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Anti-NRGN Polyclonal Antibody

Catalog #:   PHJ32301 Specific References (24) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q92686
Overview

Catalog No.

PHJ32301

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human NRGN (Met1-Ala67).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

RC3,Neurogranin,Ng,NRGN

Purification

Purified by antigen affinity column.

Accession

Q92686

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with NRGN antibody (PHJ32301) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 9 kDa
    Observed MW: 9 kDa
References

Neurogranin facilitates maintaining the immunosuppressive state of hepatocellular carcinoma by promoting TGF-β1 secretion., PMID:40316076

Transcriptomic profiling of severe and critical COVID-19 patients reveals alterations in expression, splicing and polyadenylation., PMID:40251257

CSF levels of brain-derived proteins correlate with brain ventricular volume in cognitively healthy 70-year-olds., PMID:39668376

Benchmarking of a multi-biomarker low-volume panel for Alzheimer's Disease and related dementia research., PMID:38947090

CSF protein ratios with enhanced potential to reflect Alzheimer's disease pathology and neurodegeneration., PMID:38350954

Synaptic proteins in neuron-derived extracellular vesicles as biomarkers for Alzheimer's disease: novel methodology and clinical proof of concept., PMID:37842184

Growth Hormone-Releasing Hormone Modulation of Neuronal Exosome Biomarkers in Mild Cognitive Impairment., PMID:30372675

CSF profiling of the human brain enriched proteome reveals associations of neuromodulin and neurogranin to Alzheimer's disease., PMID:27604409

Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile., PMID:27408937

Serum neurogranin measurement as a biomarker of acute traumatic brain injury., PMID:26025774

Transitory and activity-dependent expression of neurogranin in olfactory bulb tufted cells during mouse postnatal development., PMID:22592880

Neurogranin is expressed by principal cells but not interneurons in the rodent and monkey neocortex and hippocampus., PMID:15389613

Regulation of vascular L-type Ca2+ channels by phosphatidylinositol 3,4,5-trisphosphate., PMID:15242973

The human RC3 gene homolog, NRGN contains a thyroid hormone-responsive element located in the first intron., PMID:9886843

Nitric oxide modification of rat brain neurogranin affects its phosphorylation by protein kinase C and affinity for calmodulin., PMID:8798403

Neurogranin is locally concentrated in rat cortical and hippocampal neurons., PMID:8891262

Neurogranin in the development of the rat telencephalon., PMID:8783271

Sleep deprivation differentially alters the mRNA and protein levels of neurogranin in rat brain., PMID:7583240

Antibodies to postsynaptic PKC substrate neurogranin prevent long-term potentiation in hippocampal CA1 neurons., PMID:7620629

Regulation of p68 RNA helicase by calmodulin and protein kinase C., PMID:7525583

Monoclonal antibody NM2 recognizes the protein kinase C phosphorylation site in B-50 (GAP-43) and in neurogranin (BICKS)., PMID:8113810

Rapid purification, site-directed mutagenesis, and initial characterization of recombinant RC3/neurogranin., PMID:7654517

Thyroid hormone regulation of RC3, a brain-specific gene encoding a protein kinase-C substrate., PMID:8344193

Neurogranin: immunocytochemical localization of a brain-specific protein kinase C substrate., PMID:2269883

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Anti-NRGN Polyclonal Antibody [PHJ32301]
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