Catalog No.
MHD37902
Species reactivity
Human
Host species
Mouse
Isotype
IgG
Clonality
Monoclonal
Immunogen
Human AZU1/CAP37/HBP Protein.
Applications
CLIA, IFA, TIA
Target
Azurocidin, Cationic antimicrobial protein CAP37, Heparin-binding protein, HBP, hHBP, AZU1
Concentration
1mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
1A331
Note
For research use only.
Ligands of surface Ig raise cytoplasmic free Ca++ in human B cells., PMID:3878580
Azurocidin and a homologous serine protease from neutrophils. Differential antimicrobial and proteolytic properties., PMID:2312733
CAP37, a human neutrophil-derived chemotactic factor with monocyte specific activity., PMID:2332502
Complementary DNA sequence of human neutrophil azurocidin, an antibiotic with extensive homology to serine proteases., PMID:2049091
Comparison of granule proteins from human polymorphonuclear leukocytes which are bactericidal toward Pseudomonas aeruginosa., PMID:1937776
The in vitro effect of human polymorphonuclear leukocyte azurophil granule components on natural killer cell cytotoxicity., PMID:7936726
Structure of the azurocidin, proteinase 3, and neutrophil elastase genes. Implications for inflammation and vasculitis., PMID:7952651
Sperm immobilizing activity of a synthetic bioactive peptide 20-44 of 37-kDa cationic antimicrobial protein (CAP37) of human neutrophils., PMID:8575983
Azurocidin is a novel antigen for anti-neutrophil cytoplasmic autoantibodies (ANCA) in systemic vasculitis., PMID:8608637
Frequency of anti-bactericidal/permeability-increasing protein (BPI) and anti-azurocidin in patients with renal disease., PMID:8697620
CAP37, a neutrophil granule-derived protein stimulates protein kinase C activity in endothelial cells., PMID:8830799
Human leukocyte elastase is an endogenous ligand for the integrin CR3 (CD11b/CD18, Mac-1, alpha M beta 2) and modulates polymorphonuclear leukocyte adhesion., PMID:8879192
ANCA defines the clinical disease manifestations of vasculitis., PMID:8946586
Identification of human neutrophil-derived cathepsin G and azurocidin/CAP37 as chemoattractants for mononuclear cells and neutrophils., PMID:9271589
Pyoderma gangrenosum, polyarthritis and lung cysts with novel antineutrophil cytoplasmic antibodies to azurocidin., PMID:9767266
AZU-1: a candidate breast tumor suppressor and biomarker for tumor progression., PMID:10749935
Clinical associations and characterisation of antineutrophil cytoplasmic antibodies directed against bactericidal/permeability-increasing protein and azurocidin., PMID:10836522
Cloning and structural characterization of ECTACC, a new member of the transforming acidic coiled coil (TACC) gene family: cDNA sequence and expression analysis in human microvascular endothelial cells., PMID:11161455
Interaction of an uuter membrane protein of enterotoxigenic Escherichia coli with cell surface heparan sulfate proteoglycans., PMID:11854241
Borrelia burgdorferi are susceptible to killing by a variety of human polymorphonuclear leukocyte components., PMID:11920297
Isolation of non-heparin-binding and heparin-binding proteins of boar prostate., PMID:12013220
Arginine-rich cationic polypeptides amplify lipopolysaccharide-induced monocyte activation., PMID:12438368
ANCA against bactericidal/permeability-increasing protein, azurocidin, calprotectin and defensins in rheumatic and infectious diseases: prevalence and clinical associations., PMID:14740437
Azurocidin-specific-ANCA-related idiopathic necrotizing crescentic glomerulonephritis., PMID:15042565
Binding between azurocidin and calreticulin: its involvement in the activation of peripheral monocytes., PMID:15047718
Possible involvement of heparin-binding protein in transfusion-related acute lung injury., PMID:18346022
Identifying the functional part of heparin-binding protein (HBP) as a monocyte stimulator and the novel role of monocytes as HBP producers., PMID:20083497
Erysipelas caused by group A streptococcus activates the contact system and induces the release of heparin-binding protein., PMID:20107486
Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans., PMID:20133713
The proteomic profile of circulating pentraxin 3 (PTX3) complex in sepsis demonstrates the interaction with azurocidin 1 and other components of neutrophil extracellular traps., PMID:22278372
Leptospira interrogans shotgun phage display identified LigB as a heparin-binding protein., PMID:23044419
Myeloperoxidase directs properdin-mediated complement activation., PMID:24355864
Simple and Efficient Purification of Recombinant Proteins Using the Heparin-Binding Affinity Tag., PMID:29091276
The role of β2 integrin associated heparin-binding protein release in ARDS., PMID:29679701
Time-resolved fluorescent immunoassay-based combined detection of procalcitonin, C-reactive protein, heparin binding protein, and serum amyloid A1 to improve the diagnostic accuracy of early infection., PMID:30338547
ROP9, MIC3, and SAG2 are heparin-binding proteins in Toxoplasma gondii and involved in host cell attachment and invasion., PMID:30664845
Composition and physiological functions of the porcine colostrum., PMID:34409709
Azurocidin is loaded into small extracellular vesicles via its N-linked glycosylation and promotes intravasation of renal cell carcinoma cells., PMID:34418081
Establishment of heparin-binding protein time-resolved immunoassay and some potential clinical applications., PMID:34473955
Diagnostic Value of the Triple Combination of Serum Heparin-Binding Protein, Procalcitonin, and C-Reactive Protein in Children with Acute Bacterial Upper Respiratory Tract Infection., PMID:35310200
Development and application of amplified luminescent proximity homogeneous assay for quantitation of heparin-binding protein., PMID:36152874
Immune and inflammation: related factor alterations as biomarkers for predicting prognosis and responsiveness to PD-1 monoclonal antibodies in cervical cancer., PMID:36171464
Increased CAP37 Expression in Stable Chronic Obstructive Pulmonary Disease., PMID:36245028
Altered expression of MZB1 in periodontitis: A possible link to disease pathogenesis., PMID:37332260
Screening and Application of DNA Aptamers for Heparin-Binding Protein., PMID:38675537
For research use only. Not for human or drug use.
