Catalog No.
PHF60301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RACK1 (Met1-Arg317).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
RACK1, Human lung cancer oncogene 7 protein, Guanine nucleotide-binding protein subunit beta-like protein 12.3, GNB2L1, Cell proliferation-inducing gene 21 protein, Guanine nucleotide-binding protein subunit beta-2-like 1, Receptor of activated protein C kinase 1, Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed, Receptor for activated C kinase, Small ribosomal subunit protein RACK1, HLC-7
Purification
Purified by antigen affinity column.
Accession
P63244
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
RACK1 promotes the development and function of alveolar macrophages through directly binding to and stabilizing PPARγ., PMID:40512793
An Antagonist Antibody That Inhibits Cancer Cell Growth In Vitro through RACK1., PMID:39458945
Rack1 regulates B-cell development and function by binding to and stabilizing the transcription factor Pax5., PMID:39256480
RACK1 enhances STAT3 stability and promotes T follicular helper cell development and function during blood-stage Plasmodium infection in mice., PMID:39024388
Toxoplasma gondii surface antigen 1 (SAG1) interacts in vitro with host cell receptor for activated C kinase 1 (RACK1)., PMID:38157925
Targeting RACK1 to alleviate TDP-43 and FUS proteinopathy-mediated suppression of protein translation and neurodegeneration., PMID:38111057
Longitudinal transcriptional analysis of peripheral blood leukocytes in COVID-19 convalescent donors., PMID:36510222
Hepatic RACK1 deficiency protects against fulminant hepatitis through myeloid-derived suppressor cells., PMID:35265209
Invariable Ribosome Stoichiometry During Murine Erythroid Differentiation: Implications for Understanding Ribosomopathies., PMID:35187080
Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells., PMID:34469723
Integrin β3, a RACK1 interacting protein, is critical for porcine reproductive and respiratory syndrome virus infection and NF-κB activation in Marc-145 cells., PMID:32247758
Rack1 Controls Parallel Fiber-Purkinje Cell Synaptogenesis and Synaptic Transmission., PMID:31920545
Voltage-Dependent Anion Channel Protein 2 (VDAC2) and Receptor of Activated Protein C Kinase 1 (RACK1) Act as Functional Receptors for Lymphocystis Disease Virus Infection., PMID:30918079
Opposite regulation of Wnt/β-catenin and Shh signaling pathways by Rack1 controls mammalian cerebellar development., PMID:30765517
RACK1 deficiency synergizes with all-trans retinoic acid to induce apoptosis in human acute promyelocytic leukemia cells., PMID:30019299
A label-free electrochemical biosensor for direct detection of RACK 1 by using disposable, low-cost and reproducible ITO based electrode., PMID:29776548
Interaction of the Mineralocorticoid Receptor With RACK1 and Its Role in Aldosterone Signaling., PMID:28472300
Integrin beta and receptor for activated protein kinase C are involved in the cell entry of Bombyx mori cypovirus., PMID:28175946
Label-free, ITO-based immunosensor for the detection of a cancer biomarker: Receptor for Activated C Kinase 1., PMID:27454557
Inhibition of RACK1 ameliorates choroidal neovascularization formation in vitro and in vivo., PMID:27112838
Ion channel TRPM8 promotes hypoxic growth of prostate cancer cells via an O2 -independent and RACK1-mediated mechanism of HIF-1α stabilization., PMID:25065497
A multiparametric serum marker panel as a complementary test to mammography for the diagnosis of node-negative early-stage breast cancer and DCIS in young women., PMID:24957886
Essential function for PDLIM2 in cell polarization in three-dimensional cultures by feedback regulation of the β1-integrin-RhoA signaling axis., PMID:24863845
Luteolin sensitizes the antiproliferative effect of interferon α/β by activation of Janus kinase/signal transducer and activator of transcription pathway signaling through protein kinase A-mediated inhibition of protein tyrosine phosphatase SHP-2 in cancer cells., PMID:24333668
Cancer-derived immunoglobulin G promotes tumor cell growth and proliferation through inducing production of reactive oxygen species., PMID:24309932
Early activation of nSMase2/ceramide pathway in astrocytes is involved in ischemia-associated neuronal damage via inflammation in rat hippocampi., PMID:24007266
Up-regulation of RACK1 by TGF-β1 promotes hepatic fibrosis in mice., PMID:23555900
RACK1 identified as the PCBP1-interacting protein with a novel functional role on the regulation of human MOR gene expression., PMID:23173782
Identification and validation of new autoantibodies for the diagnosis of DCIS and node negative early-stage breast cancers., PMID:22886747
Overexpressions of RACK1 and CD147 associated with poor prognosis in stage T1 pulmonary adenocarcinoma., PMID:22592183
Tagging of functional ribosomes in living cells by HaloTag® technology., PMID:21082278
A synergistic approach to protein crystallization: combination of a fixed-arm carrier with surface entropy reduction., PMID:20196072
Expression of RACK1 is a novel biomarker in pulmonary adenocarcinomas., PMID:19892429
Epstein-Barr virus BART gene expression., PMID:19141439
mrtl-A translation/localization regulatory protein encoded within the human c-myc locus and distributed throughout the endoplasmic and nucleoplasmic reticular network., PMID:18816594
The Opitz syndrome gene product MID1 assembles a microtubule-associated ribonucleoprotein complex., PMID:18172692
Characterization of IQGAP1-containing complexes in NK-like cells: evidence for Rac 2 and RACK1 association during homotypic adhesion., PMID:17269730
Cell-specific expression of the epm1 (cystatin B) gene in developing rat cerebellum., PMID:16137571
RACK1 mediates activation of JNK by protein kinase C [corrected]., PMID:16061178
Identification of the linker histone H1 as a protein kinase Cepsilon-binding protein in vascular smooth muscle., PMID:15499382
Identification and characterization of the human ARD1-NATH protein acetyltransferase complex., PMID:15496142
Aging-related alterations in the distribution of Ca(2+)-dependent PKC isoforms in rabbit hippocampus., PMID:15382255
Ki-1/57 interacts with RACK1 and is a substrate for the phosphorylation by phorbol 12-myristate 13-acetate-activated protein kinase C., PMID:14699138
Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly., PMID:14654845
Protein kinase C isoforms in the enteric nervous system., PMID:12811573
Measles virus suppresses interferon-alpha signaling pathway: suppression of Jak1 phosphorylation and association of viral accessory proteins, C and V, with interferon-alpha receptor complex., PMID:12620806
Effects of prenyl pyrophosphates on the binding of PKCgamma with RACK1., PMID:12506405
Activation of Integrin-RACK1/PKCalpha signalling in human articular chondrocyte mechanotransduction., PMID:12435334
New insights into the molecular basis of progressive myoclonus epilepsy: a multiprotein complex with cystatin B., PMID:12393805
The betagamma subunit of heterotrimeric G proteins interacts with RACK1 and two other WD repeat proteins., PMID:12359736
For research use only. Not for human or drug use.
