Catalog No.
PHJ47901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RARRES2 (Ala33-Lys158).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Chemerin,Retinoic acid receptor responder protein 2,Tazarotene-induced gene 2 protein,RAR-responsive protein TIG2,TIG2,RARRES2
Purification
Purified by antigen affinity column.
Accession
Q99969
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Chemerin promotes invasion of oral squamous cell carcinoma by stimulating IL-6 and TNF-α production via STAT3 activation., PMID:38520551
Chemerin causes lipid metabolic imbalance and induces passive lipid accumulation in human hepatoma cell line via the receptor GPR1., PMID:33887347
BIOMARKERS OF DISEASE ACTIVITY IN SYSTEMIC SCLEROSIS., PMID:33310967
Chemerin Reactivates PTEN and Suppresses PD-L1 in Tumor Cells via Modulation of a Novel CMKLR1-mediated Signaling Cascade., PMID:32605911
[Changes in serum levels of adipokine after treatment in children with Kawasaki disease]., PMID:31948525
Tocilizumab modulates serum levels of adiponectin and chemerin in patients with rheumatoid arthritis: potential cardiovascular protective role of IL-6 inhibition., PMID:30148441
Chemerin 156F, generated by chymase cleavage of prochemerin, is elevated in joint fluids of arthritis patients., PMID:29973268
Adipokines expression profile in liver, adipose tissue and muscle during chicken embryo development., PMID:29953882
Hepatic chemerin mRNA in morbidly obese patients with nonalcoholic fatty liver disease., PMID:29025245
Tumor Necrosis Factor-Alpha and the ERK Pathway Drive Chemerin Expression in Response to Hypoxia in Cultured Human Coronary Artery Endothelial Cells., PMID:27792771
Adipocyte-secreted chemerin is processed to a variety of isoforms and influences MMP3 and chemokine secretion through an NFkB-dependent mechanism., PMID:27461525
Development by Genetic Immunization of Monovalent Antibodies (Nanobodies) Behaving as Antagonists of the Human ChemR23 Receptor., PMID:26864035
Structure-function relationships in thrombin-activatable fibrinolysis inhibitor., PMID:26786060
Chemerin in renal dysfunction and cardiovascular disease., PMID:26545628
Chemerin promotes the proliferation and migration of vascular smooth muscle and increases mouse blood pressure., PMID:26254337
Increased expression of chemerin in squamous esophageal cancer myofibroblasts and role in recruitment of mesenchymal stromal cells., PMID:25127029
Interrelated reduction of chemerin and plasminogen activator inhibitor-1 serum levels in rheumatoid arthritis after interleukin-6 receptor blockade., PMID:24912961
CHEMERIN (RARRES2) decreases in vitro granulosa cell steroidogenesis and blocks oocyte meiotic progression in bovine species., PMID:24671882
Autoantibody induction and adipokine levels in patients with psoriasis treated with infliximab., PMID:23572429
Anti-TNF therapy reduces serum levels of chemerin in rheumatoid arthritis: a new mechanism by which anti-TNF might reduce inflammation., PMID:23460910
Stimulation of non-neuronal muscarinic receptors enhances chemerin/ChemR23 system in dysfunctional endothelial cells., PMID:23154239
Serum chemerin is increased in patients with chronic plaque psoriasis and normalizes following treatment with infliximab., PMID:23110708
A high serum concentration of chemerin in pustular dermatitis paradoxically induced by etanercept., PMID:22507591
Chemerin induces CCL2 and TLR4 in synovial fibroblasts of patients with rheumatoid arthritis and osteoarthritis., PMID:22037282
Chemerin158K protein is the dominant chemerin isoform in synovial and cerebrospinal fluids but not in plasma., PMID:21930706
Chemerin/ChemR23 signaling axis is involved in the endothelial protection by K(ATP) channel opener iptakalim., PMID:21516134
The possible role of ChemR23/Chemerin axis in the recruitment of dendritic cells in lupus nephritis., PMID:21346723
Human articular chondrocytes express ChemR23 and chemerin; ChemR23 promotes inflammatory signalling upon binding the ligand chemerin(21-157)., PMID:21192818
Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment., PMID:19114666
Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis., PMID:18794339
Resolvin E1 promotes mucosal surface clearance of neutrophils: a new paradigm for inflammatory resolution., PMID:17496159
Chemokine-like receptor 1 expression by macrophages in vivo: regulation by TGF-beta and TLR ligands., PMID:16863918
Chemokine-like receptor 1 expression and chemerin-directed chemotaxis distinguish plasmacytoid from myeloid dendritic cells in human blood., PMID:15611246
For research use only. Not for human or drug use.
