiple Distinct Biochemical Pathways., PMID:27842458
Human memory CD4+ T cell response to the major dog allergen Can f 5, prostatic kallikrein., PMID:26684878
Targeting the HA2 subunit of influenza A virus hemagglutinin via CD40L provides universal protection against diverse subtypes., PMID:25052763
CD40 ligand preferentially modulates immune response and enhances protection against influenza virus., PMID:24928989
A hexon and fiber-modified adenovirus expressing CD40L improves the antigen presentation capacity of dendritic cells., PMID:24598450
Production of canine soluble CD40 ligand to induce maturation of monocyte derived dendritic cells for cancer immunotherapy., PMID:24144681
Treatment efficacy and immune stimulation by AdCD40L gene therapy of spontaneous canine malignant melanoma., PMID:23799414
AdCD40L--crossing the valley of death?, PMID:22804573
Essential role of IL-4 and IL-4Rα interaction in adaptive immunity of zebrafish: insight into the origin of Th2-like regulatory mechanism in ancient vertebrates., PMID:22547699
CD40 ligand is necessary and sufficient to support primary diffuse large B-cell lymphoma cells in culture: a tool for in vitro preclinical studies with primary B-cell malignancies., PMID:22229753
Resistance of canine lymphoma cells to adenoviral infection due to reduced cell surface RGD binding integrins., PMID:21321486
Comparative analysis of canine monocyte- and bone-marrow-derived dendritic cells., PMID:20167201
A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific immune responses in vivo., PMID:19786146
Establishment of long-term tolerance to SRBC in dogs by recombinant canine CTLA4-Ig., PMID:19667932
Efficient adenovector CD40 ligand immunotherapy of canine malignant melanoma., PMID:18391758
Development and in vitro characterization of canine CD40-Ig., PMID:18387675
CD40 ligand supports the long-term maintenance and differentiation of chicken B cells in culture., PMID:18374414
Characterization of canine monocyte-derived dendritic cells with phenotypic and functional differentiation., PMID:17695590
CD154 blockade and donor-specific transfusions in DLA-identical marrow transplantation in dogs conditioned with 1-Gy total body irradiation., PMID:17241922
Targeting with bovine CD154 enhances humoral immune responses induced by a DNA vaccine in sheep., PMID:12517965
Gene therapy for hepatocellular carcinoma-teaching old dogs new tricks., PMID:11431753
In vitro IgE but not IgG production of canine peripheral blood B cells is inhibited by CD40 ligation., PMID:10889305
For research use only. Not for human or drug use.
