Catalog No.
PHJ42401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human UCN2 (Phe28-Cys112).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Ucn II,Stresscopin-related peptide,SRP,Urocortin II,URP,Urocortin-related peptide,Urocortin-2,UCN2
Purification
Purified by antigen affinity column.
Accession
Q96RP3
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Interstitial lung disease is not rare in immune-mediated necrotizing myopathy with anti-signal recognition particle antibodies., PMID:35000598
The role of peripheral corticotropin-releasing factor signaling in a rat model of stress-induced gastric hyperalgesia., PMID:31558322
Recovery of respiratory function in mdx mice co-treated with neutralizing interleukin-6 receptor antibodies and urocortin-2., PMID:30160301
A mild myopathy with anti-SRP plus anti-PL-12 antibodies successfully treated by oral steroid monotherapy., PMID:29627033
A case of multiple sclerosis and necrotizing autoimmune myopathy with anti-SRP antibodies., PMID:29195113
Clinical features and prognosis in anti-SRP and anti-HMGCR necrotising myopathy., PMID:27147697
Immune-Mediated Necrotizing Myopathy: Update on Diagnosis and Management., PMID:26515574
Clinical Features and Treatment Outcomes of Necrotizing Autoimmune Myopathy., PMID:26192196
A His6-SUMO-eXact tag for producing human prepro-urocortin 2 in Escherichia coli for raising monoclonal antibodies., PMID:24291344
Urocortin 2 autocrine/paracrine and pharmacologic effects to activate AMP-activated protein kinase in the heart., PMID:24043794
Assessment of T regulatory cells and expanded profiling of autoantibodies may offer novel biomarkers for the clinical management of systemic sclerosis and undifferentiated connective tissue disease., PMID:23818915
Different effects of corticotropin-releasing factor and urocortin 2 on apoptosis of prostate cancer cells in vitro., PMID:21765100
Myositis or dystrophy? Traps and pitfalls., PMID:21377315
Activation of corticotropin-releasing factor 2 receptor inhibits Purkinje neuron P-type calcium currents via G(o)alpha-dependent PKC epsilon pathway., PMID:19439178
Structural determinants critical for localization and signaling within the seventh transmembrane domain of the type 1 corticotropin releasing hormone receptor: lessons from the receptor variant R1d., PMID:18772229
Urocortin 2 suppresses host resistance to Listeria monocytogenes infection via up-regulation of interleukin-10., PMID:16081642