Catalog No.
PHJ77502
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD84 (Lys22-Gly225).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Signaling lymphocytic activation molecule 5, Hly9-beta, Cell surface antigen MAX.3, Leukocyte differentiation antigen CD84, CD84, SLAM family member 5, SLAMF5
Purification
Purified by antigen affinity column.
Accession
Q9UIB8
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Targeting CD84 protein on myeloid-derived suppressor cells as a novel immunotherapy in solid tumors., PMID:39847992
Depletion of myeloid-derived suppressor cells sensitizes murine multiple myeloma to PD-1 checkpoint inhibitors., PMID:39755583
CD84 as a therapeutic target for breaking immune tolerance in triple-negative breast cancer., PMID:39466774
In vivo Bruton's tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis., PMID:39110779
Impact of Functional Polymorphisms on Drug Survival of Biological Therapies in Patients with Moderate-to-Severe Psoriasis., PMID:37240048
NanoString technology distinguishes anti-TIF-1γ+ from anti-Mi-2+ dermatomyositis patients., PMID:34043263
A New Hope for CD56negCD16pos NK Cells as Unconventional Cytotoxic Mediators: An Adaptation to Chronic Diseases., PMID:32373555
Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity., PMID:29337666
Ibrutinib and idelalisib block immunophenotypic changes associated with the adhesion and activation of CLL cells in the tumor microenvironment., PMID:29164976
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis., PMID:28150777
Slamf6 negatively regulates autoimmunity., PMID:27368806
Polymorphisms in CD84, IL12B and TNFAIP3 are associated with response to biologics in patients with psoriasis., PMID:27564082
Cell surface phenotype profiles distinguish stable and progressive chronic lymphocytic leukemia., PMID:24289109
Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis., PMID:23555300
[Some considerations of immune metabolism at preeclampsia]., PMID:22306495
Susceptibility loci for the defective foreign protein-induced tolerance in New Zealand Black mice: implication of epistatic effects of Fcgr2b and Slam family genes., PMID:21604261
New targets of pemphigus vulgaris antibodies identified by protein array technology., PMID:21255096
Expression of SLAM (CD150) cell-surface receptors on human B-cell subsets: from pro-B to plasma cells., PMID:20933013
Analysis of HLDA9 mAbs on plasmacytoid dendritic cells., PMID:20933012
Differential expression of SLAMS and other modulatory molecules by human plasma cells during normal maturation., PMID:20923684
Mouse CD84 is a pan-leukocyte cell-surface molecule that modulates LPS-induced cytokine secretion by macrophages., PMID:20628063
The leukocyte receptor CD84 inhibits Fc epsilon RI-mediated signaling through homophilic interaction in transfected RBL-2H3 cells., PMID:18243321
Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules., PMID:17201683
Extensive flow cytometric characterization of plasmacytoid dendritic cell leukemia cells., PMID:16146542
Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling., PMID:16037392
Molecular and cellular pathogenesis of X-linked lymphoproliferative disease., PMID:15661030
2B4 (CD244) is expressed and functional on human eosinophils., PMID:15611233
Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4)., PMID:15245368
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells., PMID:15162436
Functional requirements for interactions between CD84 and Src homology 2 domain-containing proteins and their contribution to human T cell activation., PMID:12928397
Mouse novel Ly9: a new member of the expanding CD150 (SLAM) family of leukocyte cell-surface receptors., PMID:12242590
CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2., PMID:12115647
Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family., PMID:11862385
Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells., PMID:11689425
CD84 functions as a homophilic adhesion molecule and enhances IFN-gamma secretion: adhesion is mediated by Ig-like domain 1., PMID:11564780
Activation of lymphocytes inhibits human monocyte to macrophage differentiation., PMID:11563672
CD150 is a member of a family of genes that encode glycoproteins on the surface of hematopoietic cells., PMID:11486275
Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family., PMID:11414741
Genetic approach to insight into the immunobiology of human dendritic cells and identification of CD84-H1, a novel CD84 homologue., PMID:11300479
The transmembrane form of the CX3CL1 chemokine fractalkine is expressed predominantly by epithelial cells in vivo., PMID:11238035
CD84., PMID:11215822
2B4-mediated activation of human natural killer cells., PMID:11163399
Gene structure of the mouse leukocyte cell surface molecule Ly9., PMID:10970093
The CD2-subset of the Ig superfamily of cell surface molecules: receptor-ligand pairs expressed by NK cells and other immune cells., PMID:10764623
Characterization of MAX.3 antigen, a glycoprotein expressed on mature macrophages, dendritic cells and blood platelets: identity with CD84., PMID:10698700
2B4: an NK cell activating receptor with unique specificity and signal transduction mechanism., PMID:10658976
Molecular cloning and biological characterization of NK cell activation-inducing ligand, a counterstructure for CD48., PMID:10556801
Gene structure of the murine NK cell receptor 2B4: presence of two alternatively spliced isoforms with distinct cytoplasmic domains., PMID:10458751
Molecular characterization of a novel human natural killer cell receptor homologous to mouse 2B4., PMID:10458320
Phenotypic characterization of human skin mast cells by combined staining with toluidine blue and CD antibodies., PMID:9764855
For research use only. Not for human or drug use.
