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Anti-CCL13/MCP-4 Polyclonal Antibody

Catalog #:   PHJ45201 Specific References (42) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q99616
Overview

Catalog No.

PHJ45201

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CCL13/MCP-4 (Gln24-Thr98).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

NCC-1,Small-inducible cytokine A13,MCP4,C-C motif chemokine 13,CCL13,MCP-4,CK-beta-10,Monocyte chemoattractant protein 4,NCC1,SCYA13,Monocyte chemotactic protein 4

Purification

Purified by antigen affinity column.

Accession

Q99616

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CCL13/MCP-4 antibody (PHJ45201) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 35 kDa
    Observed MW: 35 kDa
References

Effectiveness and cytokine profile of combined anti-vascular endothelial growth factor and corticosteroid therapy for chronic retinal vein occlusion., PMID:39825912

Lebrikizumab decreases type 2 inflammatory biomarker levels in patients with asthma: data from randomized phase 3 trials (LAVOLTA I and II)., PMID:39781908

Inhibition of Bruton's tyrosine kinase with PD-1 blockade modulates T cell activation in solid tumors., PMID:39513363

Pharmacodynamic, prognostic, and predictive biomarkers in severe and critical COVID-19 patients treated with sirukumab., PMID:39362933

Dupilumab-associated head and neck dermatitis shows a pronounced type 22 immune signature mediated by oligoclonally expanded T cells., PMID:38565563

Proteomic, miRNA and bacterial biomarker patterns in atopic dermatitis patients and their course upon anti-IL-4Rα therapy., PMID:38379385

Macrophage expressed tartrate-resistant acid phosphatase 5 promotes pulmonary fibrosis progression., PMID:38178705

Phase 2 randomized clinical trial of astegolimab in patients with moderate to severe atopic dermatitis., PMID:36041655

Onchocerca volvulus-specific antibody and cellular responses in onchocerciasis patients treated annually with ivermectin for 30 years and exposed to parasite transmission in central Togo., PMID:35503786

HMGB1 Promotes Lymphangiogenesis through the Activation of RAGE on M2 Macrophages in Laryngeal Squamous Cell Carcinoma., PMID:35280439

Echinococcus multilocularis specific antibody, systemic cytokine, and chemokine levels, as well as antigen-specific cellular responses in patients with progressive, stable, and cured alveolar echinococcosis: A 10-year follow-up., PMID:35108275

Transcriptomic Profiling of Tape-Strips From Moderate to Severe Atopic Dermatitis Patients Treated With Dupilumab., PMID:34405829

Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis., PMID:34404786

A Comprehensive Analysis of Immune Constituents in Blood and Bronchoalveolar Lavage Allows Identification of an Immune Signature of Severe Asthma in Children., PMID:34349761

Tape-Strip Proteomic Profiling of Atopic Dermatitis on Dupilumab Identifies Minimally Invasive Biomarkers., PMID:32849633

Chip-based serum proteomics approach to reveal the potential protein markers in the sub-acute stroke patients receiving the treatment of Ginkgo Diterpene Lactone Meglumine Injection., PMID:32413576

Possible Mechanisms of Eosinophil Accumulation in Eosinophilic Pneumonia., PMID:32326200

Increased cardiovascular and atherosclerosis markers in blood of older patients with atopic dermatitis., PMID:31622668

Cytokines and chemokines expression in serum of patients with neuromyelitis optica., PMID:30718956

Systemic Chemokine Levels with "Gut-Specific" Vedolizumab in Patients with Inflammatory Bowel Disease-A Pilot Study., PMID:28829369

An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium., PMID:28648867

Role of periostin, FENO, IL-13, lebrikzumab, other IL-13 antagonist and dual IL-4/IL-13 antagonist in asthma., PMID:24283478

Tocilizumab infusion therapy normalizes inflammation in sporadic ALS patients., PMID:23844337

Dose-ranging study of lebrikizumab in asthmatic patients not receiving inhaled steroids., PMID:23726041

Sjögren's syndrome autoantibodies provoke changes in gene expression profiles of inflammatory cytokines triggering a pathway involving TACE/NF-κB., PMID:22157716

Monocyte chemotactic protein-3 induces human coronary smooth muscle cell proliferation., PMID:21536288

Expression of chemokines and chemokine receptors in lesional and nonlesional upper skin of patients with atopic dermatitis., PMID:19767072

Therapeutic activities of intravenous immunoglobulins in multiple sclerosis involve modulation of chemokine expression., PMID:19217671

TP receptor-mediated release of eosinophil chemotactic activity from human bronchial smooth muscle cells., PMID:18950617

CDIP-2, a synthetic peptide derived from chemokine (C-C motif) ligand 13 (CCL13), ameliorates allergic airway inflammation., PMID:18336592

Early cutaneous gene transcription changes in adult atopic dermatitis and potential clinical implications., PMID:17181634

Elevated serum monocyte chemoattractant protein-4 and chronic inflammation in overweight subjects., PMID:16855189

Loss of histochemical identity in mast cells lacking carboxypeptidase A., PMID:15988029

In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity., PMID:15027495

Th1-biased tertiary lymphoid tissue supported by CXC chemokine ligand 13-producing stromal network in chronic lesions of autoimmune gastritis., PMID:14530361

Migration of human blood dendritic cells across endothelial cell monolayers: adhesion molecules and chemokines involved in subset-specific transmigration., PMID:12714579

Common and differential chemokine expression patterns in rs cells of NLP, EBV positive and negative classical Hodgkin lymphomas., PMID:12115499

Antichemokine immunotherapy for allergic diseases., PMID:11964742

Monocyte chemoattractant protein (MCP)-4 expression in the airways of patients with asthma. Induction in epithelial cells and mononuclear cells by proinflammatory cytokines., PMID:10934112

Migration of eosinophils across endothelial cell monolayers: interactions among IL-5, endothelial-activating cytokines, and C-C chemokines., PMID:10725746

Macrophage-derived chemokine induces human eosinophil chemotaxis in a CC chemokine receptor 3- and CC chemokine receptor 4-independent manner., PMID:10069890

High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines., PMID:9276730

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-CCL13/MCP-4 Polyclonal Antibody [PHJ45201]
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