Catalog No.
EHJ61602
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Lys62-Ala404
Predicted molecular weight
42.3kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NNX6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD209, DC-SIGN1, Dendritic cell-specific ICAM-3-grabbing non-integrin 1, CD209 antigen, CLEC4L, DC-SIGN, C-type lectin domain family 4 member L
Unraveling the Potential Role of SIGNR1(CD209b) in Shaping Gut Microbiota During the Early Postnatal Life., PMID:40470604
Proteomic characteristics of bronchoalveolar lavage fluid in children with mild and severe Mycoplasma pneumoniae pneumonia., PMID:40458711
The evaluation of a novel multi-epitope vaccine against human papillomavirus and Candida albicans., PMID:40390500
Molecular determinants of sialylated IgG anti-inflammatory activity., PMID:40377989
Lewis-X-Containing Triterpenoid Saponins Inhibit DC-SIGN- and L-SIGN-Mediated Transfer of HIV-1 Infection., PMID:40277287
SIRPα + CD209 + cell: a specialized antigen-presenting cell that contributes to anti-SIRPα/RT therapy in colorectal cancer., PMID:40208335
Mediators of the causal associations between protein ratios and ischemic stroke: a two-step Mendelian randomization study., PMID:40181221
Fucosyl glycosides for DC-SIGN targeting: Fucosylation strategies, synthesis and binding studies of model compounds., PMID:40147363
MCP-1 Reduction by L-SIGN Expression in Dengue Virus-Infected Liver Endothelial Cells., PMID:40143272
Urine of Cats with Severe Fever with Thrombocytopenia Syndrome: A Potential Source of Infection Transmission., PMID:40137739
CD209d/e are required for macrophage-mediated phagocytosis and activation during methicillin-resistant Staphylococcus aureus pulmonary host defense., PMID:40101753
Antitumor immune response elicited by M2 TAM-specific DDS via C-type lectin CD209b using cholesteryl pullulan nanogel as a protein drug carrier., PMID:40094910
Development of Anti-Inflammatory Agents Utilizing DC-SIGN Mediated IL-10 Secretion in Autoimmune and Immune-Mediated Disorders: Bridging Veterinary and Human Health., PMID:40076949
Autologous adipose-derived tissue stromal vascular fraction and intralesional epidermal growth factor combined application in patients with diabetic foot., PMID:40056382
The characterization of technical design of a virus-like structure (VLS) nanodelivery system as vaccine candidate against SARS-CoV-2 variants., PMID:40045463
Placental malaria infection is associated with downregulation of STAT-6 and ANG-1 in decidual macrophages., PMID:40007543
"Mannose glycans as key players in trained immunity: A novel anti-tumoral catalyst"., PMID:39988110
Computational insights into DC-SIGN's enhanced recognition of mannotriose CPS units via Ca2+ ion cross-talk., PMID:39969661
Glycan-Silica Nanoparticles as Effective Inhibitors for Blocking Virus Infection., PMID:39908032
Effect of repurposed metabolic drugs on human macrophage polarization and antitumoral activity., PMID:39889896
Identification of CD209 as an Intervention Target for Type 2 Diabetes After COVID-19 Infection: Insights From Proteome-Wide Mendelian Randomization., PMID:39874030
Comparative transcriptome analysis reveals a serotype-specific immune response in Nile tilapia (Oreochromis niloticus) infected with Streptococcus agalactiae., PMID:39867881
CD209d/e promotes inflammation and lung injury during influenza virus infection., PMID:39846844
Changes in the Phenotype and Metabolism of Peritoneal Macrophages in Mucin-2 Knockout Mice and Partial Restoration of Their Functions In Vitro After L-Fucose Treatment., PMID:39795876
Host cell lectins ASGR1 and DC-SIGN jointly with TMEM106B confer ACE2 independence and imdevimab resistance to SARS-CoV-2 pseudovirus with spike mutation E484D., PMID:39791910
Simultaneous Blockade of CD209 and CD209L by Monoclonal Antibody Does Not Provide Sufficient Protection Against Multiple Viral Infections In Vivo., PMID:39783143
Lactobacillus crispatus S-layer proteins modulate innate immune response and inflammation in the lower female reproductive tract., PMID:39737998
Autoantibodies in hospitalised patients with COVID-19., PMID:39734590
Polarization and Characterization of M1 and M2 Human Monocyte-Derived Macrophages on Implant Surfaces., PMID:39714038
Homocysteine affects macrophage polarization by altering m6A methylation of scavenger receptors CD209 and CD163L1., PMID:39627020
Identification and functional characterization of CD209 homologous genes in zebrafish., PMID:39557479
Development of a candidate vaccine against severe fever with thrombocytopenia syndrome virus using Gn/Gc glycoprotein via multiple expression vectors delivered by attenuated Salmonella confers effective protection in hDC-SIGN transduced mice., PMID:39547019
Sialylated IgG induces the transcription factor REST in alveolar macrophages to protect against lung inflammation and severe influenza disease., PMID:39541970
Short- and long-term immunosuppressive effects of melanoma influence the prognostic value of the sentinel lymph node status., PMID:39388865
Differential proteins from EVs identification based on tandem mass tags analysis and effect of Treg-derived EVs on T-lymphocytes in COPD patients., PMID:39342213
Soluble isoforms of the DC-SIGN receptor can increase the dengue virus infection in immature dendritic cells., PMID:39341603
Carbohydrate-Lectin Interactions Reprogram Dendritic Cells to Promote Type 1 Anti-Tumor Immunity., PMID:39283240
Extracellular Silica Nanomatrices Promote In Vitro Maturation of Anti-tumor Dendritic Cells via Activation of Focal Adhesion Kinase., PMID:39268785
Development and characterization of dendritic cell internalization and activation assays contributing to the immunogenicity risk evaluation of biotherapeutics., PMID:39229274
The Molecular Signature Related to Local Inflammatory and Immune Response in Canine Cutaneous Hypersensitivity Reactions: A Preliminary Study., PMID:39194759
Profiling dendritic cells subsets in renal tissue of patients with crescentic glomerulonephritis., PMID:39069601
Combinatorial macrophage induced innate immunotherapy against Ewing sarcoma: Turning "Two Keys" simultaneously., PMID:38992659
Probing scaffold size effects on multivalent lectin-glycan binding affinity, thermodynamics and antiviral properties using polyvalent glycan-gold nanoparticles., PMID:38984502
Validating genetic variants in innate immunity linked to infectious events in acute myeloid leukemia post-induction chemotherapy., PMID:38982248
Exosomes multiplex profiling, a promising strategy for early diagnosis of laryngeal cancer., PMID:38902710
Carboxylesterase 1 directs the metabolic profile of dendritic cells to a reduced inflammatory phenotype., PMID:38869086
Differences in IDO1+ dendritic cells and soluble CTLA-4 are associated with differential clinical responses to methotrexate treatment in rheumatoid arthritis., PMID:38840915
Virus-like structures for combination antigen protein mRNA vaccination., PMID:38802667
Thermodynamics-Guided Design Reveals a Cooperative Hydrogen Bond in DC-SIGN-targeted Glycomimetics., PMID:38771131
Dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) is a cellular receptor for delta inulin adjuvant., PMID:38757764
For research use only. Not for human or drug use.
