Catalog No.
VHC94301
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Applications
ELISA, Neutralization
Target
Bone morphogenetic protein 4, BMP-4, Bone morphogenetic protein 2B, BMP-2B, BMP4, BMP2B, DVR4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P12644
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
6H4
Note
For research use only. Not suitable for clinical or therapeutic use.
Molecular events contributing to successful pediatric cardiac transplantation in HLA sensitized recipients., PMID:30710563
Photobiomodulation and gametogenic potential of human Wharton's jelly-derived mesenchymal cells., PMID:31029424
Enhanced chondrogenesis from human embryonic stem cells., PMID:31326745
[Influence of BMP4 on Regulation of Cell Cycle and Apoptosis of Hematopoietic Stem Cells/Progenitor Cells and Its Mechanism in Chemotherapy-Induced Myelosuppression]., PMID:31418391
Circulating noggin levels following treatment with denosumab or teriparatide in postmenopausal women with low bone mass., PMID:31475931
Analysis of the transcription factors and their regulatory roles during a step-by-step differentiation of induced pluripotent stem cells into hepatocyte-like cells., PMID:31612883
GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients., PMID:31694641
Role of bone morphogenetic protein-2/4 in astrocyte activation in neuropathic pain., PMID:31726923
Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia., PMID:31899794
A Role for MMP-10 (Matrix Metalloproteinase-10) in Calcific Aortic Valve Stenosis., PMID:32188274
Matrix Gla protein maintains normal and malignant hematopoietic progenitor cells by interacting with bone morphogenetic protein-4., PMID:32322728
Non-cell autonomous promotion of astrogenesis at late embryonic stages by constitutive YAP activation., PMID:32341445
The role of hepatocyte growth factor in mesenchymal stem cell-induced recovery in spinal cord injured rats., PMID:32410702
Disruption of BMP Signaling Prevents Hyperthyroidism-Induced Bone Loss in Male Mice., PMID:32453466
Eukaryotic expression, Co-IP and MS identify BMPR-1B protein-protein interaction network., PMID:32471519
A Synthetic Cell-Penetrating Heparin-Binding Peptide Derived from BMP4 with Anti-Inflammatory and Chondrogenic Functions for the Treatment of Arthritis., PMID:32549254
SOSTDC1 promotes invasion and liver metastasis in colorectal cancer via interaction with ALCAM/CD166., PMID:32801337
Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome., PMID:32896271
Stepwise differentiation and functional characterization of human induced pluripotent stem cell-derived choroidal endothelial cells., PMID:32967716
Prematurity negatively affects regenerative properties of human amniotic epithelial cells in the context of lung repair., PMID:33000862
Serum Cytokine Profiling Identifies Axl as a New Biomarker Candidate for Active Eosinophilic Granulomatosis With Polyangiitis., PMID:33987203
Specific Blockade of Bone Morphogenetic Protein-2/4 Induces Oligodendrogenesis and Remyelination in Demyelinating Disorders., PMID:34159538
Okadaic Acid Exposure Induced Neural Tube Defects in Chicken (Gallus gallus) Embryos., PMID:34199615
The promising effects of BMP2 transfected mesenchymal stem cells on human osteosarcoma., PMID:34377054
The role of bone morphogenetic protein 4 in corneal injury repair., PMID:34537186
Prostate tumor-induced stromal reprogramming generates Tenascin C that promotes prostate cancer metastasis through YAP/TAZ inhibition., PMID:34845375
Immunohistochemical analysis revealed the expression of bone morphogenetic proteins-4, 6, 7, and 9 in human induced membrane samples treated with the Masquelet technique., PMID:35033126
Precision-engineered niche for directed differentiation of MSCs to lineage-restricted mineralized tissues., PMID:35237403
Hair-follicle-associated pluripotent (HAP) stem cells differentiate into mature beating cardiomyocyte sheets on flexible substrates in vitro., PMID:35536435
Cardiac differentiation of human pluripotent stem cells using defined extracellular matrix proteins reveals essential role of fibronectin., PMID:35758861
Selective targeting BMP2 and 4 in SMAD4 negative esophageal adenocarcinoma inhibits tumor growth and aggressiveness in preclinical models., PMID:35902550
Neuroprotective and Regenerative Effects of Growth Hormone (GH) in the Embryonic Chicken Cerebral Pallium Exposed to Hypoxic-Ischemic (HI) Injury., PMID:36012320
Sputum Cytokine Profiling in COPD: Comparison Between Stable Disease and Exacerbation., PMID:36017119
CXCL16 inhibits epithelial regeneration and promotes fibrosis during the progression of radiation enteritis., PMID:36373877
Inhibition of BMP2 and BMP4 Represses Barrett's Esophagus While Enhancing the Regeneration of Squamous Epithelium in Preclinical Models., PMID:36706916
Osteogenic Potential of Autologous Dentin Graft Compared with Bovine Xenograft Mixed with Autologous Bone in the Esthetic Zone: Radiographic, Histologic and Immunohistochemical Evaluation., PMID:37047413
JNK Inhibition Modulates the Cytoskeleton, Hypoxia, and Neurogenesis on the Protein Level in Glioblastoma Cells and Astrocytes: An Immunofluorescence Study., PMID:37614213
Changes in the Expression of TGF-Beta Regulatory Pathway Genes Induced by Vitamin D in Patients with Relapsing-Remitting Multiple Sclerosis., PMID:37833895
Regulation of HHLA2 expression in kidney cancer and myeloid cells., PMID:37891555
Rat hair-follicle-associated pluripotent (HAP) stem cells can differentiate into atrial or ventricular cardiomyocytes in culture controlled by specific supplementation., PMID:38277391
Fluorescence-activated nuclear sorting (FANS) of nuclei from in vitro-generated syncytiotrophoblast., PMID:38944560
Bone morphogenic protein-4 availability in the cardiac microenvironment controls inflammation and fibrosis in autoimmune myocarditis., PMID:39196111
Cytokine profile of cerebrospinal fluid in pediatric patients with metastatic medulloblastoma., PMID:39524698
Single-cell transcriptome analysis reveals CD34 as a marker of human sinoatrial node pacemaker cardiomyocytes., PMID:39604360
Novel plasma cytokines identified and validated in children during lead exposure according to the new updated BLRV., PMID:39639084
Impact of Lysine to Methionine Ratios on Antioxidant Capacity and Immune Function in the Rumen of Tibetan Sheep: An RNA-Seq Analysis., PMID:39708312
AP2M1 as the potential biomarker for prediction of the response of atopic dermatitis to Dupilumab therapy: Multi-omics analysis and evidence., PMID:39818381
Non-Canonical Wnt16 and microRNA-145 Mediate the Response of Human Bone Marrow Stromal Cells to Additively Manufactured Porous 3-Dimensional Biomimetic Titanium-Aluminum-Vanadium Constructs., PMID:39937002
Intestinal mucosal transcriptomic responses of Asian seabass (Lates calcarifer) vaccinated with an oral hydrogel-encapsulated multivalent Vibrio antigen following Vibrio spp. infection., PMID:40252617
SOX2 Expression and Regulation in Pulmonary Aplasia/Agenesis., PMID:40528275