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Anti-Human CD84 Polyclonal Antibody

Catalog #:   PHJ77502 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q9UIB8
Overview

Catalog No.

PHJ77502

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD84 (Lys22-Gly225).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Signaling lymphocytic activation molecule 5, Hly9-beta, Cell surface antigen MAX.3, Leukocyte differentiation antigen CD84, CD84, SLAM family member 5, SLAMF5

Purification

Purified by antigen affinity column.

Accession

Q9UIB8

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CD84 antibody (PHJ77502) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 39 kDa
    Observed MW: 39 kDa
References

Targeting CD84 protein on myeloid-derived suppressor cells as a novel immunotherapy in solid tumors., PMID:39847992

Depletion of myeloid-derived suppressor cells sensitizes murine multiple myeloma to PD-1 checkpoint inhibitors., PMID:39755583

CD84 as a therapeutic target for breaking immune tolerance in triple-negative breast cancer., PMID:39466774

In vivo Bruton's tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis., PMID:39110779

Impact of Functional Polymorphisms on Drug Survival of Biological Therapies in Patients with Moderate-to-Severe Psoriasis., PMID:37240048

NanoString technology distinguishes anti-TIF-1γ+ from anti-Mi-2+ dermatomyositis patients., PMID:34043263

A New Hope for CD56negCD16pos NK Cells as Unconventional Cytotoxic Mediators: An Adaptation to Chronic Diseases., PMID:32373555

Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity., PMID:29337666

Ibrutinib and idelalisib block immunophenotypic changes associated with the adhesion and activation of CLL cells in the tumor microenvironment., PMID:29164976

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis., PMID:28150777

Slamf6 negatively regulates autoimmunity., PMID:27368806

Polymorphisms in CD84, IL12B and TNFAIP3 are associated with response to biologics in patients with psoriasis., PMID:27564082

Cell surface phenotype profiles distinguish stable and progressive chronic lymphocytic leukemia., PMID:24289109

Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis., PMID:23555300

[Some considerations of immune metabolism at preeclampsia]., PMID:22306495

Susceptibility loci for the defective foreign protein-induced tolerance in New Zealand Black mice: implication of epistatic effects of Fcgr2b and Slam family genes., PMID:21604261

New targets of pemphigus vulgaris antibodies identified by protein array technology., PMID:21255096

Expression of SLAM (CD150) cell-surface receptors on human B-cell subsets: from pro-B to plasma cells., PMID:20933013

Analysis of HLDA9 mAbs on plasmacytoid dendritic cells., PMID:20933012

Differential expression of SLAMS and other modulatory molecules by human plasma cells during normal maturation., PMID:20923684

Mouse CD84 is a pan-leukocyte cell-surface molecule that modulates LPS-induced cytokine secretion by macrophages., PMID:20628063

The leukocyte receptor CD84 inhibits Fc epsilon RI-mediated signaling through homophilic interaction in transfected RBL-2H3 cells., PMID:18243321

Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules., PMID:17201683

Extensive flow cytometric characterization of plasmacytoid dendritic cell leukemia cells., PMID:16146542

Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling., PMID:16037392

Molecular and cellular pathogenesis of X-linked lymphoproliferative disease., PMID:15661030

2B4 (CD244) is expressed and functional on human eosinophils., PMID:15611233

Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4)., PMID:15245368

Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells., PMID:15162436

Functional requirements for interactions between CD84 and Src homology 2 domain-containing proteins and their contribution to human T cell activation., PMID:12928397

Mouse novel Ly9: a new member of the expanding CD150 (SLAM) family of leukocyte cell-surface receptors., PMID:12242590

CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2., PMID:12115647

Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family., PMID:11862385

Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells., PMID:11689425

CD84 functions as a homophilic adhesion molecule and enhances IFN-gamma secretion: adhesion is mediated by Ig-like domain 1., PMID:11564780

Activation of lymphocytes inhibits human monocyte to macrophage differentiation., PMID:11563672

CD150 is a member of a family of genes that encode glycoproteins on the surface of hematopoietic cells., PMID:11486275

Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family., PMID:11414741

Genetic approach to insight into the immunobiology of human dendritic cells and identification of CD84-H1, a novel CD84 homologue., PMID:11300479

The transmembrane form of the CX3CL1 chemokine fractalkine is expressed predominantly by epithelial cells in vivo., PMID:11238035

CD84., PMID:11215822

2B4-mediated activation of human natural killer cells., PMID:11163399

Gene structure of the mouse leukocyte cell surface molecule Ly9., PMID:10970093

The CD2-subset of the Ig superfamily of cell surface molecules: receptor-ligand pairs expressed by NK cells and other immune cells., PMID:10764623

Characterization of MAX.3 antigen, a glycoprotein expressed on mature macrophages, dendritic cells and blood platelets: identity with CD84., PMID:10698700

2B4: an NK cell activating receptor with unique specificity and signal transduction mechanism., PMID:10658976

Molecular cloning and biological characterization of NK cell activation-inducing ligand, a counterstructure for CD48., PMID:10556801

Gene structure of the murine NK cell receptor 2B4: presence of two alternatively spliced isoforms with distinct cytoplasmic domains., PMID:10458751

Molecular characterization of a novel human natural killer cell receptor homologous to mouse 2B4., PMID:10458320

Phenotypic characterization of human skin mast cells by combined staining with toluidine blue and CD antibodies., PMID:9764855

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human CD84 Polyclonal Antibody [PHJ77502]
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