Anti-Human DCK Polyclonal Antibody

Catalog No.

PHD75001

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human DCK (Met1-Leu260).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

dCK, Deoxyguanosine kinase, Deoxycytidine kinase, Deoxyadenosine kinase, DCK

Purification

Purified by antigen affinity column.

Accession

P27707

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

QSP modeling of loncastuximab tesirine with T-cell-dependent bispecific antibodies guides dose-regimen strategy., PMID:40500294

The Results of ADVANCE-CIDP IVIG Trial: Intravenous Immunoglobulin 10% Therapy With GAMMAGARD LIQUID/Kiovig for Treatment of Relapse in Chronic Inflammatory Demyelinating Polyradiculoneuropathy., PMID:40247653

Exploring autoantigens in autoimmune limbic encephalitis using phage immunoprecipitation sequencing., PMID:40133514

Bivalent RSVpreF Vaccine in Adults 18 to <60 Years Old With High-Risk Conditions., PMID:39523547

Respiratory Syncytial Virus Prefusion F Vaccination: Antibody Persistence and Revaccination., PMID:38606958

Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease., PMID:38589621

A Bivalent Omicron-BA.4/BA.5-Adapted BNT162b2 Booster in ≥12-Year-Olds., PMID:38016021

Utility of physiologically based pharmacokinetic modeling to predict inter-antibody variability in monoclonal antibody pharmacokinetics in mice., PMID:37824334

CD98hc is a target for brain delivery of biotherapeutics., PMID:37598178

Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages., PMID:36630914

PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells., PMID:36171284

COVID-19 rebound after Paxlovid treatment during Omicron BA.5 vs BA.2.12.1 subvariant predominance period., PMID:35982673

Neutralization of Omicron sublineages and Deltacron SARS-CoV-2 by three doses of BNT162b2 vaccine or BA.1 infection., PMID:35792746

Neutralization of Omicron BA.1, BA.2, and BA.3 SARS-CoV-2 by 3 doses of BNT162b2 vaccine., PMID:35739094

BNT162b2-elicited neutralization of Delta plus, Lambda, Mu, B.1.1.519, and Theta SARS-CoV-2 variants., PMID:35396516

Neutralization and durability of 2 or 3 doses of the BNT162b2 vaccine against Omicron SARS-CoV-2., PMID:35245438

GnRH receptor-activating autoantibodies in polycystic ovary syndrome: identification of functional epitopes and development of epitope mimetic inhibitors., PMID:34807394

RhCMV serostatus and vaccine adjuvant impact immunogenicity of RhCMV/SIV vaccines., PMID:32820216

Modulating tumor immunity by metronomic dosing of oxaliplatin incorporated in multiple oral nanoemulsion., PMID:32169534

Malaria vaccine candidate based on Duffy-binding protein elicits strain transcending functional antibodies in a Phase I trial., PMID:30302285

Examination of Hypoxanthine Guanine Phosphoribosyltransferase as a biomarker for colorectal cancer patients., PMID:30250925

Metuzumab enhanced chemosensitivity and apoptosis in non-small cell lung carcinoma., PMID:28055291

β1-Adrenergic and M2 Muscarinic Autoantibodies and Thyroid Hormone Facilitate Induction of Atrial Fibrillation in Male Rabbits., PMID:26517045

A peptidomimetic inhibitor suppresses the inducibility of β1-adrenergic autoantibody-mediated cardiac arrhythmias in the rabbit., PMID:26446828

AT2R autoantibodies block angiotensin II and AT1R autoantibody-induced vasoconstriction., PMID:26259590

Novel retro-inverso peptide inhibitor reverses angiotensin receptor autoantibody-induced hypertension in the rabbit., PMID:25691619

A compendium of strategies to prevent healthcare-associated infections in acute care hospitals: 2014 updates., PMID:25026611

Downregulation of deoxycytidine kinase in cytarabine-resistant mantle cell lymphoma cells confers cross-resistance to nucleoside analogs gemcitabine, fludarabine and cladribine, but not to other classes of anti-lymphoma agents., PMID:24972933

Prevalence of clinically significant red blood cell alloantibodies in pregnant women at a large tertiary-care facility., PMID:24689681

Shortened estrous cycle length, increased FSH levels, FSH variance, oocyte spindle aberrations, and early declining fertility in aging senescence-accelerated mouse prone-8 (SAMP8) mice: concomitant characteristics of human midlife female reproductive aging., PMID:24654787

Autoimmune mechanisms activating the angiotensin AT1 receptor in 'primary' aldosteronism., PMID:24552217

Metabolism of novel anti-HIV agent 3-cyanomethyl-4-methyl-DCK by human liver microsomes and recombinant CYP enzymes., PMID:21970838

Ribonucleotide reductase subunit M1 assessed by quantitative double-fluorescence immunohistochemistry predicts the efficacy of gemcitabine in biliary tract carcinoma., PMID:20811706

Expression of the human concentrative nucleotide transporter 1 (hCNT1) gene correlates with clinical response in patients affected by Waldenström's Macroglobulinemia (WM) and small lymphocytic lymphoma (SLL) undergoing a combination treatment with 2-chloro-2'-deoxyadenosine (2-CdA) and Rituximab., PMID:19647871

TLR7-dependent and FcgammaR-independent production of type I interferon in experimental mouse lupus., PMID:19047436

Methoxylation of 3',4'-aromatic side chains improves P-glycoprotein inhibitory and multidrug resistance reversal activities of 7,8-pyranocoumarin against cancer cells., PMID:18313307

Positive regulation of deoxycytidine kinase activity by phosphorylation of Ser-74 in B-cell chronic lymphocytic leukaemia lymphocytes., PMID:17350163

Cytosine arabinoside-metabolizing enzyme genes are underexpressed in children with MLL gene-rearranged acute lymphoblastic leukemia., PMID:17146554

(+/-)-3'-O, 4'-O-dicynnamoyl-cis-khellactone, a derivative of (+/-)-praeruptorin A, reverses P-glycoprotein mediated multidrug resistance in cancer cells., PMID:16875827

Identification of in vivo phosphorylation sites on human deoxycytidine kinase. Role of Ser-74 in the control of enzyme activity., PMID:16361699

Immunocytochemical detection of deoxycytidine kinase in haematological malignancies and solid tumours., PMID:15976334

Activation of deoxycytidine kinase in lymphocytes is calcium dependent and involves a conformational change detectable by native immunostaining., PMID:15104248

Physical and functional interactions between USF and Sp1 proteins regulate human deoxycytidine kinase promoter activity., PMID:14514691

Purine metabolism in leukocytes and erythrocytes in Graves' or Hashimoto's disease., PMID:12489570

Role of deoxycytidine kinase (dCK) activity in gemcitabine's radioenhancement in mice and human cell lines in vitro., PMID:12142097

Molecular and biochemical mechanisms of fludarabine and cladribine resistance in a human promyelocytic cell line., PMID:10606241

The intracellular localization of deoxycytidine kinase., PMID:9804782

A synaptic membrane glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein: isolation and immunochemical characterization., PMID:8939461

Induction of resistance to 2',2'-difluorodeoxycytidine in the human ovarian cancer cell line A2780., PMID:7481843

Development and molecular characterization of a 2',2'-difluorodeoxycytidine-resistant variant of the human ovarian carcinoma cell line A2780., PMID:8033147

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