Catalog No.
PHJ39401
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human OTUB1 (Met1-Lys271).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
OTU1,hOTU1,OTU domain-containing ubiquitin aldehyde-binding protein 1,Deubiquitinating enzyme OTUB1,Otubain-1,OTUB1,Ubiquitin-specific-processing protease OTUB1,Ubiquitin thioesterase OTUB1,OTB1
Purification
Purified by antigen affinity column.
Accession
Q96FW1
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A novel circular RNA confers trastuzumab resistance in human epidermal growth factor receptor 2-positive breast cancer through regulating ferroptosis., PMID:35234341
Activated Protein C Ameliorates Diabetic Cardiomyopathy via Modulating OTUB1/YB-1/MEF2B Axis., PMID:34778410
Deubiquitinating enzyme OTUB1 promotes cancer cell immunosuppression via preventing ER-associated degradation of immune checkpoint protein PD-L1., PMID:33328570
Amyloid aggregates of the deubiquitinase OTUB1 are neurotoxic, suggesting that they contribute to the development of Parkinson's disease., PMID:32005664
Preventing abnormal NF-κB activation and autoimmunity by Otub1-mediated p100 stabilization., PMID:31086255
Hydrazide Mimics for Protein Lysine Acylation To Assess Nucleosome Dynamics and Deubiquitinase Action., PMID:29991262
Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer., PMID:29326975
GRAIL and Otubain-1 are Related to T Cell Hyporesponsiveness during Trypanosoma cruzi Infection., PMID:28114324
OTUB1 overexpression in mesangial cells is a novel regulator in the pathogenesis of glomerulonephritis through the decrease of DCN level., PMID:22279542
For research use only. Not for human or drug use.
