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Anti-UCN2 Polyclonal Antibody

Catalog #:   PHJ42401 Specific References (16) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q96RP3
Overview

Catalog No.

PHJ42401

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human UCN2 (Phe28-Cys112).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Ucn II,Stresscopin-related peptide,SRP,Urocortin II,URP,Urocortin-related peptide,Urocortin-2,UCN2

Purification

Purified by antigen affinity column.

Accession

Q96RP3

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with UCN2 antibody (PHJ42401) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 36 kDa
    Observed MW: 36 kDa
References

Interstitial lung disease is not rare in immune-mediated necrotizing myopathy with anti-signal recognition particle antibodies., PMID:35000598

The role of peripheral corticotropin-releasing factor signaling in a rat model of stress-induced gastric hyperalgesia., PMID:31558322

Recovery of respiratory function in mdx mice co-treated with neutralizing interleukin-6 receptor antibodies and urocortin-2., PMID:30160301

A mild myopathy with anti-SRP plus anti-PL-12 antibodies successfully treated by oral steroid monotherapy., PMID:29627033

A case of multiple sclerosis and necrotizing autoimmune myopathy with anti-SRP antibodies., PMID:29195113

Clinical features and prognosis in anti-SRP and anti-HMGCR necrotising myopathy., PMID:27147697

Immune-Mediated Necrotizing Myopathy: Update on Diagnosis and Management., PMID:26515574

Clinical Features and Treatment Outcomes of Necrotizing Autoimmune Myopathy., PMID:26192196

A His6-SUMO-eXact tag for producing human prepro-urocortin 2 in Escherichia coli for raising monoclonal antibodies., PMID:24291344

Urocortin 2 autocrine/paracrine and pharmacologic effects to activate AMP-activated protein kinase in the heart., PMID:24043794

Assessment of T regulatory cells and expanded profiling of autoantibodies may offer novel biomarkers for the clinical management of systemic sclerosis and undifferentiated connective tissue disease., PMID:23818915

Different effects of corticotropin-releasing factor and urocortin 2 on apoptosis of prostate cancer cells in vitro., PMID:21765100

Myositis or dystrophy? Traps and pitfalls., PMID:21377315

Activation of corticotropin-releasing factor 2 receptor inhibits Purkinje neuron P-type calcium currents via G(o)alpha-dependent PKC epsilon pathway., PMID:19439178

Structural determinants critical for localization and signaling within the seventh transmembrane domain of the type 1 corticotropin releasing hormone receptor: lessons from the receptor variant R1d., PMID:18772229

Urocortin 2 suppresses host resistance to Listeria monocytogenes infection via up-regulation of interleukin-10., PMID:16081642

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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Distributor list

For research use only. Not for human or drug use.

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Anti-UCN2 Polyclonal Antibody [PHJ42401]
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